Disodium Hydrogen Citrate

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Molecule Description

Disodium Hydrogen Citrate is a medicine used to treat kidney stones, gout, urinary tract infections, and other conditions caused by high uric acid levels. It works by making your urine less acidic, which helps dissolve uric acid and other substances that can form stones or crystals in the urinary tract. This makes it easier for your body to flush these substances out through urine, preventing new stones from forming and easing symptoms such as burning or pain during urination. To get the best results, it should be taken exactly as prescribed by your doctor, usually after meals, and it is important to drink plenty of water while on this medicine. Patients with kidney, heart, or lung conditions, or those on a low-sodium or low-potassium diet, should consult their doctor before using it.

Uses

Disodium Hydrogen Citrate is used to treat gout (increased uric acid levels) and kidney stones.
It is also used to treat urinary tract infections and metabolic disorders associated with kidney disease.

Contraindications

When should one not use Disodium Hydrogen Citrate

If you are allergic to Disodium Hydrogen Citrate.
If you have kidney diseases.
If you have high sodium or potassium levels.
If you have high blood pressure, irregular heartbeats, or heart failure.
If you have low calcium levels.
If you have lung diseases.
If you have diabetes.
If you have Addison's disease (an adrenal gland disorder).

Side effects

Common side effects of this drug are:

Stomach pain
Weakness
Nausea
Vomiting
Diarrhoea

Precautions and Warnings

Pregnancy

There is limited information available on the use of Disodium Hydrogen Citrate during pregnancy. It is recommended not to use it during pregnancy, unless advised by a doctor.

Breast Feeding

Disodium Hydrogen Citrate may cause some adverse effects on the baby. Hence, this medicine is not advised during breastfeeding.

Driving

Disodium Hydrogen Citrate does not affect your driving ability. However, if you experience any discomfort or side effects, then avoid driving.

Alcohol

This medicine can cause dehydration, and the consumption of alcohol can increase the risk of dehydration. Hence, it is recommended to avoid consuming alcohol while taking Disodium Hydrogen Citrate.

Other General Warnings

Talk to your doctor if

You are diabetic.
You have a kidney disease.
You are suffering from chronic diarrhoea (such as ulcerative colitis and Crohn's disease).
Do not alter the dose of Disodium Hydrogen Citrate by yourself.
Take this medicine with food for better absorption and to help prevent stomach-related side effects.

Mode of Action

How Does It Work?

Disodium hydrogen citrate is metabolised to bicarbonates. These bicarbonate ions are excreted in the urine by increasing the urinary pH. This increase in pH makes the urine less acidic. This increase in urinary pH helps remove excess uric acid.

Interactions

Interactions with other medicines

May interact with other medicines, over-the-counter products, and herbal preparations, potentially altering their effects.
Antacids containing aluminium and magnesium should be taken at least two hours after this medicine.
May interact with Aspirin.
Other medicines that can interact include Lithium, Quinidine, and Salicylates.

Dosage

Overdose

If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed a dose of the medicine, take it as soon as you remember. If it is time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

Frequently Asked Questions (FAQs)

Disodium Hydrogen Citrate is used to treat kidney stones, gout, urinary tract infections, and other conditions caused by high uric acid levels. It helps make urine less acidic, which dissolves uric acid and other substances that can form stones or crystals.

It makes your urine more alkaline, helping dissolve uric acid and other crystals so they can be flushed out of the body, preventing new stone formation and easing urinary discomfort.

No, do not stop the medicine without your doctor’s advice, as this may worsen your condition or lead to recurrence of kidney stones.

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