Aceclofenac+Paracetamol / Acetaminophen+Trypsin Chymotrypsin

Uses	Joint pain, swelling, muscle ache
Therapy	Analgesic/Antipyretic, Anti-Inflammatory
Side Effects	Rashes, ulcer, stomach discomfort

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Molecule Description

Aceclofenac+Paracetamol / Acetaminophen+Trypsin Chymotrypsin is used for relieving swelling and pain in joints and bones. It consists of three ingredients trypsin-chymotrypsin along with paracetamol and aceclofenac. Trypsin and chymotrypsin are enzymes that improve healing and stimulate tissue repair. Paracetamol and Aceclofenac produce action by blocking the enzyme responsible for producing prostaglandins which cause inflammation and swelling.

Uses

Aceclofenac+Paracetamol / Acetaminophen+Trypsin Chymotrypsin is used for the management of pain, swelling and inflammation of joints and bones, different types of arthritis and other bone-related disorders.

Contraindications

When should one not use Aceclofenac+Paracetamol / Acetaminophen+Trypsin Chymotrypsin

If you are allergic to any of the ingredients of this medicine.
Individuals having a history of liver or kidney problem or dysfunction.
Patients with active or history of stomach ulcers or bleeding in the digestive tract.
Patients with a history of the heart-related disease, high blood pressure or bleeding disease.
Hypersensitive reactions like asthma, rashes noticed with other painkillers.

Side effects

Common side effects of this drug are:

Skin rashes
Mouth ulcers
Bleeding
Difficulty in breathing
Black stools
Nausea
Weight loss
Appetite loss
Kidney failure
Fever
Head pain

Precautions and Warnings

Pregnancy

The medicine should be avoided in pregnancy as the safety of this combination is not established in pregnant women.

Breast Feeding

Components of the medicine may pass into breast milk. Hence, it should be avoided during breastfeeding.

Driving

Possible side effects of the medicine include dizziness, the spinning of the head, drowsiness, and visual disturbances. If affected please do not drive.

Alcohol

Alcohol is not known to interact with medicine. However, it is advised to consult the doctor if you drink too often.

Other General Warnings

Talk to your doctor if

You experience skin rashes, allergy, swelling of lips, and face after taking the medicine.
You may have severe liver, kidney or heart disorder such as high blood pressure, heart failure, etc.
You may have issues related to clotting of blood or related disorders.
You are an elderly patient, thus the chances of getting side effects are more.
You experience fluid retention and bloating after taking the medicine.
You may have Crohn's disease, characterised by severe diarrhoea, weakness, and weight loss.
You have undergone surgery on part of the digestive system.
You have a condition called Systemic Lupus Erythematosus (SLE) characterised by joint pains, rashes, and fever.
You may experience severe allergic skin disorders characterised by redness and scales on the skin or painful rash and blisters (Stevens-Johnson syndrome).
You have other infections such as chickenpox.
You should not take other medicine containing paracetamol with Aceclofenac+Paracetamol / Acetaminophen+Trypsin Chymotrypsin.

Mode of Action

How Does It Work?

Paracetamol and aceclofenac work by reducing the production of certain chemicals such as prostaglandins which cause inflammation, swelling, pain, and fever.
Trypsin and chymotrypsin are the enzymes that help in reducing inflammation. It may improve blood circulation and fastens the healing process.

Interactions

Interactions with other medicines

Aceclofenac+Paracetamol / Acetaminophen+Trypsin Chymotrypsin should be taken cautiously with warfarin, aspirin, and citalopram because of the risk of increased bleeding.
Aceclofenac+Paracetamol / Acetaminophen+Trypsin Chymotrypsin may reduce the activity of blood pressure-lowering medicines like Enalapril, Telmisartan, and water pills when used in combination.
When used with cyclosporine, tacrolimus and methotrexate kidney function needs to be monitored regularly.
This medicine should not be taken along with steroids as it may increase the risk of bleeding in the digestive tract.
The medicine should be avoided in patients suffering from chickenpox because of the chances of skin allergies.
Other medicines such as anti-diabetics, zidovudine, mifepristone, lithium should be used cautiously with Aceclofenac+Paracetamol / Acetaminophen+Trypsin Chymotrypsin as it may increase or decrease the action.
Tell the doctor about all other medicines and supplements you are taking while he prescribes you the medicine.

Dosage

Overdose

Symptoms of overdose of the medicine include nausea, headache, vomiting, diarrhoea, drowsiness, anorexia, and abdominal pain. If you happen to take too much of the medicine inform the doctor or reach out to the nearest hospital immediately. Since the medicine contains paracetamol as one of its ingredients, significant overdose can also impact liver function.

Missed a Dose

It is advised to take the medicine for as long as the doctor recommends. Do not take a double dose to make up for a forgotten dose. If you forget to take a dose, take it as soon as you remember it. Then, take the next dose at the right time.

Frequently Asked Questions (FAQs)

Aceclofenac+Paracetamol / Acetaminophen+Trypsin Chymotrypsin is used for the management of pain, swelling or inflammation of joints and bones, different types of arthritis and other bone-related disorders.

The medicine should be avoided during pregnancy as its safety in pregnant women is not established. You should consult the doctor before taking any medicine during pregnancy.

The medicine is advised to be taken with or after having a meal.

It contains paracetamol and aceclofenac that has painkiller action.