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Cefpodoxime+Clavulanic Acid

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Molecule Summary

Uses
Bacterial infections
Therapy
Antibiotic
Side Effects
Diarrhoea, nausea, vomiting, stomach pain
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Molecule Description

Cefpodoxime+Clavulanic Acid is an antibiotic used to treat bacterial infections in various parts of the body, including the throat, lungs, ears, urinary tract, and skin. This medication combines cefpodoxime, which inhibits bacterial growth, and clavulanic acid, which enhances the effectiveness of cefpodoxime. Take Cefpodoxime+Clavulanic Acid exactly as prescribed by your doctor. Continue taking the full course of medication even if you feel better, as stopping early may lead to treatment failure and the infection returning. Common side effects of Cefpodoxime+Clavulanic Acid are diarrhoea, nausea, vomiting and gas. If you feel the side effects persist or the condition worsens, you should contact your doctor immediately. Before using Cefpodoxime+Clavulanic Acid, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.

Uses

Cefpodoxime+Clavulanic Acid is used to treat various bacterial infections such as urinary tract, lungs, throat, skin, ear, airways and reproductive tract.

Contraindications

When should one not use Cefpodoxime+Clavulanic Acid

  • If you have an allergy to Cefpodoxime, Clavulanic acid or any of the ingredients of Cefpodoxime+Clavulanic Acid.
  • If you are allergic to the cephalosporin class of antibiotics.
  • If you have an infection that is caused by the bacteria Clostridium difficile.

Side effects

Common side effects of this drug are:

  • Diarrhoea
  • Vomiting
  • Nausea
  • Stomach pain
  • Loss of appetite
  • Headache
  • Skin rash

Precautions and Warnings

Pregnancy

Pregnancy

There is limited information about the effect of Cefpodoxime+Clavulanic Acid during pregnancy. Thus, it is recommended to take this medicine only, if it is prescribed by your doctor. Talk to your doctor if you are pregnant, think you may be pregnant or you are planning to have a baby.

Breast Feeding

Breast Feeding

Cefpodoxime+Clavulanic Acid passes into the breast milk and can cause fungal infection of the mouth and diarrhoea in your baby. Thus, it is recommended to be cautious while on this medicine. Inform your doctor if you are a nursing mother.

Driving

Driving

If you feel dizzy after taking Cefpodoxime+Clavulanic Acid, then avoid driving.

Alcohol

Alcohol

Do not take alcohol when taking Cefpodoxime+Clavulanic Acid as it can cause facial flushing, nausea, vomiting or a more severe reaction.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have a history of allergic reactions to any antibiotic.
  • You are suffering from persistent diarrhoea when on this medicine or even after discontinuing this medicine.
  • You are an alcoholic.
  • You have liver or kidney problems.
  • You are suffering from fits.

Mode of Action

How Does It Work?

  • Cefpodoxime controls the growth of bacteria and kills them by inhibiting the synthesis of the bacterial cell wall. However, the bacteria make an enzyme (beta-lactamases) that can destroy Cefpodoxime.
  • Clavulanic acid inactivates this enzyme and hence helps Cefpodoxime to function optimally.

Interactions

Interactions with other medicines

  • Concomitant use of acid-lowering medicines like antacids, ranitidine, and cimetidine with Cefpodoxime+Clavulanic Acid decreases the effect of this medicine.
  • Concomitant use of Probenecid with Cefpodoxime+Clavulanic Acid increases the effect of this medicine.
  • When medicines known to cause harm to the kidney such as amphotericin-B, vancomycin, and amikacin are administered along with Cefpodoxime+Clavulanic Acid, they may increase the risk of kidney disease.
  • Discuss with your doctor about any other medicines, herbal preparations and supplements you are taking currently to avoid any possible interactions.

Interactions with food items

Cefpodoxime+Clavulanic Acid can be taken with or without food. However, some sources recommend taking it with food to avoid stomach discomfort.

Dosage

Overdose

Symptoms of an overdose include nausea, vomiting and diarrhoea. If you think you have taken too much of Cefpodoxime+Clavulanic Acid, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

It is advisable not to miss any dose of antibiotics as it can result in the failure of therapy. If you have missed any dose of Cefpodoxime+Clavulanic Acid, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of this medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

You need to complete the full course of Cefpodoxime+Clavulanic Acid, as per your doctor's prescribed duration. If you stop it early, there may be chances of the reoccurrence of infection.

Flu is generally caused by viruses. This medicine only works against bacteria and not viruses. Do not self-medicate with antibiotics. Seek medical help and follow your doctor's advice.

Yes, Cefpodoxime+Clavulanic Acid is an antibiotic used to treat various bacterial infections.

Yes, Cefpodoxime+Clavulanic Acid can be used to treat an ear infection caused mainly by a bacterial organism. Your doctor may prescribe the appropriate one depending on your condition and severity.

Yes, taking Cefpodoxime+Clavulanic Acid may cause diarrhoea, as a common side effect. It is advised to keep yourself hydrated to replace the lost fluids.

No, Cefpodoxime+Clavulanic Acid is an antibiotic and antibiotics have to be taken for the complete course as prescribed by your doctor. To ensure complete and effective treatment, take medicine for the full course, even if you start feeling fine midway.

Yes, Cefpodoxime+Clavulanic Acid can be used to treat throat infection caused by various susceptible bacterial organisms. Your doctor might prescribe you the one based on causative organisms and their sensitivity to this medicine.

Cefpodoxime+Clavulanic Acid can be taken with or without food, as advised by the doctor. However, if you feel stomach discomfort then you can take it with food. But it is advisable to take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time will reduce the chances of missing the dose and it will also help you to get optimum results.

Cefpodoxime+Clavulanic Acid can start showing its effect approximately after 1 hour of its consumption. However, it varies among individuals and can also vary due to the severity of the infection. As it is an antibiotic medicine, the complete effect towards the infection could be seen only after completing the full course of antibiotic treatment.

A fever could be due to different causes. You should not self-medicate Cefpodoxime+Clavulanic Acid or any other antibiotic medicine for fever. The doctor will prescribe you the appropriate medicine after proper diagnosis. Hence it would be best to take a doctor's advice before taking any medicine to treat fever. Refrain from self-medication.

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