Tramadol Hydrochloride+Paracetamol / Acetaminophen

• According to CDSCO, Tramadol Hydrochloride+Paracetamol / Acetaminophen is used in the treatment of moderate to severe acute pain.

When should one not use Tramadol Hydrochloride+Paracetamol / Acetaminophen

• If you are hypersensitive or allergic to any of the medicine components.
• If you have known or suspected gastrointestinal obstruction, including paralytic ileus.
• It is contraindicated in children less than 12 years.
• It is contraindicated for postoperative management in children <18 years following tonsillectomy and/or adenoidectomy.
• If you have severe/acute bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment.
• If you have significant respiratory depression.
• If you suffer from severe active liver disease.

Common side effects of this drug are:

• Nausea
• Dizziness
• Indigestion, abdominal pain
• Constipation
• Confusion
• Sleepiness

Other General Warnings

• You must inform your doctor if you have any history of using habit-forming substances in the past.
• You must not take this medication without consulting a doctor. Using Tramadol Hydrochloride+Paracetamol / Acetaminophen for mild pain or minor injuries is not advisable.
• You must contact your doctor in case of dizziness, fainting, extreme tiredness, or difficulty in staying awake.
• Serious, life-threatening, or fatal respiratory depression has been reported in children treated with tramadol.
• Usage of this medicine exposes users to risks of addiction, abuse, and misuse.
• Take extra care and consult your doctor if you have liver or kidney problems or heart failure.

How Does It Work?

Interactions with other medicines

• Medications that affect the metabolism of tramadol must be avoided. These may increase or decrease the level of the medication. Some examples include amiodarone and quinidine.
• Co-administration of opioids with benzodiazepines or other CNS depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death.
• Co-administration with medicines that increase the level of serotonin in the body may increase the risk for serotonin syndrome. Serotonergic medicines include antidepressants like sertraline, escitalopram, fluoxetine, etc.
• Monoamine oxidase inhibitors (MAOIs) must not be coadministered with Tramadol Hydrochloride+Paracetamol / Acetaminophen or within 14 days of taking this medication. This can be life-threatening. Examples include Selegiline, Rasagiline.

Interactions with food items

• There are no specific interactions of Tramadol Hydrochloride+Paracetamol / Acetaminophen with food.

Overdose

Missed a Dose