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Rosuvastatin+Aspirin / Acetyl Salicylic Acid

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Molecule Summary

Uses
Prevent the risk of having a heart attack or stroke, lowers blood cholesterol levels
Therapy
Anti-Platelet And Hypolipidemic Drugs
Side Effects
Headache, dizziness, sleepiness, nausea
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Molecule Description

Rosuvastatin+Aspirin / Acetyl Salicylic Acid is a combination medication used to prevent or reduce the risk of heart attacks or strokes, and it also helps to lower blood cholesterol levels. Its main components are acetylsalicylic acid and rosuvastatin. Rosuvastatin+Aspirin / Acetyl Salicylic Acid should be taken as directed by your doctor. Do not miss any doses or discontinue this medicine without consulting your doctor. Avoid smoking and consuming alcohol while undergoing treatment with this medication. You should exercise regularly and be mindful of your diet. Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding and about all the medicines and supplements you take, along with any conditions or diseases you have, before starting Rosuvastatin+Aspirin / Acetyl Salicylic Acid.

Uses

Rosuvastatin+Aspirin / Acetyl Salicylic Acid is used in reducing the risk of having a heart attack or stroke. It also helps in lowering blood cholesterol and fat levels.

Contraindications

When should one not use Rosuvastatin+Aspirin / Acetyl Salicylic Acid

  • If you have any allergic reactions to Acetylsalicylic Acid, Rosuvastatin, or any of the components of Rosuvastatin+Aspirin / Acetyl Salicylic Acid.
  • If you have active liver disease or severe kidney problems.
  • If you are pregnant or breastfeeding.
  • If you are suffering from any bleeding disorders or blood clotting issues.
  • If you have a history of ulcers in the stomach or small intestine.
  • If you are taking cyclosporine (used in rheumatoid arthritis or after organ transplants) or methotrexate (used in cancer treatment).
  • If you've had an asthmatic attack or any severe allergic reactions like itching, swelling, or difficulty breathing or swallowing, etc.
  • Rosuvastatin+Aspirin / Acetyl Salicylic Acid is not recommended for use in children with viral infections due to the risk of Reye's syndrome.

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Sleepiness
  • Nausea
  • Stomach pain
  • Body or muscle pain
  • Tiredness
  • Weakness
  • Increased risk of bleeding

Precautions and Warnings

Pregnancy

Pregnancy

Rosuvastatin+Aspirin / Acetyl Salicylic Acid must not be taken during pregnancy as it may cause harm to the unborn baby. When pregnancy is detected, this medicine should be discontinued immediately. Proper birth control measures should be taken while on treatment. It is essential to consult a doctor before starting any medicine during pregnancy.

Breast Feeding

Breast Feeding

Components of Rosuvastatin+Aspirin / Acetyl Salicylic Acid pass into breastmilk. Hence, avoid using this medicine while breastfeeding. It is essential to consult a doctor before starting any medicine during breastfeeding.

Driving

Driving

Rosuvastatin+Aspirin / Acetyl Salicylic Acid may make you feel dizzy and sleepy. Hence, either be cautious or avoid driving while on treatment with this medicine.

Alcohol

Alcohol

Consuming alcohol along with Rosuvastatin+Aspirin / Acetyl Salicylic Acid may increase the risk of liver problems. It is advised to avoid alcohol during the treatment.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have any unusual bleeding.
  • You are above the age of 70 years.
  • You regularly consume too much alcohol.
  • You have stomach or small intestine problems.
  • You are suffering from gout or any thyroid problems.
  • You have diabetes or are at risk of developing diabetes.
  • You are undergoing surgery or had a surgery recently.
  • You have problems with your heart, kidney or liver problems.
  • You have glucose 6-phosphate dehydrogenase (G6PD) deficiency.
  • You have muscle aches or pains or family history of muscle problems.
  • You are taking medicines to lower cholesterol like gemfibrozil, fenofibrate.
  • You are suffering from asthma or any lung disease, then this medicine can worsen your asthma.
  • You experience heavy menstrual bleeding, do not take this medicine as it can increase the bleeding.
  • You are on or have taken a medicine- fusidic acid to treat your bacterial infections in the last 7 days.
  • Rosuvastatin+Aspirin / Acetyl Salicylic Acid should not be used in children below the age of 16 years unless there are more benefits than risk.

Mode of Action

How Does It Work?

  • Rosuvastatin+Aspirin / Acetyl Salicylic Acid works by the combined action of Acetylsalicylic Acid and Rosuvastatin.
  • Acetylsalicylic Acid works by stopping the platelets from forming a clot so that the blood can flow easily and without any obstruction.
  • Rosuvastatin works by inhibiting or blocking an enzyme which is needed in the body to make cholesterol, reducing the bad cholesterol and increasing the good cholesterol in the blood.

Interactions

Interactions with other medicines

  • Some medicines can affect how Rosuvastatin+Aspirin / Acetyl Salicylic Acid functions, or this medicine itself can diminish the effectiveness of other medicines when taken concurrently. Inform your doctor about all the medicines, supplements, or herbal products you are currently taking or may consider taking to prevent any possible interactions.
  • Rosuvastatin+Aspirin / Acetyl Salicylic Acid must not be used alongside methotrexate (used in cancer treatment) as it could be harmful when used together. Avoid taking this medicine with fusidic acid (a medication for bacterial infections), as simultaneous treatment can lead to serious muscle problems.
  • You may be at an increased risk of muscle damage or severe side effects if taken with cyclosporine, gemfibrozil, fenofibrate, tacrolimus, or ezetimibe. Therefore, caution is advised. The concurrent use of this medicine with medications like probenecid (used to treat gout) is not recommended, as it may alter the effects of probenecid.
  • Blood thinners such as warfarin and heparin, as well as medications used to treat pain and inflammation like aspirin, ibuprofen, and naproxen, can increase the risk of bleeding.
  • Medications used to treat stomach acidity, such as antacids, should not be taken within at least two hours of this medicine.
  • Metamizole (a painkiller) interferes with how this medicine works; thus, concurrent use should be avoided. Exercise caution when using this medicine alongside oral contraceptives or during hormone replacement therapy.
  • Other medicines such as lithium, digoxin, ritonavir, erythromycin, and potassium supplements (amiloride, spironolactone) should be used with care in conjunction with Rosuvastatin+Aspirin / Acetyl Salicylic Acid.

Interactions with food items

You should avoid grapefruit juice while on treatment with Rosuvastatin+Aspirin / Acetyl Salicylic Acid.

Dosage

Overdose

  • Overdose of Rosuvastatin+Aspirin / Acetyl Salicylic Acid may cause symptoms like ringing in the ears, dizziness, headache, nausea, vomiting, stomach pain, sweating, fever.
  • Seek urgent medical help if you experience any such symptoms or feel you have taken too much of Rosuvastatin+Aspirin / Acetyl Salicylic Acid.

Missed a Dose

In case you've missed any dose of Rosuvastatin+Aspirin / Acetyl Salicylic Acid, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Avoid taking a double dose to compensate for the missed dose.

Frequently Asked Questions (FAQs)

You need to take Rosuvastatin+Aspirin / Acetyl Salicylic Acid as directed by your doctor.

Inform the doctor about your detailed medical & surgical history.

Inform your doctor if you have heart, liver or kidney disease.

Inform your doctor if you are pregnant, breastfeeding or planning to have a baby.

Rosuvastatin+Aspirin / Acetyl Salicylic Acid may interact with other medicines. Hence, inform your doctor if you are taking any other medicines, including supplements or herbal products. Also, inform your doctor if you are stopping any medicine.

You need to be on a diet that reduces your cholesterol levels before starting this medicine. Avoid drinking grapefruit juice while taking this medicine and avoid alcohol. Consult your doctor for more details.

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