Chlorpheniramine / Chlorphenamine+Diethylcarbamazine

Uses	Parasitic and worm infections
Therapy	Anthelmintic
Side Effects	Drowsiness, fits, improper coordination, dizziness, headache

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Molecule Description

Chlorpheniramine / Chlorphenamine+Diethylcarbamazine is a combination medicine used in the treatment of various parasitic infections. It also helps in relieving allergic symptoms like rashes, swelling, itching and watering from eyes associated with the disease. It contains two active components namely diethylcarbamazine and chlorpheniramine maleate that belongs to a different class of medicines called antiparasitic and antihistaminic respectively. Use the exact dose prescribed by your doctor. Please do not modify the dose or stop it before the prescribed duration, even if you feel better. In case of any unusual observation, contact your physician immediately.

Uses

It is used in the treatment of different parasitic infections like lymphatic filariasis (parasite worms that affect the lymphatic system), loiasis and onchocerciasis. It also relieves allergic reactions like redness, itching, watering from eyes, swelling of lips, and face.

Contraindications

When should one not use Chlorpheniramine / Chlorphenamine+Diethylcarbamazine

If you have a history of allergy to Chlorpheniramine / Chlorphenamine+Diethylcarbamazine or any of the content of the medicine.
If you have bleeding problems.
If you have any kind of eye infection.
If you have recently taken any medicines to treat brain-related disorders, in the last two weeks.
If you are taking other medicines containing other antihistamines, for the relief of colds and coughs.

Side effects

Common side effects of this drug are:

Drowsiness
Fits
Improper coordination
Dizziness
Headache
Feeling or being sick
Dry mouth
Fatigue
Breathlessness
Low output of urine

Precautions and Warnings

Pregnancy

This medicine may pass into the blood of the baby and may produce side effects so take a doctor's advice before taking this medicine if you are pregnant or planning to have a baby.

Breast Feeding

This medicine may pass into the breast milk and adversely affect your baby so do not take this medicine without doctor's advice if you are breastfeeding your baby.

Driving

This medicine may produce drowsiness and affect your ability to drive or use heavy machines so do not get involved in any activities which require alertness.

Alcohol

No, this medicine may produce drowsiness and liver damage if you take it with alcohol.

Other General Warnings

Talk to your doctor if

You are having any kind of underlying medical condition like liver or kidney problems, heart disorders, hypertension, fits, respiratory problem etc.
You are having glaucoma (increased pressure in the eye).
You are having an enlarged prostate or difficulty in passing urine.
Do not use it continuously for more than 14 days without consulting your doctor.
Do not give to children under 6 years of age.

Mode of Action

How Does It Work?

The parasite also has its metabolic process, growth and multiplication. Diethylcarbamazine alters the metabolic process in the filarial cells, which makes them more prone to killing by the human defence system. Thus it helps in killing the parasite and eradicate the infection.
The killing of filarial cell releases certain chemicals (histamine), which produces allergic symptoms like skin redness, itching, swelling and watering from the eyes. Chlorpheniramine Maleate is an antihistaminic medicine, which blocks the effect of histamine and relieves the allergic symptoms associated with it.

Interactions

Interactions with other medicines

Certain medicines can interfere with the action of Chlorpheniramine / Chlorphenamine+Diethylcarbamazine or Chlorpheniramine / Chlorphenamine+Diethylcarbamazine itself can affect the action of other medicines taken at the same time.
Always inform your doctor about all the medicine you are taking, that includes all prescribed or non-prescribed herbal medicines, dietary supplements as well as other treatment if you are taking for any disorder.
Especially if you are on certain medications like antiepileptic medicines, medicines for anxiety or to help you sleep, medicines for brain-related disorders or other medicines containing antihistamines.

Dosage

Overdose

If you think you have taken too much of this medicine contact your doctor immediately or visit the nearest hospital. Overdose of this medicine may increase the chances of side effects.

Missed a Dose

If you forget a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose. Do not stop taking this medicine without the doctor's advice, as this may result in a flare-up of symptoms.

Frequently Asked Questions (FAQs)

Chlorpheniramine / Chlorphenamine+Diethylcarbamazine is used in the treatment of different parasitic infections like lymphatic filariasis, loiasis and onchocerciasis. It also relieves allergic reactions like redness, itching, watering from eyes, swelling of lips, and face.

Chlorpheniramine / Chlorphenamine+Diethylcarbamazine contains medicines known as Diethylcarbamazine and Chlorpheniramine Maleate. Diethylcarbamazine alters the metabolic process in the filarial cells, which makes them more prone to killing by the human defence system. Thus it helps in killing the parasite and eradicate the infection. The killing of filarial cell releases certain chemicals (histamine), which produces allergic symptoms like skin redness, itching, swelling and watering from the eyes. Chlorpheniramine Maleate is an antihistaminic medicine, which blocks the effect of histamine and relieves allergic symptoms like rashes, swelling, itching and watering from eyes associated with it.

Do not take it with other medicines without asking your doctor, as some medicines can increase the chances of side effects. Inform your doctor about all the medicine you are taking especially if you are taking medicines for brain-related diseases, other antihistamine medicines, medicines for fits, anxiety or sleeping problems.

Stop taking this medicine and contact your doctor if you experience any abnormal symptoms during the treatment. Do not use it continuously for more than 14 days without consulting your doctor. Do not stop taking this medicine by yourself as it may increase the chances of symptoms coming back.