Follicle Stimulating Hormone (Fsh)

Uses	Female infertility
Therapy	Drugs For Female Infertility
Side Effects	Nausea, vomiting, stomach pain, headache

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Molecule Description

Follicle Stimulating Hormone (Fsh) is a fertility medicine that is used in the treatment of female infertility. It is used to stimulate the ovaries. This may increase the chance of pregnancy. It contains Urofollitropin as its active ingredient which is a purified form of a hormone called follicle-stimulating hormone (FSH).

Uses

To treat infertility in women with FSH deficiency.
It is also used to help the ovaries produce multiple eggs for use in "in-vitro" fertilization or Assisted reproductive technologies (ART)

Contraindications

When should one not use Follicle Stimulating Hormone (Fsh)

If you are allergic to urofollitropin or any of the other ingredients of this medicine.
If you have a high level of LH and FSH hormones.
If you have a thyroid problem or adrenal dysfunction (a disorder in which the adrenal glands don't produce enough hormones).
If you have a tumour in the brain.
If you have a cyst in the ovaries.
If you have any cause of infertility other than anovulation (when an egg doesn't release from your ovary during menses).

Side effects

Common side effects of this drug are:

Pain, irritation, swelling, redness at the site of injection
Nausea
Vomiting
Stomach ache
Headache

Precautions and Warnings

Pregnancy

It is not safe for pregnant women and may cause fetal harm when administered to a pregnant woman.

Breast Feeding

There is limited safety data available about the use of this medicine in breastfeeding mothers. Hence, it is very important to inform your doctor before starting the treatment while breastfeeding.

Driving

It is not expected that Follicle Stimulating Hormone (Fsh) will affect your ability to drive, but if you do not feel well or are unable to be alert, then avoid driving.

Alcohol

There is limited information about the effects of Follicle Stimulating Hormone (Fsh) on alcohol, but avoid taking alcohol in excessive amounts.

Other General Warnings

Talk to your doctor if

You had experience with infertility problems. Such patients can have mild adverse effects and should be carefully monitored during the treatment.
You may experience ovarian enlargement along with extended stomach and stomach pain. To prevent this minimum effective dose of this medicine should be used and cautious monitoring of ovarian reaction is required.
You may develop the risk of Ovarian Hyper-Stimulation Syndrome (OHSS). The symptoms may include lower abdominal pain, breathing difficulty, rapid weight gain, nausea etc. If you experience any of such symptoms, talk to your doctor it may require discontinuation of treatment.
You may have a higher risk of being pregnant with more than one child at the same time (multiple pregnancies).

Mode of Action

How Does It Work?

Urofollitropin is a purified form of a hormone called follicle-stimulating hormone (FSH). This hormone is important in the development of follicles (eggs) that are produced by the ovaries in women. It helps in improving reproductive function by facilitating the release of eggs in females and thus increases the chances of pregnancy.

Interactions

Interactions with other medicines

Follicle Stimulating Hormone (Fsh) may interact with other medicines and discuss with your doctor about all the medicines, supplements or herbal preparations you are taking. Also, inform your doctor if you have a planned surgery or vaccination scheduled.
Especially if you are taking any other medicines used in the treatment of female infertility, as it may increase the effect on ovaries.

Dosage

Overdose

The doctor or nurse usually gives this medicine, so the chances of overdose are less because the treatment and the dose will be specific to the patient. However, in case of any discomfort after or during the treatment with this medicine, they should be informed immediately to the doctor.

Missed a Dose

The doctor or nurse usually gives Follicle Stimulating Hormone (Fsh) in the hospital or a clinic. Therefore, the chances of missing a dose are less. However, if you feel that a dose has been missed, then please inform your doctor and nurse.

Frequently Asked Questions (FAQs)

Follicle Stimulating Hormone (Fsh) is used in the treatment of female infertility. It is used in women who have a problem with ovulation or are undergoing fertility treatments like in-vitro fertilization. Follicle Stimulating Hormone (Fsh) is used together with other medicines to treat infertility in women with FSH deficiency. It is also used to help the ovaries produce multiple eggs for use in "in-vitro" fertilization or Assisted reproductive technologies (ART).

No, it is not for use in males.

No, it is not recommended for use in pregnant women.

Yes, the treatment with Follicle Stimulating Hormone (Fsh) is more likely to result in multiple pregnancies (twins or more). The patient and her husband should be informed of the potential risk of multiple births before starting therapy.

Ovarian hyperstimulation syndrome (OHSS) is a condition when a woman's ovaries swell and leak fluid into the body. Early symptoms of the OHSS are severe pelvic pain, nausea, vomiting, and weight gain. OHSS generally resolves with the onset of menses.

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