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Cefixime+Dicloxacillin

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Molecule Summary

Uses
Bacterial Infection
Therapy
Antibiotic
Side Effects
Nausea, vomiting, headache, dizziness
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Molecule Description

Cefixime+Dicloxacillin is a medicine used to treat various bacterial infections, including those affecting the throat, ears, sinuses, lungs, urinary tract, skin, and soft tissues. It can also be used for dental and post-surgical infections. This combination helps cover a wide range of bacteria, making it useful when the exact cause of the infection is unknown. The two active ingredients, cefixime and dicloxacillin, work by killing bacteria. They block the bacteria's ability to form a protective outer wall, which is essential for their survival. Once the wall is damaged, the bacteria break apart and die, allowing your body to recover from the infection. This medicine should not be taken if you are allergic to cephalosporins, penicillins, or similar antibiotics. It can cause side effects like nausea, diarrhoea, headache, dizziness, indigestion, or a bad taste in the mouth. If any symptoms persist or become severe, consult your doctor. Some medicines can interact with Cefixime+Dicloxacillin, including those that affect your immune system, gout medications like allopurinol or probenecid, and even oral contraceptives, whose effectiveness may be reduced. Always inform your doctor about all medicines and supplements you're taking before starting this treatment. Avoid alcohol while taking this medicine, as it can increase stomach-related side effects. If you are pregnant, breastfeeding, or have kidney, liver, or stomach issues, talk to your doctor first. Also, be careful when driving, as the medicine may cause dizziness or nausea. Always take the prescribed dose and do not double it if a dose is missed.

Uses

Cefixime+Dicloxacillin is used in the treatment of bacterial infections.

Contraindications

When should one not use Cefixime+Dicloxacillin

  • If you are allergic to cefixime, dicloxacillin or any other ingredients of Cefixime+Dicloxacillin.
  • If you are allergic to cephalosporins (a type of antibiotic), penicillins or imipenem.

Side effects

Common side effects of this drug are:

  • Nausea, Vomiting
  • Headache, Dizziness
  • Diarrhoea
  • Indigestion, gases, bloating
  • Stomach ache
  • Bad taste in the mouth

Precautions and Warnings

Pregnancy

Pregnancy

There is limited data available about the safety of this medicine in pregnant women. It is advisable that you consult your doctor before using this medicine.

Breast Feeding

Breast Feeding

The active ingredients of this medicine are known to pass through the mother's milk to the baby and cause unwanted, harmful effects on the newborn. Thus, it is not recommended to use this medicine if you are breastfeeding your baby.

Driving

Driving

You may feel nauseous and dizzy after taking this medicine, which may interfere with your ability to drive. Thus, if you are experiencing any such symptoms or feeling uneasy, it is recommended that you should not drive and take a rest.

Alcohol

Alcohol

This medicine can cause nausea, vomiting, and stomach ache, which can be further worsened by alcohol. Thus, it is advised not to consume alcohol while taking this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are pregnant or planning to become pregnant.
  • You are a breastfeeding mother.
  • You have taken a vaccine against any bacterial infection.
  • You are taking oral contraceptive pills, as this medicine may reduce the efficacy of the contraceptive pills. It is suggested that you should use physical contraceptive methods when taking this medication.
  • You have a kidney disorder, as prolonged use of this medicine may damage the kidneys all the more.
  • You are suffering from a kidney, liver disorder, or any illness related to the stomach that may cause nausea, vomiting and digestive problems.
  • You have a weak immune system or are taking medicines that affect the immune system.
  • You are suffering from anaemia.
  • You are suffering from colitis (a condition of inflammation of the colon).
  • You are suffering from diarrhoea.

Mode of Action

How Does It Work?

  • Cefixime works by stopping the growth of bacteria that cause infections. It does this by interfering with the bacteria's ability to form a protective outer wall, which is essential for their survival. Without this wall, the bacteria break apart and die, helping your body clear the infection more effectively.
  • Dicloxacillin helps treat infections by killing the bacteria causing them. It works by blocking the bacteria's ability to make a protective cell wall, which they need to live. Without this wall, the bacteria become weak and break apart, allowing your body to eliminate the infection.

Interactions

Interactions with other medicines

  • Concomitant use of Cefixime+Dicloxacillin along with medicines that alter or weaken your immune system, like prednisone, dexamethasone, methylprednisolone, methotrexate, should be avoided.
  • Concomitant use of this medicine along with oral contraceptive pills should be avoided as the active ingredients in this medicine reduce the effect of oral contraceptive pills.
  • When used together with a medicine used to treat kidney stones and gout (allopurinol), the risk of allergic skin reaction increases.
  • Medicines like probenecid, used to treat gout and high uric acid levels, may cause a delay in the secretion of dicloxacillin from the body, leading to unwanted effects.
  • Caution should be exercised while using medicines like warfarin along with Cefixime+Dicloxacillin as cefixime tends to increase the prothrombin time (delays blood clotting).
  • Discuss with your doctor any other medicine, herbal preparation, and supplements you are taking currently to avoid any possible drug interactions.

Dosage

Overdose

  • Taking more than the recommended dosage of this medicine may cause severe nausea, vomiting and diarrhoea, which can be severe. An overdose may be harmful to those who are suffering from kidney disease.
  • If you experience fits, mental confusion, difficulty in making movements, loss of alertness you should visit your doctor or nearest hospital as it may be early warning signs of encephalopathy a disease of the brain.
  • If you have taken too much of this medicine, then contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you missed a dose of the medicine, take it as soon as you remember. If it is time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

Frequently Asked Questions (FAQs)

This medicine can be used to treat bacterial infections, whereas the common cold is primarily caused by a viral infection; therefore, this medication would not be effective against the common cold. However, consult the doctor before use and avoid self-medication.

Cefixime+Dicloxacillin is intended for use against bacterial infections and is not known to affect blood pressure or interact with those medicines. It is nevertheless recommended that you should inform your doctor about your high blood pressure and medications you take for the same before taking this medicine.

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