Cefuroxime+Clavulanic Acid

Uses	Bacterial infections
Therapy	Antibiotic
Side Effects	Diarrhoea, nausea, vomiting, stomach pain, flatulence, indigestion, headache, vaginal itching and swelling, painful urination, itching, redness

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Molecule Description

Cefuroxime+Clavulanic Acid is used to treat various bacterial infections like infections of the urinary tract, respiratory tract and sexually transmitted diseases. It is a combined antibiotic containing cefuroxime axetil and clavulanic acid. Cefuroxime is a cephalosporin antibiotic that acts by inhibiting the cell wall synthesis of bacteria. Clavulanic acid acts by inhibiting the enzyme made by bacteria; this will help cefuroxime to function optimally. You should not use Cefuroxime+Clavulanic Acid if you are allergic to penicillins or any other ingredient of this medicine. If there is no improvement in your condition or any side effects bother you, then consult with your doctor. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting Cefuroxime+Clavulanic Acid.

Uses

Cefuroxime+Clavulanic Acid is used to treat various types of bacterial infections such as infection of the urinary tract, Lower respiratory tract, and Sexually transmitted diseases like gonorrhoea.

Contraindications

When should one not use Cefuroxime+Clavulanic Acid

As Cefuroxime+Clavulanic Acid contains cefuroxime axetil and clavulanic acid, any condition which is contraindicated with any of these when taken alone should be considered contraindicated for this combination.
If you are allergic to this medicine or any of its ingredients.
If you have a history of a severe allergy to any other antibiotics like penicillins.

Side effects

Common side effects of this drug are:

Diarrhoea
Nausea
Vomiting
Stomach pain
Flatulence (gas)
Indigestion
Headache
Itching and swelling in the vagina, painful urination
Itching, redness

Precautions and Warnings

Pregnancy

It is advised to take Cefuroxime+Clavulanic Acid only if your doctor considers it essential.

Breast Feeding

Cefuroxime+Clavulanic Acid passes into the breastmilk in small quantities. It is advised not to breastfeed during the treatment. Doctors may also recommend monitoring the baby if any fungal infection of mouth or diarrhoea develops.

Driving

It is advised not to drive or use machines when you have taken this medicine as it may cause dizziness.

Alcohol

Try to avoid alcohol intake during the treatment, as it can make you more dizzy or drowsy.

Other General Warnings

Talk to your doctor if

You have a history of an allergy to any antibiotic like cephalosporins, penicillins
You are already taking water pills, as it can affect kidney functions
You have a history of pain and swelling in the inner lining of the intestine

Mode of Action

How Does It Work?

Cefuroxime acts by inhibiting the cell wall synthesis of bacteria, which is responsible for bacterial infection. However, bacteria make an enzyme (beta-lactamases), which can destroy cefuroxime. Clavulanic acid inactivates this enzyme and hence helps cefuroxime to function optimally.

Interactions

Interactions with other medicines

Cefuroxime+Clavulanic Acid may interact with other medicines and produce an altered response. Please tell your doctor if you are using any other medicines, over-the-counter medicines (that you buy without a prescription), and herbal preparations.
There is limited information available on the interaction of this combination with other medicines. However, any interactions seen with these two components when taken alone may occur with this combination.
Oral contraceptives, antacids and medicines used in the treatment of gout, such as Probenecid, should be used cautiously.

Interactions with food items

It is recommended to take Cefuroxime+Clavulanic Acid with food to minimize gastrointestinal discomfort and enhance absorption.

Dosage

Overdose

Overdose may cause serious effects such as fits (seizures). If you think you have taken an excessive dose of Cefuroxime+Clavulanic Acid, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

It is advised not to miss any dose of antibiotics as it can fail therapy.
If you missed any dose of Cefuroxime+Clavulanic Acid, take it as soon as you remember.
If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule.
Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Yes, diarrhoea is a common side effect during the treatment but contact your doctor immediately if you have diarrhoea with blood and mucus along with stomach pain and fever. It can be a sign of inflammation of the large intestine.

You are supposed to complete the dosage prescribed by your physician. If you skip the dose or do not complete the course, it may cause resistance and decrease the effectiveness of immediate treatment.

Yes, Cefuroxime+Clavulanic Acid is safe to use under medical supervision, however in some patients, it may show allergic reactions. Inform your doctor about all other medicines and herbal preparations you are taking.

Yes, Cefuroxime+Clavulanic Acid is a combination antibiotic (a cephalosporin antibiotic with clavulanic acid), used to kill and stop the growth and spread of infection-causing bacteria in the body.

The doctor will decide the dose and duration depending on the type and severity of the underlying infection. Do not self-medicate with antibiotics in any case.

Cefuroxime+Clavulanic Acid can start showing its effect approximately after 1 hour of its consumption. However, it varies among individuals and can also vary due to the severity of the infection. As it is an antibiotic medicine, the complete effect towards the infection could be seen only after completing the full course of antibiotic treatment.

Cefuroxime+Clavulanic Acid should not be taken for COVID-19. It is advised to avoid taking any medicine to treat or prevent COVID-19 without consulting a doctor. If you have been tested positive with COVID-19, immediately inform your doctor. The doctor will prescribe you the appropriate medicine based on the severity of the underlying condition and medical history.

Cefuroxime+Clavulanic Acid contains cefuroxime axetil and clavulanic acid.

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