Osartil 50 Plus Tablet

• If you are allergic to Losartan, Hydrochlorothiazide, or any of the ingredients of this medicine.
• If you are allergic to sulfonamide medicines such as co-trimoxazole.
• If you have a low level of potassium & sodium or high levels of calcium in your blood
• If you have serious liver disorders and problems related to the bile duct (a canal connecting the liver to intestine) like cholestasis.
• If you have anuria (not passing urine or passing urine less than 100ml in a day).
• If you have diabetes or kidney problems and taking medicine for high blood pressure like Aliskiren.
• If you have gout.
• If you are pregnant for more than 3 months.

• Cough
• Nasal congestion
• Nausea
• Diarrhoea
• Stomach pain
• Chest pain
• Headache
• Weakness
• Dizziness

Other General Warnings

• You have any kind of pre-existing health condition such as heart-related disorder, diabetes, kidney or liver disorder, skin cancer, gout, an autoimmune disorder like systemic lupus erythematosus, etc.
• You develop symptoms like swelling of the face, lips, throat or tongue due to water retention.
• You experience fainting and giddiness, especially after the first dose.
• You are planning a pregnancy, this medicine will be changed.
• Your kidneys are not functioning correctly or you have underlying kidney disease like renal artery stenosis (Narrow kidney blood vessels).
• You have been experiencing fluid losses within your body due to diarrhoea, vomiting, etc.
• You are suffering from primary aldosteronism (a condition of excess production of the hormone aldosterone from the adrenal glands).
• You have electrolyte imbalance of sodium, magnesium, potassium and have symptoms of dryness of mouth, thirst, drowsiness, muscle pain, nausea, vomiting, etc.
• You have galactose intolerance (small intestine's inability to transport and absorb glucose and galactose).
• You develop eye pain and a decrease in vision.

• This medicine should be consumed as a whole with a sufficient amount of water with or without food.
• Do not change your dose unless your doctor tells you to do. Never stop this medicine on your own.
• This medicine tends to catch moisture and should be taken out from blister just before use.

• Store this medicine below 30°C.
• Keep this medicine in the original container to protect it from light and moisture

Overdose

Missed a Dose

• It would be best if you never miss a dose of your blood pressure medicine as it may lead to serious high blood pressure-related problems.
• If you have missed taking any dose, take it as soon as you remember. If it is time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of this medicine to compensate for the missed one

How Does It Work?

• Telmisartan lowers blood pressure by blocking the action of a hormone called angiotensin responsible for the narrowing of blood vessels and rise in blood pressure.
• Hydrochlorothiazide acts by increasing the production of urine and loss of water and salt from the body, thereby lowering the blood pressure. Both the medicines act by different mechanisms resulting in effective control of blood pressure.

Interactions with other medicines

• Sometimes the Osartil 50mg Plus Tablets may interact with other medicines or vice versa. Therefore, discuss with your doctor about all the medicines, supplements or herbal preparations you are taking.
• Especially, if you are on certain medications like blood thinners (warfarin or heparin), anti-cancer medicines, medicines used to treat high cholesterol such as cholestyramine, anti-depressants like lithium, potassium supplements or medicines containing potassium, other anti-hypertensives like water pills (furosemide), medicines for heart-related disorders like digoxin, etc.
• If you have diabetes, do not take aliskiren along with this medicine.
• Steroidal medicines if taken along with this medicine can lead to salt imbalances particularly reduced potassium levels.
• Concomitant use of the Osartil 50mg Plus Tablets and painkillers should be avoided as it may impair kidney functions.
• Other medicines that should be used with caution are anti-bacterial medicines such as Trimethoprim, corticosteroids used to treat the inflamed area of body parts, etc.
• Also, you should inform your doctor if you have a planned surgery or vaccination scheduled.

Interactions with food items