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Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone

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Molecule Summary

Uses
High blood pressure
Therapy
Anti-Hypertensive
Side Effects
Electrolyte imbalance, headache, dizziness, loss of appetite, nausea, stomach pain, diarrhoea, indigestion, vomiting
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Molecule Description

Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone is an anti-hypertensive medicine used for the treatment of high blood pressure. It contains a combination of three active ingredients- olmesartan, cilnidipine and chlorthalidone. High blood pressure is a critical health condition that, if not treated, may affect organs like the brain, kidneys, etc. Taking this medicine regularly as prescribed by your doctor along with other lifestyle modifications can help you control your blood pressure. It is recommended to limit alcohol consumption and avoid smoking.

Uses

  • Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone is used for the treatment of high blood pressure.

Contraindications

When should one not use Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone

  • If you are allergic to any ingredients present in Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone.
  • If you are pregnant.
  • If you have diabetes or kidney-related disorders and taking aliskiren to treat high blood pressure.
  • If you suffer from severe low blood pressure or experienced shock recently.
  • As it is a combination of 3 different components, any condition which is contraindicated with any of these when taken alone should be considered contraindicated for this combination.

Side effects

Common side effects of this drug are:

  • Electrolyte imbalance
  • Headache
  • Dizziness
  • Loss of appetite
  • Nausea
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Vomiting

Precautions and Warnings

Pregnancy

Pregnancy

You should not take Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone during pregnancy or if you are planning to have a baby as it may cause harm to your unborn baby. If you become pregnant while taking this medicine, discontinue the treatment and immediately consult your doctor.

Breast Feeding

Breast Feeding

Components of this medicine pass into the breastmilk. However, the effect of this medicine on infants is not known. Tell your doctor if you are breastfeeding before initiating the treatment. Refrain from self-medication.

Driving

Driving

Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone may make you dizzy or tired, thus you need to be cautious while driving or operating machines.

Alcohol

Alcohol

You should avoid consuming alcohol while taking Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have an underlying medical condition such as very low blood pressure, heart disorder, liver or kidney problem, diabetes, problems with your adrenal glands etc.
  • You develop any allergic reaction after taking Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone.
  • You are on a low-salt diet.
  • You have gout.
  • You have severe diarrhoea or/and vomiting.
  • You are on treatment with high doses of water pills (furosemide, hydrochlorothiazide).
  • Your doctor has told you that you have high blood potassium levels.
  • This medicine is not recommended for use in children.
  • You are elderly (65 years or older).
  • You are pregnant, think you may be or are planning to have a baby.
  • You are taking other medicines to treat high blood pressure like ramipril, lisinopril, aliskiren etc.

Mode of Action

How Does It Work?

  • Olmesartan works by blocking the action of angiotensin II, a natural substance in the body that causes the blood vessels to tighten.
  • Cilnidipine is a calcium channel blocker that relaxes the blood vessels. Together they help relax blood vessels and allow the blood to flow easily.
  • Chlorthalidone works by controlling the blood pressure by removing the excess water from the body. Thereby, increase in the urine is the outcome.

Interactions

Interactions with other medicines

  • Certain medicines may affect the way Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone works or this medicine itself can affect the action of other medicines taken at the same time.
  • Inform your doctor about any other medicines, herbal preparations and supplements you are currently taking or might take to avoid any interaction with this combination of medicine.
  • Especially if you are taking potassium supplements, water pills, blood thinning medications like heparin, medicines used to relieve pain, swelling and inflammation like ibuprofen, aceclofenac, medicines for lowering the cholesterol, anti-epileptic medicines, other blood pressure medicines, certain antacids.
  • Concomitant use of Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone along with medicines for brain-related disorders like lithium is not recommended.

Interactions with food items

  • It is recommended to avoid foods rich in potassium like spinach, broccoli, banana, potatoes, etc.

Dosage

Overdose

Overdose of Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone may lead to low blood pressure (symptoms include dizziness, nausea, unconsciousness, blurred vision, etc.). Seek urgent medical help if you experience any such symptom or feel that you have taken too much of this medicine.

Missed a Dose

If you miss a dose of Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone, then take it as soon as you remember. If it is almost time for your next dose, then skip the missed dose. Do not take a double dose to compensate for the missed one.

Frequently Asked Questions (FAQs)

This medicine may be taken with or without food but preferably in the daytime and also at a fixed time to gain optimal benefits. You will be instructed by your doctor when and how to take Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone.

It is recommended to have a low fat and low salt diet. Perform regular and mild exercises Avoid drinking alcohol and smoking.

No, do not stop taking Olmesartan Medoxomil+Cilnidipine+Chlorthalidone / Chlortalidone suddenly as it may result in chest pain or a sudden rise in blood pressure.

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