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Depran L Tablet

10 Tablet(s) in Strip
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Depran L Tablet Description

Depran L Tablet is used for the treatment of depression & anxiety disorders. Anxiety and other mood disorders affect how you feel. They are characterised by excessive, unrealistic worry and fear that

can interfere with daily activities, and it is often accompanied by major depressive disorder. Depran L Tablet helps the relaxing mood by lowering the excess activity of nerves in the brain. It can also cause a sedation effect which relieves anxiety and improve sleep. Depran L Tablet contains Clonazepam and escitalopram as their active ingredient. Depran L Tablet should be taken in dosage and duration as advised by your doctor. Do not stop taking this medicine suddenly without consulting your doctor, as it can cause clinical worsening of your condition or may lead to withdrawal symptoms.


Product Summary

Offer Price₹115.60
You Save₹20.40 (15% on MRP)
ContainsCitalopram(5.0 Mg) + Clonazepam(0.25 Mg)
UsesTreatment of Anxiety Disorder and Depression.
Side effectsNausea, Increased sweating, Fatigue, Confusion, Drowsiness, Insomnia, Sexual dysfunction.
Check more medicines with composition as Citalopram(5.0 Mg) + Clonazepam(0.25 Mg)

Uses of Depran L Tablet

  • As per CDSCO and USFDA, Depran L is used in the treatment of Anxiety disorder and depression.

Contraindications of Depran L Tablet

  • You are allergic to any of the components of the Depran L Tablet.
  • You are taking Monoamine Oxidase Inhibitors (MAOIs) and antipsychotic medicine-pimozide.
  • You are already using other anti-anxiety or sedatives.
  • You have acute angle glaucoma, which increases the fluid pressure in the eyes.
  • You have liver disease.
  • You have kidney disease.
  • You have respiratory issues.
  • You have a heart condition.
  • You are pregnant and a lactating mother.

Side effects of Depran L Tablet

  • Nausea
  • Increased sweating
  • Fatigue
  • Confusion
  • Drowsiness
  • Insomnia
  • Sexual dysfunction (decreased libido, anorgasmia, and male ejaculatory delay)

Precautions and Warnings of Depran L Tablet



Can I take Depran L Tablet during pregnancy?
Depran L Tablet is not recommended during pregnancy. Some research studies have shown harmful effects of the medicines on the developing foetus(baby). Pregnant women are advised to take this medicine only if it is recommended by their doctor. The doctor will weigh the benefits and potential risks before prescribing the medicine.

Breast Feeding

Can I take Depran L Tablet while breastfeeding?
Depran L Tablet is not recommended during breastfeeding. It gets excreted into breast milk and can affect the baby. Consult your doctor and discuss the potential risks and benefits of Depran L Tablet. Your doctor may advise you to discontinue breastfeeding or prescribe low doses if you continue breastfeeding.


Can I drive if I have taken Depran L Tablet?
Depran L Tablet may cause side effects that could affect your ability to drive. The tablet may decrease alertness, affect your vision and can cause dizziness, lethargy, lightheadedness. Do not drive if you are experiencing these side effects after taking this medicine.


Can I consume alcohol with the Depran L Tablet?
No, do not consume alcohol with Depran L Tablet. It increases the severity of side effects like drowsiness, dizziness, blurred vision, lethargy, liver injury, etc. It also worsens the condition of the disease for which you are taking this tablet.

Other General Warnings

Talk to your doctor if
  • You have any allergic reactions after taking Depran L Tablet.
  • You have any suicidal ideation or self-harming thoughts.
  • You experience severe changes in thought, behaviour or mood.
  • You notice a sudden decrease or loss of vision.
  • You experience any severe side effects persistently.
  • Your symptoms do not improve, or there is worsening of your condition.
  • You have trouble breathing or talking,
  • You have any previous mild liver or kidney condition, this medicine may need a dose adjustment.
  • You have withdrawal symptoms like agitation, nausea, tremor, sweating and confusion.

Mode of Action of Depran L Tablet

How Does It Work?

Depran L Tablet is a combination medicine that contains Clonazepam (0.25 mg) and Escitalopram (5 mg). Clonazepam( a benzodiazepine) act as GABA-A receptor agonist, GABA stands for Gamma Amino Butyric ...
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Directions for Use of Depran L Tablet

  • Take the Depran L Tablet as per the doctor.
  • You can take this medicine with or without food or as prescribed.
  • Take this medication on a regular schedule, preferably at the same time every day.
  • Do not break/crush the tablet or chew this medicine; take it as a whole.
  • Do not take this tablet with other meds, consult your doctor first.
  • Don’t stop taking this medication in between, as it may lead to withdrawal side effects.
  • Do not consume if the package has been opened.
  • Don’t exceed the dosage, even if you cannot feel its effects.

Interactions of Depran L Tablet

Interactions with other medicines

  • MAOI (monoamine oxidase inhibitors) like Selegiline, Rasagiline, Isocarboxazid, etc., is strictly contraindicated as it may cause serotonin syndrome. Serotonin syndrome can also be induced by antidepr...
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  • Interaction with metoprolol can lead to excessive bradycardia (slow heart rate).
  • Interaction with antipsychotics (pimozide, haloperidol), tricyclic antidepressants and antihistamines can prolong QT interval.
  • NSAIDs, Aspirin, and other medications which affect coagulation may interact and can increase the risk of bleeding.
  • Azole antifungals, clarithromycin or CYP2C19 inhibitors (e.g. fluconazole, fluvoxamine, omeprazole) interaction may cause increased serum levels.

Interactions with food items

  • Food doesn’t influence the effect of the Depran L Tablet. However, avoid consuming this medicine with cola drinks, chocolates and caffeine-containing food items as it can result in serotonin syndrome ...
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Storage and disposal of Depran L Tablet

Store Depran L Tablet away from sunlight. Ensure it is at room temperature in a cool and dry area. Medication should be away from children and pet animals in a closed or locked cabinet. Keep the medic...
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Dosage of Depran L Tablet


Depran L Tablet overdose can result in symptoms like irregular heartbeat, low blood pressure, slowing of heart rate, sleepiness, double vision, difficulty breathing, cardiac arrest, ECG changes (chang...
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Missed a Dose

If you’ve missed a dose of the Depran L Tablet, take it. If it's already time to take the next scheduled dose, then take the next scheduled dose. Do not double dose. Talk to your doctor if you have an...
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Content Details


Dr. Zishan Ahmad

Final year MBBS Student


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Is Depran L Tablet for all age groups?

A: Generally, Depran L Tablet is not recommended for children below ten years since the safety and efficacy of this medicine have not been established. Also, this medicine should be used with caution in elderly patients because they are more prone to hepatic and renal impairment.

Q: Can taking Depran L Tablet affect my sexual life?

A: Depran L Tablet can cause decreased sexual drive, problems getting an erection and ejaculating, difficulty achieving orgasm in women. These side effects usually pass on their own after a couple of weeks. However, if you experience these side effects persistently, then consult your doctor.

Q: Can I discontinue Depran L Tablet on my own after I feel improvement in my symptoms?

A: No, suddenly stopping the consumption of Depran L Tablet causes withdrawal symptoms. It may cause agitation, nausea, tremor, confusion, diarrhoea, vomiting, and sweating. Consult your doctor before stopping the consumption of the Depran L Tablet as doses need to be tapered slowly to avoid undesirable side effects.
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Last Updated on: 04 Mar 2022 | 04:52 PM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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