Reluease Strip Of 10 Tablets

• Treatment of moderate to severe symptoms of uterine fibroids (myomas)
• Reduction of heavy menstrual bleeding associated with uterine fibroids
• Relief of pelvic pain and discomfort due to fibroids
• Symptomatic treatment of endometriosis in women with a history of previous medical or surgical treatment
• Reduction of pelvic pain, dysmenorrhoea, and pain associated with endometriosis

• If you are allergic to relugolix, estradiol, norethisterone acetate, or any of the ingredients
• If you have or have had venous thromboembolic disorders (such as deep vein thrombosis or pulmonary embolism)
• If you have or have had arterial thromboembolic disease (such as a heart attack, stroke, or ischemic heart disease)
• If you have known thrombophilic disorders (such as protein C, protein S, or antithrombin deficiency, or Factor V Leiden)
• If you have known osteoporosis
• If you have migraine with aura or headaches with focal neurological symptoms
• If you have known or suspected sex-steroid influenced malignancies (such as breast or genital organ cancers)
• If you have liver tumors, whether benign or malignant
• If you have severe liver disease and your liver function values have not returned to normal
• If you are pregnant or breastfeeding
• If you have genital bleeding of an unknown cause
• If you are currently using other hormonal contraceptives

• Headache
• Hot flush
• Irritability
• Dizziness
• Nausea
• Hair loss
• Increased sweating
• Night sweats
• Joint pain
• Excessive, irregular or prolonged uterine bleeding
• Dryness of the genital area

Other General Warnings

• You have or have ever had a blood clot in your legs, lungs, heart or brain
• You have risk factors for venous thromboembolism such as obesity, prolonged immobilisation, major surgery or a family history of blood clots
• You have high blood pressure
• You have migraine, especially migraine with aura
• You have a history of liver disease or abnormal liver function tests
• You have liver tumours or a history of liver tumours
• You have osteoporosis or risk factors for bone loss
• You have unexplained vaginal bleeding
• You have or have had hormone-dependent cancers (such as breast or genital cancers)
• You have been told you have an intolerance to some sugars (as this medicine contains lactose)
• You are scheduled for major surgery or expect prolonged immobilisation
• You are pregnant, think you may be pregnant or are planning to become pregnant
• You are breastfeeding
• You are taking any other medicines, including herbal products such as St John’s Wort
• You have kidney problems
• You have had a kidney transplant

• Take Reluease tablet as prescribed by your doctor.
• Take at about the same time each day
• Can be taken with or without food
• Swallow with some liquid

• Keep out of the sight and reach of children
• Do not use after the expiry date
• This medicine does not require any special storage conditions
• Do not throw away via wastewater or household waste

Overdose

• Taking too much of this medicine can lead to symptoms caused by large doses of estrogen, such as nausea, vomiting, or vaginal bleeding. it is important to be aware of these potential reactions.
• If you accidentally take more than the recommended daily dose, you should consult your doctor or pharmacist for further medical advice.

Missed a Dose

• If you miss one tablet, take it as soon as possible and resume your usual schedule the next day.
• Do not take a double dose to make up for a forgotten tablet.
• If you miss two or more tablets in a row, consult your doctor and use a nonhormonal contraceptive (such as condoms) for the next 7 days of treatment.

How Does It Work?

Interactions with other medicines

• Several medications can affect how this treatment works. It is not recommended to use it alongside strong CYP3A4 and P-gp inducers, such as rifampicin, as these can significantly reduce the effectiveness of the medicine.
• Certain herbal remedies like St. John’s Wort should be avoided or used with caution because they can also interfere with the treatment's stability.
• Caution is advised when taking this medication with CYP3A4 inhibitors like ketoconazole, or with various enzyme inducers such as phenobarbital, phenytoin, and carbamazepine.
• You should also notify your doctor if you are taking specific cardiovascular medicines, including ranolazine, carvedilol, or verapamil, or treatments for infections and organ transplants like ritonavir, telaprevir, or cyclosporine.

Interactions with food items