Milnacipran

Molecule Description

Milnacipran is used in the treatment of chronic pain caused by Fibromyalgia alt

hough it works as an antidepressant.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Milnacipran

Chronic pain caused by Fibromyalgia (that affects the muscles, tendons, ligaments and supporting tissues)
Depression

Contraindications of Milnacipran

When should one not use Milnacipran

It is advisable to avoid taking Milnacipran in:
If you are allergic to this medicine
Child below 18 yrs of age
Kidney disease
Heart disease, high BP
Blood cell disorder e.g. sickle cell or haemophilia
Glaucoma
Low sodium levels in the body
Problems in urination
Bipolar disorder
Liver disorder
Convulsions or epilepsy

Side effects of Milnacipran

Common side effects of this drug are:

Nausea, vomiting
Dry mouth
Constipation
Increased sweating
Headache
Dizziness
Insomnia
High blood pressure
Serious side effects:
Allergic symptoms - itching, hives, rash, swelling of lips, face, etc.
Liver complaints – stomach pain, nausea, vomiting, jaundice, dark urine
Blurred vision, tunnel vision
Convulsion
Easy bruising, bleeding
Manic episodes – increased energy, extreme happiness, talkative etc.
High serotonin signs - hallucination, fever, agitation, nausea, vomiting, diarrhea, fainting, etc.
Low sodium signs – headache, confusion, slurred speech, loss of coordination, severe weakness, etc.
High BP – severe headache, chest pain, breathlessness, irregular heartbeats, nosebleed, etc.

Precautions and Warnings of Milnacipran

Pregnancy

Can I take Milnacipran during pregnancy?

It is advisable to avoid taking Milnacipran during pregnancy. It may affect the unborn baby.

Breast Feeding

Can I take Milnacipran while breastfeeding?

It is not recommended in breastfeeding. It is still not known if it passes into breast milk. Doctor's consultation is advised.

Driving

Can I drive if I have consumed Milnacipran?

It may impair your thinking or reactions and this in turn, may affect your ability to drive. Be cautious while driving if you are on this medication.

Alcohol

Can I consume alcohol with Milnacipran?

Milnacipran may cause excessive drowsiness and calmness with alcohol. It may worsen existing liver damage. It is advised to avoid excess intake of alcohol with this medicine.

Other General Warnings

Talk to your doctor if

You notice abrupt mood changes or develop suicidal thoughts
You have any liver, kidney or heart problems
You have any psychiatric conditions or you're on a medication for that

Mode of Action of Milnacipran

How Does It Work?

This medicine is Serotonin-Norepinephrine Reuptake Inhibitor (SNRI). It works by helping to restore the balance of certain natural substances present in the brain (neurotransmitters), thereby reducing...

Interactions of Milnacipran

Interactions with other medicines

Narcotic pain medicine, sleeping pills, muscle relaxants, medicine for anxiety, depression, fits, etc.
Certain medicine, when taken along with Milnacipran, can cause Serotonin syndrome – e.g., Medicine for Parkinson’s disease, migraine, ADHD, etc.
Blood thinners e.g., Warfarin

Interactions with food items

No adequate information.

Dosage of Milnacipran

Overdose

The symptoms of overdose can be – slow heart rate, weak pulse, fainting, slow breathing, etc.
Seek medical emergency help in case of overdose

Missed a Dose

If you miss a dose, take medicine when you remember the missed dose. If it is almost time for your next dose, don’t take the missed dose and go back to the regular dosing schedule. Do not take a doub...

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking Milnacipran?

Inform the doctor about your detailed medical & surgical history
Inform your physician if you have any of the following conditions -
Liver disease
Kidney disease
Heart disease, high BP
Blood cell disorder e.g. sickle cell or haemophilia
Glaucoma
Low sodium levels in the body
Problems in urination
If you drink alcohol
If you are taking blood thinners, e.g. warfarin
If you are pregnant, lactating or planning a pregnancy

Q: How is this medicine removed from the body?

A: About 58% of medicine is removed through urine.

Q: How long this medicine stays in the body after taking it?

A: Half-life of this medicine is around 8-10 hours; hence, it can stay up to 16-20 hours in the body.

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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