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Prasugrel

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Molecule Description

Prasugrel is used to prevent the formation of blood clots.

Uses

Prasugrel is used in combination with low dose Aspirin in patients with chest pain, stroke, and heart attacks that have undergone angioplasty procedures (a procedure to open blocked blood vessels that supply blood to the heart). In some processes, a tube (stent) is placed in one or more coronary arteries. Prasugrel is used to prevent thrombosis.

Contraindications

When should one not use Prasugrel

  • Allergic to the medicine
  • Stomach ulcers
  • Severe liver diseases
  • Any conditions that cause bleeding in the intestines
  • Hemophilia and other diseases that show bleeding tendencies

Side effects

Common side effects of this drug are:

  • Dizziness
  • Excessive fatigue
  • Cough
  • Decreased urination
  • Headache, confusion
  • Nausea, stomach pain
  • Itching rashes
  • Numbness or weakness
  • Fever
  • Yellowish discoloration of skin

Precautions and Warnings

Pregnancy

Pregnancy

This medicine is probably unsafe to use in pregnant women. Discuss with your doctor before consuming this medicine.

Breast Feeding

Breast Feeding

No specific information is available on the use of Prasugrel during breastfeeding. Hence it is better not to use unless prescribed by a physician.

Driving

Driving

This medicine probably does not affect your ability to drive.

Alcohol

Alcohol

Use of alcohol while using this medicine may increase your risk of stomach bleeding.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • This medicine is not for use in children and adolescents who are below 18 years of age
  • Elderly above 75 years of age
  • Any recent surgery
  • Any history of bleeding disorders
  • Bodyweight less than 60 kg
  • Any history of kidney disease

Mode of Action

How Does It Work?

Prasugrel is an inhibitor of platelet (type of blood cells) activation and aggregation. This prevents platelets from forming a clot, and the blood can flow easily.

Interactions

Interactions with other medicines

  • Blood thinners such as Warfarin, Heparin
  • Non-Steroidal Anti-Inflammatory Drugs (pain killers) such as Ibuprofen and Naproxen

Interactions with food items

Avoid alcohol while on treatment with Prasugrel as it increases the side effects.

Dietary Restrictions

No information is available on dietary restrictions while you are taking Prasugrel, consult your doctor or pharmacist for further details.

Dosage

Overdose

If you take an overdose of Prasugrel, the complications may be fatal. Any of the known side effects of Prasugrel, especially bleeding symptoms, can be seen in an overdose. You must seek emergency medical attention immediately.

Missed a Dose

Take the missed dose as soon as you remember. If you have missed a dose then do not take extra medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

Inform your doctor if you are due to undergo any surgeries, including dental procedures or heart bypass surgeryMonitor bleeding and clotting investigation profile while on treatment with PrasugrelIf you notice the following symptoms while on therapy with Prasugrel, inform your doctor immediatelyUnexplained or severe bleedingBlood in urine or motionVomiting out bloodCoughing out blood

Store this medicine at room temperature should be away from excess heat and moistureKeep out of the reach of children

Prasugrel comes in the tablet or capsule form taken orally after a meal.

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