Azithromycin+Cefixime

When should one not use Azithromycin+Cefixime

• If you are allergic to azithromycin, cefixime, or any other ingredient of Azithromycin+Cefixime.
• If you are allergic to erythromycin, any macrolide or ketolide antibiotic, or cephalosporin antibiotics. If you are not sure what these medicines are, please confirm with your doctor.

Common side effects of this drug are:

• Diarrhoea
• Nausea
• Vomiting
• Abdominal pain
• Flatulence (gas)

Other General Warnings

• You have liver, kidney, or heart problems.
• Your blood levels of potassium or magnesium are too low.
• You develop signs of another infection.
• You are taking any ergot derivatives such as ergotamine (to treat migraine).
• You have a certain type of muscle weakness called myasthenia gravis.
• You have ever had colitis.
• You feel your heart beating in your chest or have an abnormal heartbeat, or get dizzy or faint or
• suffer from any muscle weakness.
• You develop diarrhoea or loose stools during or after treatment.
• You develop severe skin reactions after using this medicine.

How Does It Work?

• Azithromycin+Cefixime contains a combination of azithromycin and cefixime as active substances.
• Azithromycin prevents the protein synthesis in the bacteria which kills or inhibits the growth of infection-causing bacteria.
• Cefixime binds to certain proteins called penicillin-binding proteins (PBPs) in the bacteria. This prevents the formation of the bacterial cell wall and causes the death of infection-causing bacteria.

Interactions with other medicines

• Some medicines can affect the way Azithromycin+Cefixime works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Inform your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• Particular care should be taken if you are taking medicines called antacids - used for heartburn and indigestion, warfarin or similar medicines - used to thin the blood, zidovudine or nelfinavir - used to treat HIV infections, rifabutin - used to treat tuberculosis, quinidine - used to treat heart rhythm problems, ciclosporin - used to stop your body rejecting an organ transplant.
• Ergotamine - used for migraine, should not be taken at the same time as Azithromycin+Cefixime.
• Terfenadine - used to treat hay fever or skin allergy and hydroxychloroquine or chloroquine - used to treat conditions including rheumatoid arthritis, or to treat or prevent malaria, should not be taken at the same time as this medicine as it may cause severe heart problems.
• Azithromycin+Cefixime can make the effects of medicines like digoxin - used to treat heart failure and colchicine - used for gout and familial Mediterranean fever stronger.

Overdose

Missed a Dose