Dextromethorphan+Chlorpheniramine / Chlorphenamine

Uses	Common cold and cough
Therapy	Cough Cold Preparation
Side Effects	Drowsiness, dizziness, upset stomach

3 Step Quality
Assurance

Cash on delivery
available

NPPA
Regulated

Molecule Description

Dextromethorphan+Chlorpheniramine / Chlorphenamine is a combination medication used to relieve cold symptoms, including cough, sneezing, and a runny nose. It contains chlorpheniramine, an antihistamine, and dextromethorphan, a cough suppressant. Chlorpheniramine works by blocking the receptors to which histamine binds, thereby preventing or reducing the allergic response. Cough is produced when the cough center in the brain is activated. Dextromethorphan acts as a cough suppressant by directly affecting these specific areas in the brain, essentially deactivating the cough reflex and providing relief from coughing. Chlorpheniramine tackles allergic symptoms at the source by blocking histamine, while dextromethorphan works on the central nervous system to suppress the cough reflex. This medicine should be taken exactly as prescribed by your doctor. Common side effects include nausea, upset stomach, and rash. These side effects are usually temporary, but contact your doctor if they persist or worsen. Dextromethorphan+Chlorpheniramine / Chlorphenamine may cause dizziness and drowsiness, so avoid driving or engaging in activities that require mental focus. Avoid alcohol consumption while taking this medication. Dextromethorphan+Chlorpheniramine / Chlorphenamine should not be used in children below 2 years of age. According to the advisory issued by the Union Health Ministry, cough and cold medications should not be prescribed or dispensed to children under two years of age. These medications are generally not recommended for children under five years old. For children above that age, any use should be based on careful clinical evaluation and close supervision.

Uses

Dextromethorphan+Chlorpheniramine / Chlorphenamine gives short-term relief from sneezing, cough, or runny nose due to minor throat and airway irritation which occurs during common cold and other respiratory allergies.

Contraindications

When should one not use Dextromethorphan+Chlorpheniramine / Chlorphenamine

In case you are allergic to chlorpheniramine, dextromethorphan or any other components of this medicine.
If you are having or had medicines like sodium oxybate (used to prevent day time sleepiness)
If you are taking or have taken monoamine oxidase inhibitors such as phenelzine, selegiline (used to treat mental illness or Parkinson's disease) at least two weeks before starting treatment with this medicine. In case you don't know whether your prescription includes such medicines, ask your doctor before taking Dextromethorphan+Chlorpheniramine / Chlorphenamine.

Side effects

Common side effects of this drug are:

Drowsiness
Sleepiness
Dizziness
Tiredness
Upset stomach
Headache
Nausea
Vomiting

Precautions and Warnings

Pregnancy

There is limited information available on the safety of Dextromethorphan+Chlorpheniramine / Chlorphenamine in human pregnancy. You should consult your doctor before using this medicine during pregnancy or if you think you may be pregnant. This medicine should be used only if it is needed and benefit outweighs the risk.

Breast Feeding

There is no safety information about the effects of Dextromethorphan+Chlorpheniramine / Chlorphenamine during breastfeeding. Thus, it is unknown if the components of Dextromethorphan+Chlorpheniramine / Chlorphenamine pass into human milk. You should consult your doctor before using during breastfeeding.

Driving

Dextromethorphan+Chlorpheniramine / Chlorphenamine produces blurring of vision and drowsiness as side effects. You should avoid driving if you do not feel well or are unable to stay alert.

Alcohol

Dextromethorphan+Chlorpheniramine / Chlorphenamine may produce drowsiness or sleepiness as a side effect, so if you consume it along with alcohol, it may exaggerate the drowsiness or sleepiness. Thus, you should avoid consuming alcohol while on treatment with this medicine.

Other General Warnings

Talk to your doctor if

You have a cough for a long time with a lot of mucus (like asthma, emphysema or smoking).
You have eye problems like glaucoma (increased pressure in the eye).
You have difficulty in urination and a frequent urge to urinate (enlarged prostate).
You have problems with your heart and liver.
You have any breathing problems, high blood pressure and fits.
In young children, this medicine may produce excitement instead of drowsiness. Be cautious while giving this medicine to children.
Older people should be cautious while using Dextromethorphan+Chlorpheniramine / Chlorphenamine, as they are more prone to develop dizziness and urination difficulties with this medicine.
It is not recommended to use this medicine in children below 2 years of age.

Mode of Action

How Does It Work?

Natural substances like Histamine released in our body are responsible for allergies such as sneezing or runny nose
Chlorpheniramine blocks the effect of these substances and provides relief in symptoms of a common cold
There are specific areas in the brain (cough centre) which when activated produces coughing
Dextromethorphan affects these areas and deactivates them, thus helps in relieving the coughing

Interactions

Interactions with other medicines

Dextromethorphan+Chlorpheniramine / Chlorphenamine should not be taken with a medicine called monoamine oxidase inhibitors (MAOIs) because it produces a condition called serotonin syndrome which is a life-threatening condition that can occur rapidly due to a build-up of an excessive amount of serotonin in the body.
In the case of serotonin syndrome, a person may experience high body temperature, high blood pressure, fast heart rate, excitability, tremor (shakiness), and sweating. In such a situation patients should rush to a nearby hospital.
Dextromethorphan+Chlorpheniramine / Chlorphenamine should be used cautiously with other medicines like Codeine, Hydrocodone (used for cough) that cause drowsiness. Alcohol, Marijuana, medicines to treat mental illness (Alprazolam, Lorazepam, Zolpidem, etc.), muscle-relaxing medicines ( Carisoprodol, Cyclobenzaprine), other antihistaminic medicines (Cetirizine, Diphenhydramine, etc.) should be consumed with caution.

Interactions with food items

Dextromethorphan+Chlorpheniramine / Chlorphenamine is taken with or without food in a dose and duration as advised by the doctor. Do not consume grapefruit juice or any other products which might have grapefruit juice.

Dosage

Overdose

Overdose of Dextromethorphan+Chlorpheniramine / Chlorphenamine may cause severe drowsiness, dizziness, fast or irregular heartbeats, confusion, hallucination, nervousness, seizures, fits and difficulty in releasing urine. If you experience any of the symptoms or think you have taken an excessive quantity of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

Missing a dose of Dextromethorphan+Chlorpheniramine / Chlorphenamine may reduce the effectiveness of the treatment. If you missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Patients suffering from prostate problems (benign prostatic hyperplasia) have symptoms like difficulty in passing urine, frequent urge to urinate and dribbling of urine. Dextromethorphan+Chlorpheniramine / Chlorphenamine contains a drug named chlorpheniramine which produces urine retention as a side effect. Thus it is advisable to talk to your doctor about your problem before using it.

No, you should not use Dextromethorphan+Chlorpheniramine / Chlorphenamine if you are taking medicines for mental illness.

No, one of the main ingredients in Dextromethorphan+Chlorpheniramine / Chlorphenamine is chlorpheniramine, which is an anti-allergic medicine and cetirizine is also an anti-allergic medicine. If you take cetirizine along with this medicine, it will aggravate the side effects of chlorpheniramine, especially drowsiness.

Dextromethorphan+Chlorpheniramine / Chlorphenamine should not be used in children below 2 years of age. Please refrain from using any medicines for your children without consulting a child specialist.

It can start showing its action approximately after 2 hours of consumption. However, it varies among individuals depending on their physiological nature.

Dextromethorphan+Chlorpheniramine / Chlorphenamine contains chlorpheniramine, it increases the pressure in the eye and thus decreases the effectiveness of glaucoma medicines. So it is always advisable to talk to your doctor about your eye problem before using this medicine.

Yes, Dextromethorphan+Chlorpheniramine / Chlorphenamine can make you feel sleepy and drowsy. Thus, it is recommended that you avoid driving and doing activities that need mental alertness after taking this medicine.

You should take Dextromethorphan+Chlorpheniramine / Chlorphenamine in the dose and duration as prescribed by your doctor. Do not take an excess dose as it may cause undesired effects. Inform your doctor if your symptoms do not ease or there is a relapse with headache, fever, and rash even after using the medicine for 7 days.

Dextromethorphan+Chlorpheniramine / Chlorphenamine should not be used during breastfeeding, as there is no sufficient data about whether the medicine passes through the breastmilk.

Dextromethorphan+Chlorpheniramine / Chlorphenamine might cause few side effects in some individuals, such as nausea, stomach upset, tiredness, drowsiness, etc. If you feel such symptoms persistently, contact your doctor.

It is advised not to take any anti-allergic medicine along with this medicine unless prescribed by the doctor.

Dextromethorphan+Chlorpheniramine / Chlorphenamine should be taken in exact dose and duration prescribed by the doctor. It can be taken with or without food. But it is advised not to abruptly stop the treatment, otherwise symptoms might reappear.

No, Dextromethorphan+Chlorpheniramine / Chlorphenamine contains a combination of chlorpheniramine and dextromethorphan, as its active component.

Do not give this medicine to your child on your own. The dose will be decided by the child's doctor on the basis of the child's age and body weight. Do not self-medicate any medicine to children. Please consult a doctor before giving medicine to your child.

The composition of Dextromethorphan+Chlorpheniramine / Chlorphenamine consists of a combination of chlorpheniramine and dextromethorphan. Chlorpheniramine is an anti allergic medicine whereas dextromethorphan is a cough suppressant.

Dextromethorphan+Chlorpheniramine / Chlorphenamine gives short-term relief from sneezing, cough or runny nose due to minor throat and airway irritation which occurs during common cold and other respiratory allergies.

There is limited information available on the effect of Dextromethorphan+Chlorpheniramine / Chlorphenamine in pregnancy. You should consult your doctor before using this medicine during pregnancy or if you think you may be pregnant. This medicine should only be used if recommended by your doctor after assessing the need and the risk.

Dextromethorphan+Chlorpheniramine / Chlorphenamine is a cough and cold preparation that is used for temporary relief of cough due to throat irritation, sneezing and running nose which occurs during common cold and other respiratory allergies.

Yes, Dextromethorphan+Chlorpheniramine / Chlorphenamine can be used for the treatment of dry cough. However, you should only use this medicine if it is recommended by your doctor. Do not use this medicine on your own.

Yes, Dextromethorphan+Chlorpheniramine / Chlorphenamine is safe if taken in the dose and duration as advised by your doctor. You should not take this medicine for longer periods or in a larger dose than prescribed.