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Bisoprolol+Hydrochlorothiazide

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Molecule Summary

Uses
High blood pressure
Therapy
Anti-Hypertensive
Side Effects
Headache, dizziness, sleepiness, nausea, diarrhoea, fatigue
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Molecule Description

Bisoprolol+Hydrochlorothiazide is an anti-hypertensive medicine. It contains a combination of two medicines - Bisoprolol and Hydrochlorothiazide. It is used to treat mild to moderate high blood pressure. While taking this medicine you should be cautious of your diet and should also exercise regularly. It should be taken as directed by the doctor and in doses and duration as prescribed. It can be taken with or without food. Do not miss any dose or take it more than that recommended by the doctor. Before starting Bisoprolol+Hydrochlorothiazide, it is mandatory to inform your doctor about your past medical history and the medicines you take. Also, inform the doctor if you are pregnant, planning a pregnancy or are breastfeeding.

Uses

Bisoprolol+Hydrochlorothiazide is used for the treatment of mild to moderate hypertension (high blood pressure).

Contraindications

When should one not use Bisoprolol+Hydrochlorothiazide

  • If you are allergic to bisoprolol, hydrochlorothiazide or any other ingredients of Bisoprolol+Hydrochlorothiazide.
  • If you have anuria (non-passage of urine).
  • If you are suffering from heart problems like heart failure, shock, sinus bradycardia, etc.

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Indigestion
  • Cough
  • Sleepiness
  • Fatigue
  • Lack of sleep
  • Chest pain

Precautions and Warnings

Pregnancy

Pregnancy

Bisoprolol+Hydrochlorothiazide should not be used during pregnancy as there is limited safety data available in pregnant women, thus you should consult your doctor. Your doctor will only prescribe you this medicine if considered essential after assessing the benefits over risks.

Breast Feeding

Breast Feeding

Bisoprolol+Hydrochlorothiazide is not recommended for use while breastfeeding as it is unknown if its components pass into the breastmilk. Your doctor may suggest an alternative medicine especially when you are breastfeeding a newborn or premature baby.

Driving

Driving

Bisoprolol+Hydrochlorothiazide may make you feel dizzy and sleepy, thus you should avoid driving if you do not feel well or are unable to be alert.

Alcohol

Alcohol

It is unsafe for you to consume alcohol while on treatment with Bisoprolol+Hydrochlorothiazide as it may worsen your condition.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have any pre-existing health conditions such as heart diseases, liver or kidney problems, thyroid disorder, asthma or respiratory problem, diabetes, etc.
  • You are going to have major surgery or any lab test, as this medicine may alter the results.
  • You have glaucoma.
  • You are a smoker.
  • Your blood volume and electrolyte levels may be altered while on treatment with this medicine causing symptoms like nausea, muscle weakness, fatigue, low blood pressure, fast heart rates. If you experience any of these symptoms contact your doctor immediately.
  • Bisoprolol+Hydrochlorothiazide is not recommended for use in patients less than 18 years of age.
  • Do not discontinue the treatment suddenly without consulting your doctor, as it may worsen your condition.

Mode of Action

How Does It Work?

  • Bisoprolol+Hydrochlorothiazide works by the combined action of its main components – Bisoprolol and Hydrochlorothiazide.
  • Bisoprolol works by blocking certain chemicals in the body that affect the heart and blood vessels, thus reducing the heart rate and makes it easier for your heart to pump blood around your body.
  • Hydrochlorothiazide works by helping the body get rid of extra fluid or water through urine thus eventually lowering your blood pressure.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Bisoprolol+Hydrochlorothiazide works or this medicine itself can reduce the effectiveness of other medicines taken at the same time. Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • In particular, tell your doctor if you are taking medicines such as painkillers, heart-related medicines, other anti-hypertensive medicines, blood thinners, anti-diabetic medicines like insulin, antacids, etc.

Interactions with food items

Bisoprolol+Hydrochlorothiazide can be taken with or without food.

Dosage

Overdose

Excess of Bisoprolol+Hydrochlorothiazide may lead to irregular heartbeats, low blood pressure and fits. Symptoms of an overdose include dizziness, nausea, vomiting, sleepiness, weakness, confusion, muscle cramps, dehydration, fatigue, unconsciousness. Seek urgent medical help if you experience any symptoms or feel you have taken too much of this medicine.

Missed a Dose

In case you've missed taking any dose of Bisoprolol+Hydrochlorothiazide, take it as soon as you remember it. If it is almost time for the next dose, then skip the missed dose. Avoid taking a double dose to compensate for the missed dose.

Frequently Asked Questions (FAQs)

You have to take Bisoprolol+Hydrochlorothiazide as directed by your doctor. It can be taken either with or without food.

You should plan a balanced diet that has proteins, whole grain fibrous fruits and vegetables. Please consult your doctor before starting any diet or food habits. You need to limit carbohydrate, salt and sugar intake. Also exercise regularly and reduce weight. You must avoid smoking or drinking.

No, do not stop taking Bisoprolol+Hydrochlorothiazide suddenly, as it could worsen your condition of high blood pressure. Instead, you should consult your doctor and he/she may adjust your dose.

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