Esomeprazole+Levosulpiride

Uses	GERD Treatment of ulcers of stomach and intestine
Therapy	Antacid And Anti-Reflux
Side Effects	Headache, nausea, vomiting, pain in the abdomen

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Molecule Description

Esomeprazole+Levosulpiride contains a combination of esomeprazole and levosulpiride as active ingredients. It is an anti-reflux medicine that is used for the treatment of gastroesophageal reflux disease (GERD). GERD is a condition when the acid from the stomach comes up to the food pipe along with the contents of the stomach and causes heartburn, chest pain, burning, pain and regurgitation of food or sour liquid. Esomeprazole+Levosulpiride is also useful in the treatment of stomach and intestinal ulcers. It blocks the acid-producing pumps of stomach cells. Tell your doctor if you have an abnormal heart rhythm or take medicines for other mental illnesses. Take it at the exact dose prescribed by your doctor. Inform your doctor if you get allergic reactions or if symptoms don't improve after using it. Before using Esomeprazole+Levosulpiride, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.

Uses

For the treatment of the condition known as gastroesophageal reflux disease (GERD). It is also used to treat the stomach and intestinal ulcers.

Contraindications

When should one not use Esomeprazole+Levosulpiride

If you are allergic to esomeprazole, levosulpiride or any other ingredients of Esomeprazole+Levosulpiride. If you are taking other medicines like Nelfinavir (for HIV infection). If you have fits. If you have mood disorders or any other mental illness. If you have breast cancer. If you have high blood pressure due to pheochromocytoma (tumour of the adrenal gland).

Side effects

Common side effects of this drug are:

Headache
Pain in the abdomen
Nausea and Vomiting
Altered bowel movements
Anxiety
Confusion

Precautions and Warnings

Pregnancy

Do not take this medicine if you are pregnant or planning to have a baby. After careful clinical examination and evaluation of the risk-benefit ratio, your doctor may prescribe you this medicine.

Breast Feeding

This medicine may pass into breast milk and adversely affect your baby. So, do not use this medicine without a doctors advice.

Driving

You may experience numbness, dizziness or involuntary movements during treatment with this medicine so avoid driving or using heavy machinery if you experience any of the side effects.

Alcohol

No, consumption of alcohol is not recommended as it increases the chances of dizziness and liver damage.

Other General Warnings

Talk to your doctor if

You have severe liver problems.
You have severe kidney problems.
You have a history of allergy or skin reaction with any other anti-acidity medicine.
You are due to have a specific blood test (Chromogranin A).
You have osteoporosis.
You are taking medicines like corticosteroids (it increases the risk of osteoporosis).
You get a rash on the skin, especially in areas exposed to the sun.
You have any gastric bleeding, mechanical obstruction or perforation in the digestive tract.
You experience dementia (loss of memory).
You have a history of strokes.
You have any condition related to heart and circulation, or abnormal heart rhythm (QT prolongation).
You have a history of blood clotting or a family history of it.
You are taking medicines for other mental illnesses.
This medicine may hide the symptoms of other diseases so if you experience symptoms like losing a lot of weight without any reason, stomach pain and indigestion, repeated vomiting, swallowing problems, blood in vomit or passing black stool then talk to your doctor immediately or if the symptoms don't improve or change the character.

Mode of Action

How Does It Work?

In the stomach, there are special cells which produce acid for digestion. When there is overproduction of this acid, it becomes harmful as it is responsible to produce ulcers in the stomach and intestine.
Esomeprazole blocks these small acid-producing pumps in the stomach cells and helps in reducing acidity and promotes healing of those ulcers.
Levosulpiride increases the forward propulsive movement of the digestive tract by releasing a few chemicals and helps to relieve the symptoms of GERD like heartburn and reflux of food.

Interactions

Interactions with other medicines

Esomeprazole+Levosulpiride may interact with other medicines, discuss with your doctor about all the medicines, supplements or herbal preparations you are taking.
Especially, if you are taking anti-fungal medicines, anti-HIV medicines or medicines for brain and heart-related disorders, etc.
Antacids & medicines used to treat ulcers, such as sucralfate, should be taken with at least 2 hours of gap.
Your blood pressure may drop if you are taking antihypertensive medicine along with this medicine. Caution is advised.

Interactions with food items

It is advisable to avoid spicy, oily, or fried foods as they can exacerbate symptoms of GERD and may interfere with the medication's effectiveness.

Dosage

Overdose

If you think you have taken too much of this medicine contact your doctor immediately or visit the nearest hospital. Overdose of this medicine may increase the chances of side effects like tremors, difficulty and slow movements or sleep problems.

Missed a Dose

If you forget a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose. Do not stop taking this medicine without doctor's advice, as this may result in flare up of symptoms.

Frequently Asked Questions (FAQs)

Esomeprazole+Levosulpiride is used in gastroesophageal reflux disease and peptic ulcer (ulcers in stomach or intestine).

Esomeprazole+Levosulpiride contains medicine known as Esomeprazole and Levosulpiride. Esomeprazole blocks the small acid producing pumps in the stomach cells and helps in reducing acidity and promotes healing of those ulcers. Levosulpiride increases the forward propulsive movement of digestive tract by releasing few chemicals and helps to relieve the symptoms of GERD like heartburn and reflux of food.

Take Esomeprazole+Levosulpiride as advised by your doctor. Usually, you should take this medicine at least 30- 40 mins before food, preferably in the morning before breakfast.

Esomeprazole+Domperidone contains a combination of two medicines- domperidone and esomeprazole. Esomeprazole+Levosulpiride contains a combination of two medicines- levosulpiride and esomeprazole.

Yes, Esomeprazole+Levosulpiride can sometimes cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and also avoid driving and lifting any heavy object.

Stomach aches can be due to various reasons. Esomeprazole+Levosulpiride can provide some relief from stomach aches if it is associated with stomach or intestinal ulcers or due to acidity.

Esomeprazole+Levosulpiride is used for the treatment of the condition known as gastroesophageal reflux disease (GERD). It is also used to treat stomach and intestinal ulcers. Do not use this medicine for any other medical condition other than what it is prescribed for. Do not self-medicate. Hence you should consult a doctor before taking this medicine for IBS (irritable bowel syndrome) condition.

Both are antacid medicines but have different compositions. Esomeprazole+Levosulpiride contains esomeprazole and levosulpiride, while Pantoprazole+Domperidone contains pantoprazole and domperidone as active ingredients. You should take the prescribed medicine only. Refrain from self-medication.

Headache, nausea, vomiting, and pain in the abdomen are a few side effects of Esomeprazole+Levosulpiride. However, these symptoms are usually mild and resolve on your own. Also, everyone doesn't have to experience the same.

The dose and frequency of Esomeprazole+Levosulpiride vary among individuals depending on the condition it is being taken for. You should not consume more than the recommended daily dose by the doctor.

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