Chlorzoxazone+Diclofenac Sodium+Paracetamol / Acetaminophen

• Chlorzoxazone+Diclofenac Sodium+Paracetamol / Acetaminophen is used to relieve pain and inflammation in muscles, joints, and bones in conditions such as arthritis, spondylitis, and injuries.
• It is also used for relieving pain, inflammation and swelling post-surgeries and operations.

When should one not use Chlorzoxazone+Diclofenac Sodium+Paracetamol / Acetaminophen

• If you are allergic to diclofenac, paracetamol, chlorzoxazone or any ingredient of Chlorzoxazone+Diclofenac Sodium+Paracetamol / Acetaminophen.
• If you are experiencing bleeding from the stomach and intestine, or have an active peptic ulcer.
• If you are allergic to other painkillers such as aspirin and have experienced severe asthma, rashes or any other allergy.
• If you have severe heart failure.
• If you have severe kidney or liver problems.
• If you are pregnant.
• This medicine should not be used for relieving pain before, during and after heart bypass surgery.

Common side effects of this drug are:

• Dizziness
• Lightheadedness
• Nausea
• Vomiting
• Weakness
• Fatigue
• Liver problem
• Headache
• Rash

Other General Warnings

• You have kidney or liver problems.
• You have heart problems like high blood pressure, heart failure.
• You are an elderly patient or taking diuretics or have a kidney disorder, this medicine can increase the risk of kidney failure.
• Your doctor may ask you to undergo renal function tests for this purpose.
• You are suffering from gastrointestinal problems like bleeding, ulcers in the intestine (perforation) or Crohn's disease or you are passing black tarry stools.
• You have asthma as this medicine can worsen the same.
• You have Systemic lupus erythematosus (SLE), an autoimmune disorder.
• You are an alcoholic, so concomitant use of this medicine can damage the liver.
• You have disorders related to blood like clotting problems and anaemia.
• You have skin rashes & lesions after taking this medicine.

How Does It Work?

Interactions with other medicines

• Do not take any other medicines containing Paracetamol or Diclofenac as there is a risk of liver damage.
• If you are taking medicines for high blood pressure, this medicine can interfere with their effect.
• Medicines like water pills can lead to kidney damage when taken along with it.
• Caution is needed if you are taking medicines to treat heart failure.
• This medicine can increase the levels of lithium and methotrexate. Discuss with your doctor before starting the treatment.
• Medicines used to modify immune response during organ transplant like ciclosporin & tacrolimus can result in kidney damage if taken with this medicine.
• Increased risk of stomach ulcers or bleeding when taken with steroids or other pain relief medicines like Aspirin.
• There is a risk of bleeding if you are taking blood-thinning medicines like Warfarin and Coumarin.
• Increased risk of fits if you are taking this medicine with antibiotics like Levofloxacin and Ciprofloxacin.
• If you are taking medicines to treat diabetes, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat and hunger pangs.
• Medicines used to treat fits, seizures & depression-like Phenobarbital, Carbamazepine, Phenytoin and Clonazepam should be used with caution as this medicine can increase the side effects of these medicines.
• Medicine used to treat gout-like Probenecid, medicines used to treat a bacterial infection like Chloramphenicol, Rifampicin and HIV infections like Zidovudine should be used cautiously.

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