Metronidazole+Norfloxacin
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Molecule Summary
| Uses | Diarrhoea caused by mixed bacterial infections |
| Therapy | Antibacterial |
| Side Effects | Nausea, vomiting, constipation, indigestion |
Assurance
available
Regulated
Molecule Description
Metronidazole+Norfloxacin is a combination medicine containing norfloxacin and metronidazole as its active ingredients. It is used for the treatment of loose motions caused due to mixed bacterial infections.
Uses
Metronidazole+Norfloxacin is used for the treatment of loose motions caused due to mixed bacterial infections.
Contraindications
When should one not use Metronidazole+Norfloxacin
- If you are allergic to norfloxacin, metronidazole or any other ingredients of this medicine.
- If you have a known history of tendon rupture or tendinitis (develop swelling or pain in your limbs) associated with the use of norfloxacin or antimicrobial agents similar to it.
- If you have a condition of muscle weakness
- If you are known to have low immunity or ulcers or holes (perforations) in the gastrointestinal tract
- If you are pregnant or are breastfeeding.
- If you are suffering from a bacterial infection in the vagina.
Side effects
Common side effects of this drug are:
- Nausea
- Vomiting
- Constipation
- Indigestion
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You suffer from blood disorders (blood dyscrasias) or porphyria.
- You had or have a history of fits or epilepsy.
- You are pregnant or are breastfeeding.
- You experience infections after taking Metronidazole+Norfloxacin.
- You have peripheral neuropathy (abnormal, painful sensations like pins and needles).
- You have liver or kidney disease or are on dialysis.
- You are suffering from Cockayne syndrome (growth retardation, impaired development of the brain and sensitivity to sunlight).
- You are an alcoholic and must avoid alcohol during the treatment and for at least 48 hours after discontinuation of the treatment.
- You have tendon or nerve problems.
- You have problems with your heart like irregular heartbeats, abnormal heart rhythm and slow heartbeat.
- You have rheumatoid arthritis or a history of joint issues.
- You must avoid being in the sunlight for too long as this medicine may make you more sensitive to the sun.
Mode of Action
How Does It Work?
- Norfloxacin is an antibiotic that inhibits the production of the genetic material of bacteria. Thus, various substances essential for reproduction or survival of the bacteria cannot be produced by it. This affects their multiplication and they are ultimately killed.
- Metronidazole acts by stopping the growth of certain bacteria and parasites which are responsible for infection by interrupting the DNA and causing the DNA strands to break.
Interactions
Interactions with other medicines
- Some medicines can affect the way Metronidazole+Norfloxacin works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
Interactions with food items
Avoid alcohol during treatment and for at least 48 hours after treatment, as it can cause a disulfiram-like reaction (low blood pressure, hot flushes, nausea, shortness of breath).
Dosage
Overdose
- Symptoms of an overdose of Metronidazole+Norfloxacin include nausea, confusion, dizziness, seizures, etc. In case of overdose contact the doctor or reach out to the nearest hospital immediately.
Missed a Dose
If you missed any dose of this medicine, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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