Indapamide+Perindopril

Uses	High blood pressure
Therapy	Anti-Hypertensive
Side Effects	Headache, dizziness, stomach upset, visual disturbance

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Molecule Description

Indapamide+Perindopril is an anti-hypertensive medicine. It is used for the treatment of high blood pressure. Indapamide+Perindopril is a combination medicine and contains a combination of two medicines Perindopril and Indapamide. It works by removing excess fluid from the body and blocking the production of certain chemicals which tightens the blood vessels, this makes the blood flow easier.

Uses

For the treatment of high blood pressure.

Contraindications

When should one not use Indapamide+Perindopril

If you are allergic to any ingredient of this medicine or similar medicines.

Side effects

Common side effects of this drug are:

Dizziness
Fainting
Vomiting
Nausea
Upset stomach
Headache
Rashes & itching
Visual disturbance
Ringing in the ear
The spinning of the head
Fatigue
Muscle ache

Precautions and Warnings

Pregnancy

This medicine should not be used during pregnancy as it can harm the growing foetus. If pregnancy is detected while taking this medicine, immediately inform your doctor to start an alternative therapy.

Breast Feeding

Components of this medicine may pass into breast milk. It should not be used by a lactating woman.

Driving

This medicine does not affect the alertness of an individual. However, it can lead to low blood pressure in some people which is usually accompanied by fainting and dizziness. Avoid driving if you experience any of such symptoms.

Alcohol

You should not consume alcohol if you are taking blood pressure-lowering medicine. Take your doctor's advice if you have a habit of drinking regularly.

Other General Warnings

Talk to your doctor if

You have any heart, kidney or liver-related condition.
You are taking a medicine containing Lithium (used to treat mood disorders).
You have abnormally increased levels of a hormone, Aldosterone in your body.
You are dehydrated or you have low levels of fluid in your body.
You have gout, diabetes or have atherosclerosis (narrow blood vessels).
You will be taking anaesthesia or supposed to undergo any diagnostic tests.
You are elderly with impaired kidney function.

Mode of Action

How Does It Work?

It works by the combined action of Perindopril and Indapamide. Perindopril works by blocking the formation of certain chemicals responsible for tightening the blood vessels. This makes blood flow easier through the blood vessels.
Indapamide is a diuretic that works by removing excess water and salt from the body and which helps reduce blood pressure.

Interactions

Interactions with other medicines

Some medicines can affect the way this medicine works and this medicine itself can affect the action of other medicines.
Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
In particular, if you are taking medicines for brain-related conditions, anti-diabetics, blood pressure-lowering medicines, painkillers, medicines to modify immune response, steroids, anti-infectives, calcium supplements, medicines used to treat heart rhythm disorder etc.

Dosage

Overdose

An overdose of Indapamide+Perindopril can lead to an excessive drop in blood pressure accompanied by nausea, vomiting, cramps, dizziness, sleepiness and frequent urination. If you have taken too much of this medicine inform your doctor immediately or visit your nearest hospital.

Missed a Dose

You should never miss a dose of blood pressure-lowering medicine as missing a dose can lead to an increased risk of complications. Try to take the missed dose as soon as possible. Skip the missed dose if it is already time for the next dose and do not take two doses of this medicine together.

Frequently Asked Questions (FAQs)

Indapamide+Perindopril should be taken before meals preferably in the morning or as advised by your doctor.

It works by the combined action of its two active ingredients Perindopril and Indapamide. Perindopril works by inhibiting the formation of a chemical responsible for tightening blood vessels, hence reduces the blood pressure by making the blood flow easier. Indapamide removes excess fluid and salt from the body.