Rosuvastatin+Aspirin / Acetyl Salicylic Acid
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Molecule Summary
| Uses | Prevent the risk of having a heart attack or stroke, lowers blood cholesterol levels |
| Therapy | Anti-Platelet And Hypolipidemic Drugs |
| Side Effects | Headache, dizziness, sleepiness, nausea |
Medicines
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19k pincodes
Molecule Description
Rosuvastatin+Aspirin / Acetyl Salicylic Acid is a combination medication used to prevent or reduce the risk of heart attacks or strokes, and it also helps to lower blood cholesterol levels. Its main components are acetylsalicylic acid and rosuvastatin. Rosuvastatin+Aspirin / Acetyl Salicylic Acid should be taken as directed by your doctor. Do not miss any doses or discontinue this medicine without consulting your doctor. Avoid smoking and consuming alcohol while undergoing treatment with this medication. You should exercise regularly and be mindful of your diet. Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding and about all the medicines and supplements you take, along with any conditions or diseases you have, before starting Rosuvastatin+Aspirin / Acetyl Salicylic Acid.
Uses
Rosuvastatin+Aspirin / Acetyl Salicylic Acid is used in reducing the risk of having a heart attack or stroke. It also helps in lowering blood cholesterol and fat levels.
Contraindications
When should one not use Rosuvastatin+Aspirin / Acetyl Salicylic Acid
- If you have any allergic reactions to Acetylsalicylic Acid, Rosuvastatin, or any of the components of Rosuvastatin+Aspirin / Acetyl Salicylic Acid.
- If you have active liver disease or severe kidney problems.
- If you are pregnant or breastfeeding.
- If you are suffering from any bleeding disorders or blood clotting issues.
- If you have a history of ulcers in the stomach or small intestine.
- If you are taking cyclosporine (used in rheumatoid arthritis or after organ transplants) or methotrexate (used in cancer treatment).
- If you've had an asthmatic attack or any severe allergic reactions like itching, swelling, or difficulty breathing or swallowing, etc.
- Rosuvastatin+Aspirin / Acetyl Salicylic Acid is not recommended for use in children with viral infections due to the risk of Reye's syndrome.
Side effects
Common side effects of this drug are:
- Headache
- Dizziness
- Sleepiness
- Nausea
- Stomach pain
- Body or muscle pain
- Tiredness
- Weakness
- Increased risk of bleeding
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have any unusual bleeding.
- You are above the age of 70 years.
- You regularly consume too much alcohol.
- You have stomach or small intestine problems.
- You are suffering from gout or any thyroid problems.
- You have diabetes or are at risk of developing diabetes.
- You are undergoing surgery or had a surgery recently.
- You have problems with your heart, kidney or liver problems.
- You have glucose 6-phosphate dehydrogenase (G6PD) deficiency.
- You have muscle aches or pains or family history of muscle problems.
- You are taking medicines to lower cholesterol like gemfibrozil, fenofibrate.
- You are suffering from asthma or any lung disease, then this medicine can worsen your asthma.
- You experience heavy menstrual bleeding, do not take this medicine as it can increase the bleeding.
- You are on or have taken a medicine- fusidic acid to treat your bacterial infections in the last 7 days.
- Rosuvastatin+Aspirin / Acetyl Salicylic Acid should not be used in children below the age of 16 years unless there are more benefits than risk.
Mode of Action
How Does It Work?
- Rosuvastatin+Aspirin / Acetyl Salicylic Acid works by the combined action of Acetylsalicylic Acid and Rosuvastatin.
- Acetylsalicylic Acid works by stopping the platelets from forming a clot so that the blood can flow easily and without any obstruction.
- Rosuvastatin works by inhibiting or blocking an enzyme which is needed in the body to make cholesterol, reducing the bad cholesterol and increasing the good cholesterol in the blood.
Interactions
Interactions with other medicines
- Some medicines can affect how Rosuvastatin+Aspirin / Acetyl Salicylic Acid functions, or this medicine itself can diminish the effectiveness of other medicines when taken concurrently. Inform your doctor about all the medicines, supplements, or herbal products you are currently taking or may consider taking to prevent any possible interactions.
- Rosuvastatin+Aspirin / Acetyl Salicylic Acid must not be used alongside methotrexate (used in cancer treatment) as it could be harmful when used together. Avoid taking this medicine with fusidic acid (a medication for bacterial infections), as simultaneous treatment can lead to serious muscle problems.
- You may be at an increased risk of muscle damage or severe side effects if taken with cyclosporine, gemfibrozil, fenofibrate, tacrolimus, or ezetimibe. Therefore, caution is advised. The concurrent use of this medicine with medications like probenecid (used to treat gout) is not recommended, as it may alter the effects of probenecid.
- Blood thinners such as warfarin and heparin, as well as medications used to treat pain and inflammation like aspirin, ibuprofen, and naproxen, can increase the risk of bleeding.
- Medications used to treat stomach acidity, such as antacids, should not be taken within at least two hours of this medicine.
- Metamizole (a painkiller) interferes with how this medicine works; thus, concurrent use should be avoided. Exercise caution when using this medicine alongside oral contraceptives or during hormone replacement therapy.
- Other medicines such as lithium, digoxin, ritonavir, erythromycin, and potassium supplements (amiloride, spironolactone) should be used with care in conjunction with Rosuvastatin+Aspirin / Acetyl Salicylic Acid.
Interactions with food items
You should avoid grapefruit juice while on treatment with Rosuvastatin+Aspirin / Acetyl Salicylic Acid.
Dosage
Overdose
- Overdose of Rosuvastatin+Aspirin / Acetyl Salicylic Acid may cause symptoms like ringing in the ears, dizziness, headache, nausea, vomiting, stomach pain, sweating, fever.
- Seek urgent medical help if you experience any such symptoms or feel you have taken too much of Rosuvastatin+Aspirin / Acetyl Salicylic Acid.
Missed a Dose
In case you've missed any dose of Rosuvastatin+Aspirin / Acetyl Salicylic Acid, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Avoid taking a double dose to compensate for the missed dose.
Frequently Asked Questions (FAQs)
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References:
- Aspirin 75mg Gastro-Resistant Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 2 June 2026]
- Aspirin 75mg Gastro-Resistant Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 2 June 2026]
- Barrett CD, Moore HB, Moore EE, Chandler J, Sauaia A. Combination of aspirin and rosuvastatin for reduction of venous thromboembolism in severely injured patients: a double-blind, placebo-controlled, pragmatic randomized phase II clinical trial (The STAT Trial). Blood Coagul Fibrinolysis. 2023 Dec 1;34(8):499-507. [cited 2 Jun 2026]
- Fu J, Wang T, Li B, Zhao N. The Efficacy of Rosuvastatin, Amlodipine, and Aspirin in the Treatment of Hypertension with Coronary Heart Disease and Its Effect on Platelet Aggregation. Dis Markers. 2022 Oct 15;2022:1111438. [cited 2 Jun 2026]
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