Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin

Uses	Joint pain, swelling, muscle ache
Therapy	Anti-Inflammatory, Analgesic/Antipyretic
Side Effects	Rashes, ulcer, stomach discomfort

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Molecule Description

Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin is used for relieving swelling and pain in joints and bones. It is a combination medicine containing trypsin-chymotrypsin, paracetamol and aceclofenac. Trypsin and Chymotrypsin are enzymes that improve healing and stimulate tissue repair. Paracetamol and Aceclofenac produce their action by blocking an enzyme responsible for producing chemical substances such as prostaglandins which cause inflammation and swelling. Take this medicine as advised by your doctor. You can take Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin with food to avoid stomach upset.

Uses

Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin is used for the management of pain, swelling and inflammation of joints and bones, different types of arthritis and other bone-related disorders.

Contraindications

When should one not use Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin

If you are allergic to trypsin-chymotrypsin, paracetamol, aceclofenac, or any of the ingredients of Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin.
If you have severe liver, kidney or heart disease or a bleeding disorder.
If you experience hypersensitive reactions like asthma and rashes noticed with other pain killers.

Side effects

Common side effects of this drug are:

Skin rashes
Mouth ulcers
Bleeding
Black stools
Nausea
Weight loss
Appetite loss
Fever

Precautions and Warnings

Pregnancy

Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin should be avoided in pregnancy as the safety of this combination is not established in pregnant women.

Breast Feeding

Components of Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin may pass into breast milk. Hence, it should be avoided during breastfeeding.

Driving

Possible side effects of Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin include dizziness, the spinning of the head, drowsiness and visual disturbances. If affected please do not drive.

Alcohol

Alcohol may increase the risk of side effects, including liver damage, with this medicine. It is advised to avoid alcohol and consult your doctor if you drink often.

Other General Warnings

Talk to your doctor if

You experience skin rashes, allergy, swelling of lips and face after taking this medicine
You have severe liver, kidney or heart disorder such as high blood pressure, heart failure, etc.
You have issues related to the clotting of blood or related disorders.
You are an elderly patient, as the chances of getting side effects are more.
You experience fluid retention and bloating after taking this medicine.
You have Crohn's disease, characterised by severe diarrhoea, weakness and weight loss.
You have undergone surgery on any part of the digestive system.
You have a condition called Systemic Lupus Erythematosus (SLE) characterised by joint pain, rashes and fever.
You experience severe allergic skin disorders characterised by redness and scales on the skin or painful rash and blisters (Stevens-Johnson syndrome).
You have any other infections such as chickenpox.
You should not take any other medicine containing paracetamol with Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin.

Mode of Action

How Does It Work?

Paracetamol and Aceclofenac work by reducing the production of certain chemicals such as prostaglandins that cause inflammation, swelling, pain and fever.
Trypsin and chymotrypsin are enzymes that help in reducing inflammation and swelling and support the healing process.

Interactions

Interactions with other medicines

Sometimes Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin may affect the way other medicines work, and other medicines may affect how Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin works if taken at the same time.
Always inform your doctor about all the medicine you are taking, that includes all prescribed or non-prescribed herbal medicines, dietary supplements as well as other treatment if you are taking for any disorder.
Take special care if you are taking medicines for hypertension, immunosuppressants etc.
Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin should be taken cautiously with anticoagulants (like warfarin), painkiller like aspirin, citalopram, steroids because of the risk of increased bleeding.
This medicine should be avoided in patients suffering from chickenpox because of the chances of skin allergies.
Other medicines such as anti-diabetics, anti-HIV (zidovudine), oral contraceptives, brain-related medicines like lithium should be used cautiously with Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin, as it may increase or decrease their action.

Dosage

Overdose

Symptoms of overdose of this medicine include nausea, headache, vomiting, diarrhoea, drowsiness, anorexia, abdominal pain. If you happen to take too much of this medicine inform your doctor or reach out to the nearest hospital immediately. Since this medicine contains paracetamol as one of its ingredients significant overdose can also impact liver function.

Missed a Dose

It is advised to continue to take the medicine for as long as the doctor recommends. Do not take a double dose to make up for a forgotten dose. If you forget to take a dose, take it as soon as you remember it. Then, take the next dose at the right time.

Frequently Asked Questions (FAQs)

Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin is used for the management of pain, swelling or inflammation of joints and bones, different types of arthritis and other bone-related disorders.

This medicine should be avoided in pregnancy as its safety has not been established. You should consult your doctor before taking any medicine during pregnancy.

The medicine is advised to be taken with or after having a meal.

Yes, Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin is a painkiller as well as anti-inflammatory medicine. It contains paracetamol and aceclofenac that has pain relieving action.

You should not take Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin if you have severe liver, kidney or heart disease or a bleeding disorder.

Skin rashes, mouth ulcers, bleeding, black stools, nausea, weight loss are a few common side effects that can be seen during the treatment. Bleeding or black stools can be serious, so seek medical help immediately if you notice them. Also, not everyone experiences the same side effects.

Aceclofenac+Paracetamol / Acetaminophen+Chymotrypsin-Trypsin may be used or advised following a tooth extraction to provide relief from tooth pain and swelling. However, self-medication should not be practised as it may lead to unwanted side effects.