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Epalrestat

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Molecule Summary

Uses
Decreases Cholesterol Absorption, Dissolves Cholesterol Gallstones
Therapy
Drugs For Diabetic Neuropathy
Side Effects
Diarrhoea, High Creatinine, High Blood Sugar, Peptic Ulcer, Skin Rash
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Molecule Description

This medicine is a carboxylic acid derivative. It belongs to a group of medicines called 'reversible aldose reductase inhibitor' used for the treatment of diabetic neuropathy.

Uses

To treat nerve damage due to diabetes mellitus

Contraindications

When should one not use Epalrestat

  • Allergy to this medicine
  • Severe liver insufficiency

Side effects

Common side effects of this drug are:

  • Stomach discomfort
  • Nausea
  • Diarrhea
  • Abdominal pain
  • Allergic skin rash and itching

Precautions and Warnings

Pregnancy

Pregnancy

There are no adequate studies available. It is not recommended to use this medicine during pregnancy. Do not take this medicine without doctor’s advice.

Breast Feeding

Breast Feeding

No adequate studies available. It is not recommended to use this medicine during breastfeeding. Do not take this medicine without doctor’s advice.

Driving

Driving

No specific information available

Alcohol

Alcohol

No specific information available about interactions of this medicine with alcohol.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • Tell your doctor if:
  • You experience any discomfort, rashes, swelling after taking this medicine
  • About all your medical conditions and ongoing medications

Mode of Action

How Does It Work?

It suppresses the accumulation of sorbitol in nerve by inhibiting aldose reductase. It relieves numbness/ pain of the hands, feet, leg cramps, etc. which are the commonly experienced complications of diabetes.

Interactions

Interactions with other medicines

No specific data available for medicine interactions

Interactions with food items

No information is available on interactions of this medicine when taken with food, consult your doctor or pharmacist for further information.

Dosage

Overdose

Seek emergency medical attention or poison help if you think you have used too much of this medicine. Overdose symptoms have not been reported well in scientific literature.

Missed a Dose

If you missed any dose, take it as early as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of medicine to compensate for a missed one.

Frequently Asked Questions (FAQs)

Give a detailed account of your medical and surgical history. Also, mention to your doctor all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.

Take this medicine orally with a glass of water exactly as directed by your doctor. Follow the instructions given on the prescription label.

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References:

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