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Telmisartan+Metoprolol Tartarate

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Molecule Summary

Uses
High blood pressure
Therapy
Anti-Hypertensive
Side Effects
Dizziness, headache, nausea, vomiting, stomach pain, tiredness, slow heart rate, low blood pressure
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Molecule Description

Telmisartan+Metoprolol Tartarate is an antihypertensive medication used to treat high blood pressure when it cannot be controlled with a single medication. It is a combination medicine containing metoprolol and telmisartan. This medication works by relaxing the blood vessels and reducing elevated blood pressure. Do not stop taking this medicine suddenly, as it may cause sudden hypertensive crises and further deteriorate your health. Always take it as prescribed and advised by your doctor. Visit a nearby clinic or hospital if you experience any side effects that worsen or persist. Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding, and disclose all medications and supplements you are taking, along with any conditions or diseases you have before starting Telmisartan+Metoprolol Tartarate.

Uses

Telmisartan+Metoprolol Tartarate is used for the treatment of high blood pressure.

Contraindications

When should one not use Telmisartan+Metoprolol Tartarate

  • If you have any allergic reaction to Metoprolol, Telmisartan or any of the ingredient of Telmisartan+Metoprolol Tartarate
  • If you are suffering from heart problems like heart block, heart failure or sick sinus syndrome (abnormal heart rhythms)
  • If you have a specific type of angina called Prinzmetal's angina
  • If you have reduced blood supply to your limbs (peripheral arterial disease)
  • If you have asthma or chronic obstructive pulmonary disease (COPD)
  • If you are suffering from an adrenal gland tumour (phaeochromocytoma)
  • If you have a condition called metabolic acidosis (increased acidity in your body or are on medicines to treat irregular heart rhythm like disopyramide)
  • If you have diabetes associated with frequent low blood sugar levels
  • If you are suffering from low blood pressure (hypotension)
  • If you are pregnant
  • If you have blockage of any duct that carries bile from the liver to gallbladder (obstructive biliary disorders) or severe liver disease
  • If you have diabetes and you are taking Aliskiren

Side effects

Common side effects of this drug are:

  • Dizziness
  • Headache
  • Nausea
  • Vomiting
  • Stomach pain
  • Tiredness
  • Slow heart rate
  • Low blood pressure

Precautions and Warnings

Pregnancy

Pregnancy

Pregnant women should not take Telmisartan+Metoprolol Tartarate as it may be unsafe during pregnancy and cause serious harm to the baby. If you are on this medication and are pregnant, think you may be or are planning pregnancy, inform the same to your doctor, so that your prescription can be changed.

Breast Feeding

Breast Feeding

Telmisartan+Metoprolol Tartarate passes into the mother's milk. Thus, you should not take this medicine if you are breastfeeding. In the case of breastfeeding, the infant needs close monitoring for side effects like slowing heart rate.

Driving

Driving

Telmisartan+Metoprolol Tartarate may affect your ability to drive or operate machines. Do not drive or operate machines if you experience dizziness, tiredness and drowsiness.

Alcohol

Alcohol

Alcohol consumption, along with Telmisartan+Metoprolol Tartarate can lower your blood pressure and can increase side effects like sleepiness, dizziness or drowsiness. It is advised not to consume alcohol during the treatment.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have asthma
  • You have diabetes, caution is required. Metoprolol may cause low blood sugar levels and also change the body's response to low blood sugar. You may experience warning signs of low blood sugar such as an increase in heart rate, sweating, hunger pangs, headache, etc.
  • You have a tumour of adrenal gland tissue (Pheochromocytoma)
  • You have an overactive thyroid (a condition when the thyroid gland produces too much of the thyroxine hormone)
  • You are suffering from psoriasis
  • You have a circulation related problem in the toes, arm, legs or fingers
  • You are suffering from a type of chest pain (Prinzmetal's angina)
  • You recently had any heart attack, chest pain or heart surgery
  • You have kidney disease or have had a kidney transplant or liver disease
  • You are known to have narrowed or blockage of the blood vessels of one or both kidneys
  • You develop diarrhoea or vomiting, this dehydration can result in low blood pressure, have an adequate amount of water and fluids
  • You are suffering from low blood pressure (hypotension)
  • You have a high level of potassium in your blood
  • You are taking medicines like Ramipril and Lisinopril

Mode of Action

How Does It Work?

  • Metoprolol works by slowing the heart rate and relaxing blood vessels and reduces high blood pressure.
  • Angiotensin II is a substance produced in the body which causes the narrowing of blood vessels. It leads to an increase in blood pressure.
  • Telmisartan prevents the binding of Angiotensin II to its receptors and causes the blood vessels to relax and lowers the blood pressure.

Interactions

Interactions with other medicines

  • Avoid heart rhythm medications like Amiodarone, Disopyramide, and Digoxin.
  • Use caution with blood pressure medications such as Prazosin, Tamsulosin, Terazosin, Doxazosin, Clonidine, Guanfacine, Moxonidine, Methyldopa, Rilmenidine, and Nitroglycerine.
  • Be careful with Lidocaine and general anesthetics.
  • Interacts with diabetes medications, including Aliskiren.
  • Do not combine with potassium supplements or potassium-sparing diuretics.
  • Use caution with blood thinners like Warfarin, Heparin, and NSAIDs.
  • Be cautious with psychiatric medications like Fluoxetine, Lithium, Paroxetine, Bupropion, Thioridazine, Diphenhydramine, Hydroxychloroquine, and Mefloquine.
  • Avoid with MAOIs.
  • May reduce the effectiveness of Ergotamine.
  • Cimetidine can increase Metoprolol levels.
  • Trimethoprim, Rifampicin, and Terbinafine can affect how Metoprolol works.
  • Telmisartan can increase the levels of Cyclosporin and Tacrolimus.
  • Diuretics can increase the risk of low blood pressure.

Interactions with food items

It is advised to avoid high potassium-containing foods like spinach, broccoli and potatoes as Telmisartan is known to increase blood potassium levels.

Dosage

Overdose

Symptoms of overdose may include low blood pressure, irregular heartbeat, heart failure, shock, loss of consciousness, coma, nausea, vomiting, bluish colour of the lips, tongue and skin, low levels of potassium or calcium in blood, dizziness and kidney failure. In case of an overdose with Telmisartan+Metoprolol Tartarate, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed a dose of Telmisartan+Metoprolol Tartarate, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of this medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

If you experience any symptoms such as dizziness, syncope, vision problems, sexual dysfunction, slowing of heart rate, etc., immediately report to your doctor. The doctor can adjust your dose depending on your blood pressure, heart rate, level of this medicine in your serum and other such important factors.

Limit intake of salt in diet especially pickles and packaged foods like chips contain excess salt and should be avoided Have less amount of potassium-containing foods like spinach, broccoli or banana Limit meat intake in your diet Instead of having packaged snacks, prefer fresh cut fruits as they are rich in vitamins and fibre

If you stop Telmisartan+Metoprolol Tartarate suddenly, you can suffer from chest pain, irregular heartbeat or heart attack. Your doctor might tell you to decrease the dose gradually. Don't suddenly stop taking this medicine without talking to your doctor.

Telmisartan+Metoprolol Tartarate is an antihypertensive medicine that is used for the treatment of high blood pressure.

No, Telmisartan+Metoprolol Tartarate is not a blood thinner. It relaxes the blood vessels and increases the supply of blood and oxygen to the heart, thus lowering blood pressure.

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