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Telmisartan+Atorvastatin

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Molecule Summary

Uses
High blood pressure with raised cholesterol
Therapy
Anti-Hypertensive And Hypolipidemic Drugs
Side Effects
Headache, nausea, diarrhoea, dizziness, body pain
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Molecule Description

Telmisartan+Atorvastatin is used to treat high blood pressure when it exists with increased or deranged cholesterol. It contains atorvastatin and telmisartan as active ingredients. It must be taken as directed by the doctor and in doses and duration as prescribed. Before using Telmisartan+Atorvastatin, inform the doctor if you are pregnant, planning a pregnancy or are breastfeeding and regarding the medical history.

Uses

Telmisartan+Atorvastatin is used to treat hypertension (high blood pressure) when it exists with increased/deranged cholesterol.

Contraindications

When should one not use Telmisartan+Atorvastatin

  • If you are allergic to atorvastatin, telmisartan or other ingredients of Telmisartan+Atorvastatin.
  • If you have or had any liver disease or abnormality in liver function test.
  • If you are being treated with medicines for hepatitis C like Glecaprevir/Pibrentasvir.
  • If you are pregnant, may be pregnant, are planning a pregnancy or are breastfeeding.
  • If you have blockage of the duct that takes bile from the liver to the gallbladder (obstructive biliary disorders).
  • If you have diabetes or kidney disorder and you have been treated with aliskiren (a medicine used to treat high blood pressure).

Side effects

Common side effects of this drug are:

  • Headache
  • Nausea
  • Diarrhoea
  • Dizziness
  • Body pain

Precautions and Warnings

Pregnancy

Pregnancy

Avoid during pregnancy as it can be unsafe during pregnancy. If you are pregnant or become pregnant, discontinue the treatment with this medicine and contact the doctor. If you are a woman of childbearing age, discuss with the physician the importance of birth control methods and potential hazards to the unborn baby.

Breast Feeding

Breast Feeding

Avoid while breastfeeding as it is unknown if its components pass into breast milk.

Driving

Driving

Telmisartan+Atorvastatin may make you feel dizzy, avoid driving if you do not feel well or are unable to be alert.

Alcohol

Alcohol

Avoid consuming alcohol while on treatment with Telmisartan+Atorvastatin. Alcohol may raise your blood pressure. Consult the doctor about your drinking habits and they may suggest what will work for you.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have liver or kidney disease or have a kidney transplant.
  • You develop muscle problems after using other lipid-lowering medicine.
  • You are taking medicines for bacterial infection like fusidic acid.
  • You have difficulty in breathing, thyroid problem, diabetes or other heart-related condition.
  • You suffer from narrowing or blockage of the blood vessels of one or both kidneys.
  • You develop diarrhoea, vomiting, dehydration, which results in low blood pressure. Increase intake of water and fluids.
  • You suffer from water and salt retention in the body along with an imbalance of blood minerals (raised aldosterone levels).

Mode of Action

How Does It Work?

  • Cholesterol is made by an enzyme HMG-CoA reductase. Atorvastatin inhibits this enzyme and lowers bad cholesterol levels (LDL levels), triglyceride levels and other lipids or fats in the blood. It increases the good cholesterol known as high-density lipoprotein (HDL) levels.
  • Angiotensin II is a substance produced in the body that causes the narrowing of blood vessels. It leads to an increase in blood pressure. Telmisartan prevents the binding of Angiotensin II to its receptors and causes the blood vessels to relax and lowers the blood pressure.

Interactions

Interactions with other medicines

  • Some medicines affect the way Telmisartan+Atorvastatin works or this medicine itself reduces the effectiveness of other medicines taken at the same time.
  • Inform the doctor regarding the medicines, supplements or herbals you take or might take to avoid possible interaction. Inform the doctor regarding planned surgery or vaccination schedule.
  • If you are using blood thinners, antibiotics, steroids, pain killers, diuretics (water pills), antacids, medicines that may increase blood potassium levels like salt containing potassium and potassium-sparing diuretics, medicines to treat your heart problems, mental health problems, fits, diabetes, HIV infection.

Interactions with food items

  • Intake of grapefruit juice must be limited in quantity as grapefruit may alter the effect of Telmisartan+Atorvastatin.
  • Avoid high potassium-containing foods like spinach, broccoli and potatoes.

Dosage

Overdose

Symptoms of an overdose are irregular heartbeat, dizziness, low blood pressure, loss of consciousness. If you have taken too much of Telmisartan+Atorvastatin, contact the doctor or visit the nearest hospital.

Missed a Dose

If you have missed taking a dose of Telmisartan+Atorvastatin, take it as soon as you remember. If it's time for the next dose, skip the missed dose and continue with the regular dosing schedule. Avoid taking a double dose to compensate for the missed one.

Frequently Asked Questions (FAQs)

You may experience side effects like headache, dizziness, nausea, diarrhoea while on treatment with Telmisartan+Atorvastatin.

Limit intake of salt in the diet, pickles and packaged foods like chips as they contain excess salt and must be avoided. Avoid food rich in potassium like spinach, broccoli or banana, fruits and potassium-containing supplements. Instead of having packaged snacks, have fresh-cut fruits as they are rich in vitamins and fibre. Limit alcohol consumption and avoid smoking.

Take Telmisartan+Atorvastatin as directed by the doctor. Swallow it as a whole with a glass of water. Do not cut, break or chew the medicine.

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