Metbetic GL 2 Tablet

• If you are allergic to metformin, glimepiride or any of the ingredient of Metbetic Gl Tablet.
• If you are pregnant or breastfeeding.
• If you have serious kidney failure or liver failure.
• If you have any metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma
• If you have dehydration, severe infections, shock and injections containing iodine
• If you have had heart or lung failure, recent incidence of heart attack and shock
• If you are alcoholic.

• Nausea
• Vomiting
• Diarrhoea
• Abdominal pain
• Loss of appetite
• Metallic taste
• Headache
• Hunger pangs
• Sleepiness
• Restlessness

Other General Warnings

• You experience extreme hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness, confusion, shakiness or dizziness. These could be signs of low blood sugar.
• You are going to have a diagnostic imaging test which involves injection of iodine.
• You have dehydration due to diarrhoea, vomiting or limited fluid intake.
• You have a planned surgery.
• You have serious kidney and liver problems.
• You have thyroid disorder.
• You are overweight (specific diet restriction may be suggested).
• Long term use of this medicine can cause low level of vitamin B12, which may result in tingling, pins-and-needles sensation, numbness and weakness.

• Store at room temperature in a dry place. Protect it from light and moisture.
• Keep out of the reach of children and pets.

• Take Metbetic GL2 Tablet PR exactly as prescribed by your doctor.
• Take the tablet with meals, preferably with the first meal of the day.
• Take it at the same time each day for consistent blood sugar control.
• Do not skip doses or stop the medicine without consulting your doctor.
• Inform your doctor if you are pregnant, planning pregnancy, breastfeeding, or have other medical conditions.
• Monitor your blood sugar regularly as advised by your doctor.
• Maintain a healthy diet and exercise regularly to support treatment.
• Common side effects may include mild nausea, dizziness, or headache; contact your doctor if severe or persistent.
• Avoid alcohol or limit intake, as it can affect blood sugar levels.

Overdose

• Overdose of Metbetic Gl Tablet may lead to severe hypoglycemia (low blood sugar) and lactic acidosis (excessive lactic acid build-up). This can result in headache, nausea, vomiting, sleep disturbances, restlessness, impaired alertness and reactions, low mood, confusion, dizziness etc.
• If you experience these, immediately take glucose or juice or sugar-containing products (Sugar candy).
• Contact your doctor immediately or visit the nearest hospital as you may require close monitoring for the next few hours.

Missed a Dose

• Missed dose may lead to high blood sugar levels, which includes symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, fruity smell from breath etc.
• If you missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

How Does It Work?

• Glimepiride lowers the blood sugar level by increasing release of insulin hormone from pancreas. Insulin moves sugar (glucose) from the blood into the cells.
• Metformin decreases the absorption in the intestine and production of sugar by the liver.
• Both of these components are known to increase the insulin sensitivity of the body (allows the cells of the body to use blood glucose more effectively, reducing blood sugar).

Interactions with other medicines

• Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• Especially if you are taking medicines to treat high blood pressure, heart failure, high/abnormal cholesterol levels, blood thinners, anti-infectives, thyroid medicine anti-diabetics, anti-asthmatics, oral contraceptives, pain killers, immunomodulatory medicines or medicines for the brain-related disorder.
• Medicines used for acidity like ranitidine, anti-hypertensive medicine like atenolol, propanolol, clonidine and anti-pyschotic medicine like reserpine can either increase or decrease the effect of this medicine, thus masking the signs of low blood sugar, thus should be cautious.

Interactions with food items

• Take Metbetic GL2 Tablet PR with meals, especially the first meal of the day, to reduce stomach upset.
• Eat regular, balanced meals with controlled portions of carbohydrates to maintain stable blood sugar levels.
• Include plenty of vegetables, whole grains, and lean proteins in your diet.
• Avoid sugary foods and drinks, such as sweets, desserts, and soft drinks, which can raise blood sugar.
• Limit alcohol, as it can increase the risk of low blood sugar and interfere with treatment.
• Avoid skipping meals, which can cause low blood sugar, especially when taking glimepiride.
• Stay hydrated by drinking enough water throughout the day.
• Discuss any herbal supplements or over-the-counter medicines with your doctor, as they may interact with your diabetes medication.
• Eating smaller, frequent meals may help reduce spikes in blood sugar.