Clindamycin+Adapalene
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Molecule Description
Adapalene+Clindamycin is a combination medicine. It is used to treat acne. Both the medicines work by inhibiting the growth of bacteria causing pimples, reducing swelling and inhibiting the formation of blemishes due to the accumulation of oil and dirt. Clindamycin belongs to a class of medications known as antibiotics and adapalene is derived from vitamin A. Adapalene+Clindamycin is available in the form of cream, ointment, gel, nanogel, soap.
Uses
Adapalene+Clindamycin is used for the treatment & management of acne.
Contraindications
When should one not use Clindamycin+Adapalene
- If you are allergic to clindamycin, adapalene or similar medicines
- If you have ever developed diarrhoea on the use of an antibiotic medicine
- If you have a history of inflammatory bowel disease
Side effects
Common side effects of this drug are:
Application site reactions
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You experience skin reactions.
- You have a history of inflammation of the colon or antibiotic-associated diarrhoea.
- You should not use this medicine if you are prone to allergies.
- Avoid unnecessary exposure to sunlight after using this medicine.
Mode of Action
How Does It Work?
- Clindamycin works by inhibiting the protein synthesis in the bacteria responsible for causing infection and thus inhibits the growth of infection-causing bacteria.
- Adapalene works by inhibiting the rooting of pimples inside the skin and decreasing swelling and inflammation. It also removes dead skin cells and enhances the deeper penetration of clindamycin.
Interactions
Interactions with other medicines
- Some medicines can affect the way adapalene+clindamycin works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, herbals you are currently taking or are using other topically applied medicines like cream, lotion and gel to avoid any possible interaction.
- Adapalene+Clindamycin should be used with caution along with blood-thinning medicines.
Dosage
Overdose
Seek urgent medical help if you suspect an overdose.
Missed a Dose
If you have missed using adapalene+clindamycin, use it as soon as possible. Do not overuse it just to compensate for the missed dose.
Frequently Asked Questions (FAQs)
Articles
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References:
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 27 Oct 2025]
- Acnetor AD [Internet]. Torrentpharma.com. 2025 [cited 27 Oct 2025]
- Dalacin - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 27 Oct 2025]
- Differin - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 27 Oct 2025]
- Improvement in atrophic acne scars by topical adapalene [Internet]. Jaad.org. 2025 [cited 27 Oct 2025]
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