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Celecoxib

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Molecule Summary

Uses
Rheumatoid Arthritis, osteoarthritis, acute pain
Therapy
Drugs For Osteoarthritis, Drugs For Rheumatoid Arthritis
Side Effects
Headache, dizziness, nausea, vomiting, stomach pain
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Molecule Description

Celecoxib is used for relieving pain, swelling and inflammation associated with muscles, joints and bones. It is an anti-inflammatory medicine. This medicine works by interfering with the action of prostaglandins, a chemical responsible for pain, swelling and inflammation in the body. It is used for the short-term treatment of pain in adults and should not be used in children. Celecoxib should be taken as directed by the doctor and in doses and duration as prescribed. It can be taken with or without food.

Uses

  • Celecoxib is used for relieving pain, swelling and inflammation associated with musculoskeletal disorders such as arthritis, muscle spasm, menstrual cramps, etc.
  • It is also used for the short-term treatment of acute pain.

Contraindications

When should one not use Celecoxib

  • If you are allergic to celecoxib or any of the ingredients of Celecoxib
  • If you are allergic to sulfonamides class of medicines
  • If you are suffering from peptic ulcer or gastrointestinal bleeding
  • If you have severe kidney or liver disease, inflammatory bowel disease (intestine disease) or serious heart problems
  • If you experienced any side effect like wheezing, asthma after taking any other pain medications like aspirin and Ibuprofen in the past
  • If you are pregnant or breastfeeding

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Constipation
  • High blood pressure

Precautions and Warnings

Pregnancy

Pregnancy

Celecoxib should not be taken during pregnancy. If a woman becomes pregnant during treatment, this medicine must be discontinued. If you are pregnant, think you can be pregnant or are planning a pregnancy consult your doctor before using this medicine.

Breast Feeding

Breast Feeding

It is unknown if celecoxib passes into the breastmilk. Thus, you should not breastfeed while taking Celecoxib. Please contact your doctor before using it.

Driving

Driving

Celecoxib can cause dizziness, spinning sensation (vertigo) or sleepiness. If you experience any of these effects, do not drive or operate machines.

Alcohol

Alcohol

You should avoid consuming alcohol while taking Celecoxib as it can worsen the side effects like dizziness.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are pregnant or breastfeeding.
  • You are an aged person (above 65 years).
  • You are suffering from liver disease or kidney disease.
  • You are suffering from vomiting or diarrhoea and are dehydrated.
  • You have swelling due to fluid retention (excess fluid in the body).
  • You have a history of heart failure or other diseases related to the heart.
  • You have high blood pressure. Your doctor may need to check your blood pressure more often.
  • You are a diabetic, smoker or have high cholesterol as all these increases the chance of heart disease.

Mode of Action

How Does It Work?

Prostaglandins are chemicals produced at the site of injury or damage where they cause pain, swelling and inflammation as a part of the natural healing process of the body. Celecoxib works by reducing the formation of Prostaglandins.

Interactions

Interactions with other medicines

  • Celecoxib can interact with other medicines taken at the same time and produce an altered response. Tell your doctor about all the medicines, herbals or supplements you are taking or might take.
  • In particular, if you are taking blood-thinning medicines, certain anti-infectives, immunomodulators, high blood pressure medicines, medicines for treating uneven heart rate, anti-asthmatics, oral contraceptives, certain hormonal preparation, etc.

Interactions with food items

Celecoxib can be taken with or without food.

Dosage

Overdose

If you think you have taken too much of Celecoxib, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

  • If you missed any dose, take it as soon as you remember.
  • If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
  • Do not take a double dose of medicine to compensate for a missed one.

Frequently Asked Questions (FAQs)

Inform your doctor if you have any infection because this medicine can mask the symptoms of a severe infection. Tell your doctor about your complete medical and medication history. Also, if you are pregnant or breastfeeding.

Celecoxib should not be used during pregnancy or should be discontinued if pregnancy is detected while on treatment with Celecoxib. It can delay the labour and can lead to malformations in the growing foetus.

Celecoxib is used to relieve pain, swelling and inflammation associated with musculoskeletal disorders such as arthritis, muscle spasm, menstrual cramps, etc. It is also used for the short-term treatment of acute pain.

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