Efonidipine

Uses	High blood pressure
Therapy	Anti-Hypertensive
Side Effects	Headache, palpitation, flushing of face, hot flushes

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Molecule Description

Efonidipine is an anti-hypertensive medicine. It is used for the treatment of high blood pressure. It can also be used for the treatment of angina, a type of chest pain caused by the reduced blood supply to the heart. It works by widening the blood vessel by relaxing the wall of blood vessels. Due to the widening of blood vessels, blood passes through them more easily which further decreases blood pressure. It also works by excretion of sodium through urine. It also relieves chest pain by improving blood supply to the heart muscle. Heart muscle receives more oxygen due to improvement in the blood supply. Headache, palpitation (feeling of heartbeat), flushing of the face, hot flushes are common side effects of this medicine. If side effects do not go away on their own or your condition doesn't improve over time then inform your doctor.

Uses

It is used for the treatment of high blood pressure. It can also be used for the treatment of angina, a type of chest pain caused by the reduced blood supply to the heart.

Contraindications

When should one not use Efonidipine

If you are allergic to Efonidipine or any other ingredients of this medicine.
If you are pregnant.

Side effects

Common side effects of this drug are:

Headache
Palpitation
Flushing of face
Hot flushes

Precautions and Warnings

Pregnancy

Limited information is available on the safety of this medicine in pregnancy. Use in pregnant women is not recommended.

Breast Feeding

It is not known whether components of this medicine pass into breast milk. This medicine should not be taken by lactating mothers.

Driving

This medicine can cause dizziness. Avoid driving if you have dizziness after taking this medicine.

Alcohol

Consumption of alcohol with this medicine can interfere with the working of this medicine and also increases the side effects of this medicine. Avoid alcohol consumption if you are taking this medicine.

Other General Warnings

Talk to your doctor if

You have liver disease.
You have a severe increase in your blood pressure.
You have heart failure.
You have a heart attack recently.
You have low blood pressure.

Mode of Action

How Does It Work?

It works by widening blood vessels by relaxing the walls of blood vessels. Due to the widening of blood vessels, blood passes through them more easily which further decreases blood pressure. It also works by excretion of sodium through urine. It also relieves chest pain by improving blood supply to the heart muscle. Heart muscle receives more oxygen due to an improvement in blood supply.

Interactions

Interactions with other medicines

Concomitant use of Efonidipine with other anti-hypertensive medicines can cause a further decrease in blood pressure.
Concomitant use of cimetidine (used to reduce stomach acid) with Efonidipine can cause an increased blood level of efonidipine.
Concomitant use of Efonidipine with tacrolimus can cause an increased blood level of tacrolimus.
Discuss with your doctor any other medicine, herbal preparation, and supplements you are taking currently to avoid any possible interactions.

Interactions with food items

Grapefruit juice or grapefruit can cause an increase in the blood level of Efonidipine.

Dosage

Overdose

Symptoms of overdose include dizziness, fainting, redness of skin etc. If you have taken too much of this medicine then contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you have missed taking any dose of this medicine then take it as soon as you remember. If it's already time for the next dose then skip the missed dose and follow the regular dosing schedule.

Frequently Asked Questions (FAQs)

Efonidipine can cause flushing of the face as a side effect. Flushing of the face is caused due to widening of superficial blood vessels of the face due to this medicine.

Efonidipine should be taken in dose and duration as advised by your doctor. If you stop taking Efonidipine, your blood pressure may rise again. If your blood pressure is under control with this medicine without any side effects you can take Efonidipine until your doctor tells you to stop.

Efonidipine is prescribed to you by your doctor for high blood pressure. Along with medication, certain lifestyle changes should be adopted such as reduced salt intake, daily routine exercise such as walking, diet low in saturated fatty acid etc.

If your blood pressure becomes lower than normal blood pressure after taking Efonidipine, the dose reduction of this medicine is needed. Consult your doctor immediately for further management.

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