Clindamycin+Clotrimazole

Uses	Vaginal infections associated with vaginal discharge
Therapy	Anti-Fungal And Antibiotic
Side Effects	Burning sensation and irritation in the vagina, itching, pain while passing urine

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Molecule Description

Clindamycin+Clotrimazole is used to treat bacterial, fungal, and parasitic vaginal infections that are associated with vaginal discharge. It contains a combination of clindamycin and clotrimazole as its active ingredients. This medication works by inhibiting the growth of microorganisms that cause infections, thereby preventing the spread of the infection. Clindamycin+Clotrimazole is intended solely for vaginal use and is meant exclusively for women. It should be applied to the vagina as directed by your doctor. It is important to complete the entire course of treatment with this medication. Before using Clindamycin+Clotrimazole during pregnancy or while breastfeeding, it is advisable to seek medical advice.

Uses

Clindamycin+Clotrimazole is used for the treatment of different types of vaginal infections related to vaginal discharge. Vaginal discharge may be due to fungal, bacterial or parasitic infection or a mixture of them.

Contraindications

When should one not use Clindamycin+Clotrimazole

If you are allergic to clindamycin, clotrimazole or any other ingredients of Clindamycin+Clotrimazole.
If you have experienced diarrhoea with blood in stools, severe stomach pain and cramps after using an antibiotic or which are seen in some diseases of the intestines.

Side effects

Common side effects of this drug are:

Burning sensation, irritation in the vagina
Itching
Pain while passing urine

Precautions and Warnings

Pregnancy

Clindamycin+Clotrimazole should only be used during pregnancy if prescribed by your doctor, as there is limited safety information available. Your doctor will only prescribe this medicine if it is considered essential after assessing the benefits over risks. Also, ensure not to use an applicator when you are pregnant.

Breast Feeding

Clindamycin+Clotrimazole should be avoided while breastfeeding, as it passes into breast milk and may be harmful to the baby. Consult a doctor for other safer alternatives.

Driving

There is limited information about the effects of Clindamycin+Clotrimazole on driving.

Alcohol

There is no data regarding the interactions between Clindamycin+Clotrimazole and alcohol.

Other General Warnings

Talk to your doctor if

You experience an allergic reaction after using Clindamycin+Clotrimazole.
You may experience mild irritation and burning sensation in the vagina while inserting the suppository, please contact your doctor if your symptoms worsen or do not go away.
You do not notice any improvement in your condition after using this medicine for 3 days.
Clindamycin+Clotrimazole is meant only for vaginal use and should not be consumed.
You are advised to avoid intercourse even with condoms or vaginal diaphragms as the medicine can make them less effective.
You should also not use tampons, vaginal douches or other vaginal products while using this medicine.
You should preferably use cotton underwear.
Dry the area around the vagina after a bath and change damp clothing at the earliest. Wipe the area dry from front to back after visiting the toilet. Avoid scratching the area around the vagina.
If your partner has itching, redness or discomfort in the private parts, he should visit a doctor and inform about your treatment as well.
Do not use Clindamycin+Clotrimazole for any other conditions than that prescribed by your doctor.
Do not stop using this medicine without completing the treatment.
If this medicine is accidentally consumed, visit your doctor immediately or if it comes in contact with your eye, rinse thoroughly with cool water.

Mode of Action

How Does It Work?

Clindamycin+Clotrimazole works by the combined action of both its components - Clindamycin and Clotrimazole.
Clindamycin is an antibiotic that works by attaching to the genetic material of bacteria, thus preventing the production of substances required for their growth, it controls their spread.
Clotrimazole is an antifungal agent which works by attaching to the covering of the fungus cells. It destroys the covering and makes it porous. This slows the growth of the fungus and eventually kills it.

Interactions

Interactions with other medicines

Some medicines can affect the way Clindamycin+Clotrimazole works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
Other medicines like Atracurium, Vecuronium which are used to relax muscles before surgery, should be used with caution with this medicine as the duration of muscle relaxation may be increased.

Interactions with food items

It can be used without concern for dietary restrictions.

Dosage

Overdose

If you think you have used too much Clindamycin+Clotrimazole contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of Clindamycin+Clotrimazole, use it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not use a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

No, you should not stop using Clindamycin+Clotrimazole until it is advised by your doctor, even if you are feeling good. If you stop using it before completing the treatment your symptoms may return and your condition may also worsen.

No, you should visit a gynaecologist who will confirm if you have an infection or not after careful examination. Your gynaecologist may then prescribe you Clindamycin+Clotrimazole or any other appropriate medicine based on your infection and general health.

You are advised not to have intercourse till the duration of the treatment ends and until your gynaecologist approves it, as your partner may get the infection. Intercourse with protection is also not advisable as the medicine may react with the material of protection and break it, thus wasting its purpose.

Generally, most suppositories will melt in 10-15 minutes, although it can take up to half an hour. It may vary depending on a number of factors, like body temperature, the temperature of suppository prior to insertion, etc. If you still have any doubts, contact your doctor for more information.

No, you must keep using Clindamycin+Clotrimazole for the prescribed duration. Do not stop the treatment in between even if you feel improvement in symptoms, as incomplete treatment may result in treatment failure and the infection might reoccur.