Mesacol Tablet
Description
Mesacol 400 tablet is a medicine that helps manage ulcerative colitis, a condition that causes inflammation and sores in the lining of the large intestine. It contains mesalazine, also known as mesalamine or 5-aminosalicylic acid, as its main ingredient. This medicine works by reducing inflammation in the intestines, helping relieve symptoms like pain, diarrhoea, and rectal bleeding.
Taking Mesacol 400 regularly as prescribed by your doctor can help control symptoms and prevent flare-ups of ulcerative colitis. It is important not to stop taking it suddenly, even if you feel better, as this can cause symptoms to return. Always follow your doctor’s instructions carefully regarding the dosage and timing of the tablet.
This medicine should be swallowed whole with water and not crushed or chewed, as it is designed to release the medication slowly in your intestines. It can be taken with or without food, but taking it with food may help reduce stomach discomfort. Try to take it at the same time every day to maintain steady levels of medicine in your body.
Mesacol 400 may cause mild side effects such as nausea, headache, abdominal pain, or diarrhoea in some people. These effects are usually temporary, but if they persist or worsen, contact your doctor immediately. Also, inform your doctor if you notice any unusual tiredness, yellowing of the skin, or dark urine, as these could be signs of liver or kidney problems.
Before starting Mesacol, let your doctor know if you have any kidney, liver, or heart problems, or if you are pregnant or breastfeeding. It is not recommended for children under 6 years of age. Always take this medicine exactly as advised by your healthcare provider for the best results and to prevent complications.
Product Summary
| Offer Price | ₹95.18 |
| You Save | ₹31.72 (25% on MRP) |
| Contains | Mesalazine / Mesalamine / 5-Aminosalicylic Acid(400.0 Mg) |
| Uses | Ulcerative colitis |
| Side effects | Skin rash, itching, indigestion, fever |
| Therapy | DRUGS FOR ULCERATIVE COLITIS |
Uses
Contraindications
- If you are allergic to mesalazine or any other ingredients of Mesacol 400 tablet.
- If you have any problems with your liver or kidney.
- If you are allergic to salicylates (Diclofenac, aspirin, Ibuprofen, etc).
- If your child is below the age of 6 years.
Side effects
- Skin rash, itching
- Indigestion
- Fever
- Chest pain
- Numbness, tingling or pricking sensation
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have any liver or kidney related problems.
- You have any lung diseases like asthma.
- You have any problems with your heart (like any allergic reactions).
- You have experienced an allergic reaction while taking sulfasalazine.
- You may develop kidney stones (symptoms like stomach pain, blood in urine) while on treatment with this medicine. Hence you should drink plenty of water.
- Before and during treatment with Mesacol 400 tablet, your doctor may want to monitor the liver, kidneys, blood and lungs periodically.
- Mesacol 400 tablet is not recommended for use in children less than 6 years old.
Directions for Use
Storage and disposal
Quick Tips
- Take the tablet exactly as prescribed by your doctor and don’t skip doses.
- Swallow the tablet whole with water; do not crush or chew it.
- Try to take it at the same time every day for the best results.
- Drink plenty of fluids to stay hydrated while on this medicine.
- Take it with food if you feel any stomach discomfort.
- Inform your doctor if you experience nausea, vomiting, or severe abdominal pain.
- Avoid stopping the medicine suddenly without consulting your doctor.
- Let your doctor know if you have any kidney or liver problems.
- Keep the tablets in a cool, dry place away from direct sunlight.
- Do not give this medicine to children under 6 years unless prescribed.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- You should always tell the doctor if you are taking any other medicines, herbal preparation and supplements to avoid any interaction with Mesacol 400 tablet.
- You need to be cautious while simultaneously taking this medicine along with medicines like azathioprine, 6-mercaptopurine (used in rheumatoid arthritis, Crohn's disease), thioguanine (used in cancer treatment)....
- This medicine when taken along with blood thinners like warfarin (used to prevent blood clot formation) may decrease the effect of warfarin.
Interactions with food items
Content Details
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: How long to take Mesacol 400 tablet?
Q: My brother has similar symptoms can I recommend the same Mesacol to her?
Q: Can I stop taking Mesacol 400 tablet if I feel better?
Q: What should I discuss with my healthcare expert before taking Mesacol 400 tablet?
- Inform the doctor about your detailed medical & surgical history.
- Inform your doctor if you have heart, liver or kidney disease.
- Inform your doctor if you are pregnant, breastfeeding or planning to have a baby.
- This medicine may interact with other medicines, hence, inform your doctor if you are taking any other medicines including supplements or herbal products. Also, inform your doctor if you are stopping any medicine....
Q: Is Mesacol 400 tablet addictive?
Q: What is Mesacol used for?
References
- Octasa 400 mg Modified Release Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 2 May 2022]
- Octasa 400 mg Modified Release Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 2 May 2022]
- CDSCO [Internet]. Cdscoonline.gov.in. 2021 [cited 2 May 2022]
- Iacucci M, de Silva S, Ghosh S. Mesalazine in inflammatory bowel disease: a trendy topic once again? Can J Gastroenterol. 2010 Feb [cited Jan 2025]
- Schroeder KW. Role of mesalazine in acute and long-term treatment of ulcerative colitis and its complications. Scand J Gastroenterol Suppl. 2002 [cited Jan 2025]
- Gisbert JP, Gomollon F, Mate J, et al. Role of 5-aminosalicylic acid (5-ASA) in treatment of inflammatory bowel disease: a systematic review. 2002 [cited Jan 2025]
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