Diprogen Cream
Description
Diprogen cream is a medication used to treat various skin conditions, including eczema, psoriasis, dermatitis, fungal infections such as ringworm or athlete's foot, and bacterial skin infections. It combines three active ingredients: betamethasone, clotrimazole, and gentamicin. They work together to reduce inflammation, fight fungal infections, and kill bacteria causing skin issues.
Betamethasone helps by reducing swelling, redness, and itching caused by inflammation or allergic reactions. Clotrimazole works by damaging the protective layer of fungi, leading to their death and stopping the infection. Gentamicin stops bacteria from growing by blocking the production of proteins they need to survive, helping to clear bacterial skin infections.
This medication is meant for external use only. It should be applied to clean, dry skin. Hands should be washed before and after use. Avoid covering the treated area with bandages unless directed to do so by a doctor, and keep it away from your eyes. Some mild side effects may include burning, itching, redness, or acne-like breakouts; however, these usually subside on their own.
It is important to follow your doctor’s instructions while using this medication. Do not use it for longer than recommended, especially on sensitive areas like the face or in children. Let your doctor know if your skin condition worsens, if you have kidney issues, or if you experience unusual reactions. Also, inform your doctor about any other medicines you're using, even though skin creams generally do not cause major interactions.
Product Summary
Offer Price | ₹35.20 |
You Save | ₹4.80 (12% on MRP) |
Contains | |
Uses | Bacterial infection |
Side effects | Burning, itching, irritation, and dryness at the application site |
Therapy | TOPICAL ANTIMICROBIAL AND STEROID |
Uses
Contraindications
Side effects
- Burning or stinging sensation on the skin
- Itching or irritation at the application site
- Skin dryness or peeling
- Redness or rash (erythema)
- Folliculitis (inflamed hair follicles)
- Acne-like breakouts
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- Your infection does not improve, spread, or worsen while using the medication.
- You need to use the medication for an extended period, especially on the face or in children, as it may thin the skin or affect hormone levels.
- You have kidney problems or notice hearing issues, since gentamicin can affect the kidneys and ears.
- You get medication in your eyes, rinse thoroughly and seek medical attention if irritation persists.
- You may develop skin irritation, allergies, or unusual reactions after repeated or prolonged use.
Directions for Use
- It is meant for external use only.
- Clean and dry the area to be treated, and apply the cream to the affected area.
- Wash your hands before and after using this cream unless your hands are the area to be treated.
- Avoid applying under an occlusive bandage.
- If your eyes come into contact with this cream, rinse them immediately with clean water.
Storage and disposal
- Store Diprogen cream in a cool and dry place. Do not freeze it.
- Keep it out of reach and sight of children and pets.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
- Betamethasone works by reducing inflammation in the body. It is a corticosteroid that blocks the production of certain chemicals (like prostaglandins and leukotrienes) that cause swelling, redness, itching, and allergic reactions. By doing this, it helps relieve symptoms of conditions such as eczema, psoriasis, and other inflammatory skin disorders....
- Clotrimazole works by stopping the growth of fungi. It damages the fungal cell membrane by blocking the production of a substance called ergosterol, which is essential for the fungi's survival. Without ergosterol, the cell membrane becomes weak, causing the contents to leak out and the fungus to die. This helps treat infections like athlete’s foot, ringworm, and candidiasis....
- Gentamicin works by inhibiting the production of proteins that bacteria require for growth and survival. It attaches to a part of the bacterial cell called the ribosome, which is responsible for protein production. By disrupting this process, gentamicin causes the bacteria to produce faulty proteins, leading to their death and helping clear the infection....
Interactions
Interactions with other medicines
Content Details

Ravindra Ghongade
B. Pharm

Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: Can I use Diprogen cream on broken or infected skin?
Q: Can I use Diprogen cream for other types of infections?
Q: Can I use makeup or other skin products with Diprogen cream?
References
- National Agency for Food and Drug Administration and Control (NAFDAC). Summary of Product Characteristics for Digicloge Cream [Internet]. Abuja: NAFDAC; 2023 May 27 [cited 2025 Jun 24].
- Central Drugs Standard Control Organisation. Drugs [Internet]. New Delhi: Ministry of Health and Family Welfare, Government of India; [cited 2025 Jun 24].
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