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Sorafenat 200mg Bottle Of 30 Tablets

By NATCO PHARMA LTD

30 Tablet(s) in Bottle

MRP ₹2350.00

₹2021.0014% OFF

Inclusive of all taxes

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Sorafenat 200 MG Description

Sorafenat tablets belong to the group of anti-cancer medicines. Primarily treating the cancers of the kidney, thyroid, and liver is the main use of Sorafenat tablets. Tumours or cancers happen when h

ealthy cells of the various organs become malignant (cancerous) and grow in an uncontrolled manner. The active component of this medication is Sorafenib. Omeprazole is an antacid, and Domperidone prevents nausea and vomiting. The mode of action of Sorafenat tablets is to block the activity of various enzymes, which lowers the growth and multiplication of tumour cells. It also stops the spread of tumour cells. Weight loss, decreased appetite, stomach and abdominal pains, high blood pressure, etc., are some of the most common side effects of Sorafenat tablets. Follow your doctor’s directions for using the Sorafenat tablet. Do not stop using this medicine without consulting your doctor. Before taking it, tell the doctor about any heart disease, liver, or kidney problems. Many other medicines can affect or be affected by this medicine so let the doctor know the patient's complete medical history. It is not recommended in pregnancy or during breastfeeding.

Product Summary

Offer Price	₹2021.00
You Save	₹329.00 (14% on MRP)
Contains	Sorafenib(200.0 Mg)
Uses	Liver cancer, Kidney cancer, Thyroid cancer
Side effects	diarrhoea, fatigue, infection, alopecia, hand-foot skin reaction, rash, weight loss, decreased appetite, nausea, stomach and abdominal pains, hypertension, and bleeding.
Therapy	ANTI-NEOPLASTIC

Check more medicines with composition as Sorafenib(200.0 Mg)

Precautions and Warnings

Uses of Sorafenat 200 MG

As per CDSCO and USFDA, Sorafenat tablet is indicated for the treatment of the following condition:
It is indicated for the treatment of liver cancer carcinoma in cases where surgical removal is not possible.
In the treatment of advanced-stage renal cell carcinoma (kidney cancer).
In various types of locally recurrent or metastatic, progressive, differentiated thyroid cancer that didn't respond to radioactive iodine treatment.

Contraindications of Sorafenat 200 MG

If you have a history of serious hypersensitive reactions to Sorafenib or other similar medications. Serious reactions require immediate emergency treatment with supportive measures.
If you are using other types of anti-cancer medications such as carboplatin or paclitaxel.
If you are having a sudden heart condition such as heart attack, congestive heart failure, or any cardiovascular event.
If you are experiencing severe bleeding or have a history of a bleeding disorder.
If you have a history of high blood pressure. Monitor blood pressure weekly during the first 6 weeks and regularly thereafter.
If you have severe or persistent skin conditions such as Stevens-Johnson syndrome and toxic epidermal necrolysis are suspected.
If you have a stomach or intestinal perforation.
If you have a heart rhythm disorder such as QTc prolongation. Regular monitoring is required for people who are at risk.
If you are diagnosed with liver failure due to medications.
If you are currently expecting or planning to get pregnant.

Side effects of Sorafenat 200 MG

Hair loss
Hand-foot skin reaction
Weight loss
Decreased appetite
Stomach and abdominal pains
High blood pressure
Excessive bleeding

Precautions and Warnings of Sorafenat 200 MG

Pregnancy

Can I take the Sorafenat 200 mg tablet during pregnancy?

No, Sorafenat tablets can be unsafe to use in pregnant women. There is not enough information and well-controlled studies available on the safety of Sorafenat tablets in pregnant women. A few studies have shown that this medicine can cause harm to the foetus. These tablets should be used during pregnancy only if needed. Please consult your doctor before using them.

Breast Feeding

Can I take the Sorafenat 200 mg tablet while breastfeeding?

There is not enough data present on the effects of Sorafenat tablets in nursing women. The safety of Sorafenat tablets in breastfed infants is clearly established. Consult your doctor before using these tablets.

Driving

Can I drive if I have taken the Sorafenat 200 mg tablet?

There is no information present on the effects of Sorafenat tablets while driving. If you notice any side effects that may affect your driving ability, do not drive.

Alcohol

Can I consume alcohol with the Sorafenat 200 mg tablet?

There is not enough data available on the effects of alcohol on Sorafenat tablets. Avoid drinking high amounts of alcohol which can increase the side effects of Sorafenat tablets, such as nausea, vomiting, and stomach pain.

Other General Warnings

Talk to your doctor if

You have a severe kidney or liver illness.
You have a history of myocardial infarction (blockage in the arteries of the heart).
You are using blood thinners such as warfarin.
You recently had surgery and have wound healing complications.
You have any type of seizure disorder and are currently under treatment for it.
You are an elderly patient over the age of 65.
You have fluctuating levels of blood glucose or are a diabetic patient.
You experience any weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black coloured stools.
You are at risk of aneurysms or other blood vessel disorders.
You are using thyroid replacement therapy along with treatment for thyroid cancer.

Mode of Action of Sorafenat 200 MG

How Does It Work?

Sorafenat tablets contain Sorafenib as their main ingredient. Sorafenib belongs to the class of medications called kinase inhibitors. It works by stopping the action of an abnormal protein, such as s...

Directions for Use of Sorafenat 200 MG

Take Sorafenat tablets just as the doctor prescribed to you.
Do not change the dose of Sorafenat tablet, even if you do not see its effects.
Swallow this pill as a whole with a glass of water. Do not break or chew it.
It is better to not take it with other medications without informing your doctor.
Do not use Sorafenat medicine if its packaging has been already opened.
Do not suddenly stop taking the Sorafenat tablet, as it can cause adverse effects from withdrawal.
Try to take these without food (at least 1 hour before or 2 hours after eating) to prevent low absorption of the medicine.

Interactions of Sorafenat 200 MG

Interactions with other medicines

Using Sorafenat tablets within five days of administration of rifampicin results in a decrease in the levels of Sorafenat tablets, which lowers their effectiveness.
It is not recommended to use other anticancer medicines such as paclitaxel and carboplatin along with Sorafenat tablets. Studies have shown that levels of all these medicines are increased, which can ...
Read more
Other medications such as St. John's wort, phenytoin, carbamazepine, phenobarbital, and dexamethasone may also increase the metabolism of Sorafenat tablets and thus decrease its concentrations.
Inform your doctor if you are taking blood thinners such as warfarin with Sorafenat tablets. Patients should have their INR (test to check the time for the blood to clot) checked regularly.
Using Sorafenat tablets along with digoxin can increase the plasma levels of digoxin, which can lead to several side effects such as confusion, dizziness, etc.

Interactions with food items

Avoid any foods that increase the sense of nausea or vomiting, such as meat, fish, eggs, or dairy, while using Sorafenat tablets due to their strong odour.
Food also lowers the absorption of Sorafenat tablets, resulting in a decrease in its effectiveness.

Storage and disposal of Sorafenat 200 MG

Store Sorafenat tablets in dry conditions and at room temperature. Keep these medicines away from wet surfaces, direct sunlight, and humid conditions. Keep Sorafenat tablets away from children and pet...

Dosage of Sorafenat 200 MG

Overdose

Overdose symptoms due to an excess amount of Sorafenat tablet can include adverse effects such as chest pain, shortness of breath, feeling lightheaded, fainting, nausea, vomiting, sweating a lot, and ...

Missed a Dose

If you have missed a dose of Sorafenat tablet, take it as soon as you recall. If you remember when it is already time to take the next dose of Sorafenat tablet, take the scheduled dose and skip the mi...

Content Details

WRITTEN BY

Dr. Aashritha Pilli

MBBS

REVIEWED BY

Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)

Q: Can Sorafenat tablets cause any problems with heart rate or rhythm if I use them regularly?

A: One of the more serious side effects of Sorafenat tablets is that they can lead to an increased risk of irregular heartbeat (such as arrhythmias). It can also cause high blood pressure and changes in ECG (electrocardiogram). The chances that this side effect may happen are very low. The risk can be slightly higher in patients who are over 65 years of age.

Q: How do I know if I am responding to Sorafenat 200 mg tablets?

A: While undergoing the treatment with Sorafenat Tablet, your doctor will most likely advise you to get regular scans to monitor the growth and size of the tumour. You may also need to get blood tests done regularly to see if the liver or kidney functions have improved or not.

Q: What is the best time for me to take the Sorafenat tablet?

A: Sorafenat tablets should be stopped in case you have experienced a serious side effect that affects the quality of life. Or else, you need to keep using the Sorafenat tablet until your doctor asks you to stop it.

References

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Product Details

Brand

SORAFENAT

Country of Origin

India

Expires on or After

24/07/2024

Manufacturer Details

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Last Updated on: 16 Apr 2022 | 05:25 PM (IST)

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