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Paroxetine

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Molecule Summary

Uses
Depression, Anxiety-related disorders such as OCD/ Obsessive Compulsive Disorder and panic disorder
Therapy
Anti-Depressant
Side Effects
Dry mouth, Nausea, Loss of appetite, Fatigue, Dizziness, Constipation
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Molecule Description

Paroxetine is an antidepressant (medicines that fight depression). It helps manage the symptoms of depression and anxiety-related disorders such as OCD (Obsessive Compulsive Disorder) and panic disorder.

Uses

  • Paroxetine manages the symptoms of depression.
  • Paroxetine also manages anxiety-related disorders such as Obsessive Compulsive Disorder and panic disorder.

Contraindications

When should one not use Paroxetine

  • If you have an allergy to Paroxetine or any other ingredient of this medicine
  • If you are under 18 years of age

Side effects

Common side effects of this drug are:

  • Dry mouth
  • Nausea/ vomiting sensation
  • Loss of appetite
  • Fatigue/ extreme tiredness or body pain
  • Dizziness
  • Constipation/ difficulty in passing stools

Precautions and Warnings

Pregnancy

Pregnancy

Take Paroxetine during pregnancy only if your doctor advises. Paroxetine may be unsafe in pregnancy. It might harm your developing baby.

Breast Feeding

Breast Feeding

Take Paroxetine during breastfeeding only if your doctor advises.

Breast Feeding

Breast Feeding

Paroxetine may be unsafe during breastfeeding. Paroxetine may pass through the breastmilk and harm the baby.

Driving

Driving

Paroxetine can cause side effects such as drowsiness or dizziness. They can affect your ability to drive. It is also not safe to operate heavy machinery or do anything that requires clear focus. It is advisable to avoid these activities until you understand how your body responds to the medicine. Please discuss with your doctor for further details.

Alcohol

Alcohol

It is not safe to consume alcohol when you are on treatment with Paroxetine. Alcohol might increase the side effects of Paroxetine and cause adverse reactions.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • If you experience allergic reactions to Paroxetine such as difficulty breathing, rashes, itching, bluish skin colour, swelling of face, tongue, or throat. Contact your doctor or the emergency medical department immediately.
  • If you are experiencing sudden mood changes when you are on Paroxetine. Contact your doctor immediately.
  • If you are getting thoughts of harming yourself when you are on Paroxetine. Speak to your doctor immediately.
  • If you have kidney disease
  • If you have liver disease
  • If you have epilepsy (fits)
  • If you have diabetes (high blood sugar levels)
  • If you have heart disease
  • If you have glaucoma (increased pressure in the eyes)

Mode of Action

How Does It Work?

Paroxetine belongs to the class of medicines called antidepressants (medicines that fight depression.)

Interactions

Interactions with other medicines

  • Seek medical advice if you are on other antidepressant medicines like MAOI (Monoamine Oxidase inhibitors), for example, Rasagiline. Taking Paroxetine when you are on MAOI can cause severe life-threatening adverse reactions.
  • Seek medical advice if you are on medicines that fight infection, such as linezolid. Taking Paroxetine when you are on such medicines can cause life-threatening reactions.
  • Seek medical advice if you are on breast cancer medicines, such as Tamoxifen. Taking Paroxetine when you are on such medicines can reduce the efficacy of Tamoxifen and make breast cancer recur.
  • Inform your doctor if you are on any other medications before taking Paroxetine. Do not take any medication without informing your doctor.

Dosage

Overdose

If you suspect an overdose of Paroxetine, contact your doctor immediately or rush to the nearest emergency department.

Missed a Dose

If you missed taking your dosage of Paroxetine, take it as soon as you remember. If it is close to your next dose, skip the missed dose. Do not take two doses of Paroxetine simultaneously.

Frequently Asked Questions (FAQs)

Paroxetine decreases sex drive and can cause erectile dysfunction (failure to erect penis) or premature ejaculation (early release of semen). Usually, such side effects are temporary and disappear gradually as your body gets used to the medicine. However, if such symptoms are persistent, speak to your doctor.

Paroxetine takes around two to four weeks to show its effects. If you do not feel any better even after four weeks of treatment with Paroxetine, inform your doctor.

No. Paroxetine has minimal chances of addiction. However, be sure to follow your doctor's advice and dosage instructions.

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