Cefixime+Potassium Clavulanate(Clavulanic Acid)

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Molecule Description

Cefixime+Potassium Clavulanate / Clavulanic acid is a combination medicine. It is used to treat a wide range of bacterial infections including infection of the urinary tract, ear, lungs, throat, tonsil and skin. It is also used for the treatment of gonorrhoea (a sexually transmitted disease) and enteric (typhoid) fever. Both, Cefixime & Potassium Clavulanate (also called Clavulanic acid) work by inhibiting the formation of the cell wall and killing the various susceptible bacterial organisms. Cefixime+Potassium Clavulanate / Clavulanic acid is available in the form of a tablet, dry syrup, suspension. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.

Uses

Cefixime+Potassium Clavulanate / Clavulanic acid is used to treat severe bacterial infections of the urinary tract, ear, lungs, throat, tonsil and skin or infections like typhoid fever or gonorrhoea.

Contraindications

When should one not use Cefixime+Potassium Clavulanate(Clavulanic Acid)

If you are allergic to cefixime, clavulanic acid or similar medicines like cephalosporin class of antibiotics.

Side effects

Common side effects of this drug are:

Nausea
Vomiting
Stomach pain
Indigestion
Diarrhoea

Precautions and Warnings

Pregnancy

Consult your doctor before using cefixime+potassium clavulanate / clavulanic acid as there is limited information about its safety during pregnancy. Your doctor will only prescribe you this medicine if considered essential after assessing the benefits over risks.

Breast Feeding

Consult your doctor before taking cefixime+potassium clavulanate / clavulanic acid while breastfeeding as limited information is available about its safety in lactating mothers.

Driving

Cefixime+Potassium Clavulanate / Clavulanic acid may cause sleepiness, thus you need to be cautious while driving.

Alcohol

Avoid consuming alcohol with cefixime+potassium clavulanate / clavulanic acid, as it may worsen the side effects.

Other General Warnings

Talk to your doctor if

You are suffering from kidney or liver problems.
You have a history of an allergy to penicillins, cephalosporins
You have a blood clotting problem or you are taking any anticoagulant medicine
You experience persistent diarrhoea
You have a history of infection and swelling in the colon (colitis)
You have a history of haemolytic anaemia (decreased red blood cells)
Inform the doctor, or the laboratory person know that you are using this medicine while going for a lab test, as this medicine may interfere with certain lab tests.

Mode of Action

How Does It Work?

Cefixime controls the growth of bacteria and kills them by inhibiting the synthesis of the bacterial cell wall. However, the bacteria can make an enzyme (beta-lactamases) that can destroy cefixime.
Potassium Clavulanate (also called Clavulanic acid) inactivates this enzyme. This helps cefixime to function optimally.

Interactions

Interactions with other medicines

Some medicines can affect the way Cefixime+Potassium Clavulanate / Clavulanic acid works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction. Also, you should inform your doctor if you have a planned surgery or vaccination scheduled.
This combination can increase the levels of carbamazepine (a medicine used for controlling fits or nerve pain), thus monitoring is required.
If you are taking blood thinners like warfarin, there may be an increased risk of bleeding.
If you are taking birth control pills like oral contraceptives (O.C pills), caution is needed as this medicine interferes with their action.
If you are undergoing a glucose test (to detect the amount of glucose in the blood), a false 'positive reaction' may occur.
If you are undergoing a coombs test (to detect antibodies attached to red blood cells), a false 'positive reaction' may occur.

Frequently Asked Questions (FAQs)

Cefixime+Potassium Clavulanate / Clavulanic acid is an antibiotic and is used in treating severe infections of the urinary tract, lungs, throat, tonsil and skin caused by bacteria.

Cefixime+Potassium Clavulanate / Clavulanic acid is available in the form of tablet, dry syrup, suspension.