Budesonide+Formoterol

Uses	Asthma and COPD
Therapy	Anti-Asthmatic, Drugs For Chronic Obstructive Pulmonary Disease
Side Effects	Headache, nausea, vomiting, stomach discomfort, dizziness

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Molecule Description

Budesonide+Formoterol is a combination medicine containing formoterol and budesonide. It is used to relieve symptoms of asthma and COPD like wheezing, shortness of breath, chest tightness, etc. It should be used as prescribed and not discontinued unless advised by your doctor, as a sudden stoppage can cause the disease to worsen. Headache, nausea, vomiting, cough, irritation in the throat and palpitations are a few side effects that you may experience after taking this medicine. Consult your doctor if you observe any white patches in your mouth or experience any discomfort or new symptoms on the consumption of the medicine. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting Budesonide+Formoterol.

Uses

Budesonide+Formoterol is used in patients with asthma and chronic obstructive pulmonary disease (COPD) to relieve symptoms such as coughing, wheezing, breathing difficulty, chest tightness.

Contraindications

When should one not use Budesonide+Formoterol

If you are known to be allergic to any components or excipients of Budesonide+Formoterol.
If you are suffering from acute breathlessness as seen in a severe attack of asthma or COPD or cases of a collapsed airway.

Side effects

Common side effects of this drug are:

Headache, dizziness
Nausea, vomiting
Stomach discomfort
Body pain
Coughing, sore throat
Hoarseness of voice
Respiratory tract infections
Fungal infection in the mouth
Palpitations

Precautions and Warnings

Pregnancy

There is limited information about the effects of this medicine on human pregnancy. You will be prescribed this medicine by your doctor only if it is essential and benefits over-weighs risks.

Breast Feeding

As this medicine passes into breast milk, you should consult your doctor before using this while breastfeeding.

Driving

This medicine may make you dizzy, avoid driving if you do not feel well or are unable to be alert.

Alcohol

It is recommended to avoid consuming alcohol while on treatment with this medicine, as it may worsen your condition.

Other General Warnings

Talk to your doctor if

You have severe liver problems.
You have diabetes or a lung infection.
You have problems with your heart like high blood pressure, heart failure, etc.
Your asthma condition is suddenly worsening.
You have an overactive thyroid gland.
You have a low blood potassium level.
You feel that the treatment is ineffective.
You are on any medicines that suppress immunity; there is an increased chance of developing infections. Necessary vaccinations and care should be taken to avoid this.
Orally inhaled steroidal medicines may cause growth retardation in children. Hence, growth monitoring is recommended.
Keep taking this medicine as prescribed, even if your symptoms go away. Your doctor will reduce your dose when required.
Abruptly stopping the medicine can be dangerous and should be strictly avoided.

Mode of Action

How Does It Work?

Budesonide+Formoterol works by the combined action of Formoterol and Budesonide.
Budesonide is a corticosteroid medicine, which on inhalation reduces inflammation in the airways in a dose-dependent manner, thus reduces the chances of worsening asthma.
Formoterol acts on the muscles in the airway tract. In the presence of inflammation (like in asthma), these muscles lead to constriction of the airway and cause breathlessness.
Formoterol relaxes these muscles, facilitating the opening of the airway and thus relieving breathlessness.

Interactions

Interactions with other medicines

Concomitant use of Budesonide+Formoterol along with medicines such as Ketoconazole (anti-fungal medicine), Ritonavir (used in HIV infection) and Clarithromycin (antibiotic) should be avoided as it may alter the effects of this medicine.
Effects of this medicine can be weakened by some medicines used to control blood pressure or treat heart-related illnesses like Propranolol, Atenolol and others belonging to the same class.
Concomitant treatment with Quinidine, Disopyramide, Procainamide, Phenothiazines, Antihistamines (like Terfenadine), medicines used in psychiatric illness like Isocarboxazid, Doxepin can lead to increased chances of developing disorders related to the heart rhythm.
You may be at an increased risk of experiencing cardiac side effects when taking L-Dopa (used in Parkinson's diseases), L-thyroxine (thyroid hormone) along with this medicine.
Medicines like Procarbazine (anti-cancer) can lead to a rise in blood pressure if used simultaneously with this medicine. It is important to inform your anaesthetist about your asthma medications to avoid interactions of this medicine with some anaesthetic agents (like Diazepam, Amobarbital).
Low potassium levels caused due to this medicine may lead to increased chances of heart disorders if you are taking Digitalis (used for heart failure). Also, water-pills except the potassium-sparing ones lead to lowering of potassium in body and caution is advised if you are taking these along with this medicine.

Dosage

Overdose

The symptoms of overdose are headache, nausea, vomiting, palpitations, increased heartbeats, increased blood glucose, low potassium levels, and change in the heart's rhythm. Consult your doctor if you experience any symptoms or think may have taken too much of this medicine.

Missed a Dose

If you miss any dose of this medicine, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of this medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

This medicine contains two medicines - Formoterol and Budesonide of which, Budesonide is a steroid.

There is limited information about the safety of Budesonide+Formoterol during pregnancy. However, your doctor may give you this medicine only if it is needed and the advantage over-weighs the risk. You should always consult a doctor before taking any medication during pregnancy.

You should use Budesonide+Formoterol for as long as your doctor recommends. The doctor will decide how often you need to use your inhaler on the basis of an underlying condition.

It is usually prescribed for a long duration. It will show its full effect in a few weeks after using this inhaler.