Recombinant Human Erythropoietin Alfa

Uses	Anaemia
Therapy	Haematinics
Side Effects	Nausea, vomiting, diarrhoea, indigestion, fever

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Molecule Description

Recombinant Human Erythropoietin Alfa is used to treat low red blood cell count (anaemia) that occurs due to kidney disease, cancer chemotherapy, or HIV infection treatment. Anaemia is a condition where there is a shortage of enough healthy red blood cells to carry oxygen to your body's tissues. Recombinant Human Erythropoietin Alfa contains erythropoietin as the active substance that works by increasing the red blood cell count in the body. It can be used in both adults and children. It will be given to you by your doctor or nurse. Do not self-inject this medicine.

Uses

Recombinant Human Erythropoietin Alfa is used for the treatment of anaemia that occurs because of cancer chemotherapy, HIV infection treatment with zidovudine, or kidney disease.
Recombinant Human Erythropoietin Alfa is also used to reduce the need for red blood cell transfusions in patients who are at high risk for blood loss due to planned, noncardiac, nonvascular surgery.

Contraindications

When should one not use Recombinant Human Erythropoietin Alfa

If you are allergic to erythropoietin or any other ingredient of Recombinant Human Erythropoietin Alfa.
If you are allergic to mammalian cell-derived products or albumin.
If you have high blood pressure that is not properly controlled.
If you have a condition called pure red cell aplasia where there is reduced or stopped red blood cell production.

Side effects

Common side effects of this drug are:

Nausea
Vomiting
Diarrhoea
Indigestion
Fever

Precautions and Warnings

Pregnancy

There is limited information on the effect of Recombinant Human Erythropoietin Alfa in pregnancy. This medicine should be used in pregnancy only if your doctor recommends it after assessing the need and the risk.

Breast Feeding

No information is available if Recombinant Human Erythropoietin Alfa passes into human breast milk. This medicine may be used in breastfeeding women if recommended by the doctor.

Driving

Recombinant Human Erythropoietin Alfa may cause fits/seizures. If you experience any such symptoms which may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

There is limited information available regarding the interaction of alcohol with Recombinant Human Erythropoietin Alfa. Ask your doctor for advice on alcohol intake along with Recombinant Human Erythropoietin Alfa.

Other General Warnings

Talk to your doctor if

You have kidney or heart disease.
You have cancer.
You are undergoing dialysis.
You have a haemoglobin level greater than 11g/dL with heart or blood vessel disorder.
You are scheduled for surgery like coronary artery bypass graft surgery (CABG) or orthopaedic surgery.
You are undergoing treatment for hepatitis C with medicines like interferon and ribavirin.
You have high blood pressure that is not properly controlled.
You have iron deficiency, infection, inflammation, or bleeding.
You experience seizures/fits after taking Recombinant Human Erythropoietin Alfa.
You develop symptoms like skin rashes, swelling of the face and lips, red spots after taking this medicine.

Mode of Action

How Does It Work?

Recombinant Human Erythropoietin Alfa promotes the formation of red blood cells in the bone marrow which increases the red blood cell count in the body.

Interactions

Interactions with other medicines

Some medicines can affect the way Recombinant Human Erythropoietin Alfa works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.

Dosage

Overdose

Recombinant Human Erythropoietin Alfa will be given to you by a doctor or nurse, and hence, the chances of an overdose are unlikely.

Missed a Dose

If you have missed a dose of Recombinant Human Erythropoietin Alfa, please consult your doctor. Your doctor will recommend the best time for you or your child to receive the next dose.

Frequently Asked Questions (FAQs)

Recombinant Human Erythropoietin Alfa is used for the treatment of anaemia that occurs because of cancer chemotherapy, HIV infection treatment with zidovudine, or kidney disease. It is also used to reduce the need for red blood cell transfusions in patients who are at high risk for blood loss due to planned, noncardiac, nonvascular surgery.

Recombinant Human Erythropoietin Alfa will be given to you either through the veins (intravenous) or under the skin (subcutaneous).

You have to store this medicine in the refrigerator. Do not freeze this medicine.