Metoprolol+Hydrochlorothiazide

When should one not use Metoprolol+Hydrochlorothiazide

• If you are allergic to metoprolol, hydrochlorothiazide, or any other component of Metoprolol+Hydrochlorothiazide
• If you have heart disease
• If you suffer from a lung condition that narrows or tightens the airways, making it difficult to breathe
• If you have a tumour in your adrenal gland
• If you have major surgery scheduled
• If you are diabetic
• If you have thyrotoxicosis
• If you are using calcium channel blockers
• If you have kidney or liver disease
• If you are short-sighted and have a type of eye pressure problem known as secondary angle-closure glaucoma
• If you have lupus
• If you are taking lithium

Common side effects of this drug are:

• Slow heart rate
• Tiredness
• Low potassium
• Inflammation of the pancreas

Other General Warnings

• You experience an allergic reaction after taking this medicine.
• You have medical conditions such as diabetes, heart disease, liver disease, or kidney disease.
• You have respiratory conditions like asthma or chronic obstructive pulmonary disease (COPD).
• You are pregnant, planning a pregnancy, or breastfeeding.
• You have a tumour of the adrenal gland tissue (Pheochromocytoma).
• You have an overactive thyroid (when the thyroid gland produces too much thyroxine).
• You have psoriasis (a type of skin disease).
• You have circulation-related problems in the toes, arms, legs, or fingers.
• You are suffering from a type of chest pain (Prinzmetal's angina).
• You recently had a heart attack, chest pain, or heart surgery.
• You are under 18 years of age.
• You are already taking blood pressure-lowering medicine.
• You have an autoimmune disorder called systemic lupus erythematosus.
• You are dehydrated or experiencing excessive urination, vomiting, or diarrhoea.
• You are diabetic and taking anti-diabetic medicine or insulin.
• This medicine may cause salt or electrolyte imbalance, so patients should be monitored closely.
• This medicine may interfere with laboratory test results, so inform your doctor or lab personnel.

How Does It Work?

Interactions with other medicines

• Medicines used to treat irregular heart rhythm (Amiodarone, disopyramide)
• Medicines used to treat pain or inflammation (Indomethacin, Sulindac, Diclofenac and Foctafenine)
• Medicines used to treat depression (Fluoxetine, Paroxetine and Bupropion)
• Medicines used to treat mental conditions (antipsychotic) like Thioridazine
• Medicines used to treat HIV (antiretroviral) like Ritonavir
• Medicines used to treat allergies (antihistamines) like Diphenhydramine
• Medicines used to treat malaria (Hydroxychloroquine, Mefloquine)
• Medicines used to treat fungal infections of the skin (Terbinafine)
• Medicines used to treat acidity or ulcers (antacids) like Cimetidine
• Medicines used to treat heart problems (Digoxin)
• Medicine used in acute shock and severe allergic reaction (Epinephrine)
• Medicine used to reduce swelling of the nose (Phenylpropanolamine)
• Medicines used to treat depression and Parkinson's disease (Monoamine Oxidase inhibitors)
• Medicines used to lower the blood pressure (Clonidine, Guanfacine, Moxonidine, Methyldopa, Rilmenidine)
• Medicines used to treat migraine (Ergotamine, Non-steroidal Anti-inflammatory Drugs)
• Medicines used to treat chest pain (Nitroglycerine)
• General anaesthetics or local anesthetic (Lidocaine)
• Medicines used to reduce blood sugar level like Insulin and oral antidiabetic medicines
• Medicines used to treat high blood pressure and benign prostatic hyperplasia (Prazosine, Tamsulosin, Terazosin, Doxazosin)
• Medicines used to treat tuberculosis (Rifampicin)
• Medicines such as barbiturates, narcotics, corticosteroids, muscle relaxants can also interact with this medicine
• Lithium and diuretics can interact negatively. Diuretics increase the risk of lithium toxicity by reducing the kidneys' ability to eliminate lithium. When taken together, this can lead to higher levels of lithium in the blood, which may result in adverse effects or toxicity. Therefore, it is generally advised to avoid using lithium in conjunction with diuretics to minimise this risk.

Interactions with food items

• You can prevent low potassium levels by eating foods that are rich in potassium.

Overdose

• Signs of a Metoprolol+Hydrochlorothiazide overdose include a slow heart rate, low blood pressure, and drowsiness. In severe cases, it may lead to confusion, coma, seizures, and respiratory failure. Heart failure, breathing difficulties, and low blood sugar can occur, particularly in individuals with other health issues. Rarely, Metoprolol+Hydrochlorothiazide overdoses result in a loss of excessive fluids and electrolytes. Symptoms may include a rapid heart rate, low blood pressure, muscle weakness, confusion, dizziness, fatigue, nausea, and changes in urine output.
• If you believe you have taken too much Metoprolol+Hydrochlorothiazide, contact your doctor immediately or visit the nearest hospital.

Missed a Dose