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Molecule Description

Pregabalin+Nortriptyline is a combination medicine. It is used to treat neuropa

thic pain (a sensation of numbness, tingling and also feels like pins and needles). Pregabalin+Nortriptyline is available in the form of a tablet. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.


Uses of Pregabalin+Nortriptyline

Pregabalin Nt Tablet is used for the treatment of neuropathic pain.

Contraindications of Pregabalin+Nortriptyline

When should one not use Pregabalin+Nortriptyline

  • If you are allergic to nortriptyline, pregabalin or similar medicines.
  • If you have problems with your heart, liver or kidney.
  • If you suffer from any health conditions like diabetes, high blood pressure, etc.
  • If you are currently taking any anti-depressant medications.

Side effects of Pregabalin+Nortriptyline

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Constipation
  • Dry mouth
  • Stuffed nose
  • Lack of sleep
  • Aggression

Precautions and Warnings of Pregabalin+Nortriptyline



Can I take pregabalin+nortriptyline during pregnancy?
Consult your doctor before using pregabalin+nortriptyline during pregnancy as limited safety data is available in pregnant women. Use effective contraception during treatment.

Breast Feeding

Can I take pregabalin+nortriptyline while breastfeeding?
Consult your doctor before using pregabalin+nortriptyline while breastfeeding as limited study has been done on its safety.


Can I drive if I have consumed pregabalin+nortriptyline?
Avoid driving if you feel dizzy after taking pregabalin+nortriptyline.


Can I consume alcohol with pregabalin+nortriptyline?
Avoid consuming alcohol with pregabalin+nortriptyline, as it may worsen the side effects.

Other General Warnings

Talk to your doctor if
  • You experience any allergic reactions after taking pregabalin+nortriptyline.
  • You have any pre-existing medical conditions such as heart disorder, liver or kidney problem, thyroid, etc.
  • You are getting suicidal thoughts after taking this medicine, talk to your doctor immediately.
  • You have a history of fits, then never stop this medicine abruptly, your doctor shall gradually decrease the dose.
  • You are experiencing vision problems or dizziness and sleepiness.
  • Pregabalin+Nortriptyline should be used with caution in elderly patients.

Mode of Action of Pregabalin+Nortriptyline

How Does It Work?

  • Pregabalin works by reducing the release of a chemical (neurotransmitter) in the brain responsible for the sensation of pain.
  • Nortriptyline works by acting on the release of certain chemicals and electrical activity in the brain.

Interactions of Pregabalin+Nortriptyline

Interactions with other medicines

  • Some medicines can affect the way pregabalin+nortriptyline works or this medicine itself can affect the action of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially, if you are taking pain killers, steroids, blood thinners, antibiotics, muscle relaxing medicines, medicines to treat diabetes, psychiatric illnesses, fits and sleep disorders.

Content Details


Dr. Mansi Savla

B. Pharm, PharmD


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What is neuropathic pain?

A: Neuropathic pain is a condition of an abnormal painful sensation in different body parts due to damage in a part of the brain responsible for sensing external stimuli.

Q: In which all dosage forms is Pregabalin+Nortriptyline available?

A: Pregabalin+Nortriptyline is available in the form of a tablet.
Last Updated on: 20 Nov 2021 | 11:49 AM (IST)
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