Tamsulosin
Description
Tamsulosin is an alpha-adrenergic blocker commonly used to treat the symptoms o
f benign prostatic hyperplasia (BPH), which is an age-related enlargement of the prostate gland in men. The molecule works by relaxing the smooth muscles in the prostate and bladder neck, allowing urine to flow more easily and reducing symptoms such as frequent urination, straining, weak urine stream, and pain while urinating. Tamsulosin should be taken exactly as prescribed and not stopped suddenly without medical advice. Before starting the medicine, patients must inform their doctor about their complete medical history and all current medications to ensure safe use. Tamsulosin is not recommended for children or adolescents.
Uses
- To treat the symptoms due to enlarged prostate gland (benign prostatic hyperplasia) - urinary retention (stagnation of urine that could not be passed out)
- To reduce the risk of surgery (removal of the prostate)
Contraindications
When should one not use Tamsulosin
- Do not take if you are allergic to Tamsulosin or any of its components or other alpha-blockers (e.g. Prazosin, Doxazosin, Terazosin)
- Who have a history of falling in blood pressure while standing up or (orthostatic hypertension), indicated by symptoms such as dizziness, feeling light-headed or fainting
- Who have severe liver disease
Side effects
Common side effects of this drug are:
- Dizziness
- Headache
- Fall in blood pressure (orthostatic hypertension-symptoms such as dizziness, feeling light-headed or fainting)
- Swelling and irritation of the nose, runny nose (rhinitis)
- Constipation and diarrhea
- Itching, hives & rashes
- Weakness
- Feeling sick (nausea)
- Severe allergic reactions (rashes, blisters, and peeling of the skin, joint pains (Stevens-Johnsons syndrome) or skin swelling of face, below eyes and throat, causing breathing difficulty (angioedema))...
- Patients taking Tamsulosin are prone to a complication known as floppy iris syndrome (if they undergo cataract surgery that makes the operation difficult)
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You feel dizziness or light-headedness
- You have kidney problems
- You have swelling of the face or throat, rashes and itching
- If you are planning a cataract eye procedure
- This medicine is mistakenly given to children or adolescents under 18 years.
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Warfarin
- Diclofenac (pain killer voveran)
- Medicines that reduce stomach acid (Cimetidine)
- Other medicines which may block alpha-receptors (Erythromycin, Ketoconazole, etc.)
- Medicines causing hypotension (low blood pressure), if given along with Tamsulosin:
- Sildenafil, Tadalafil, Vardenafil
- Doxazosin, Prazosin, Alfuzosin
Interactions with food items
Dietary Restrictions
Dosage
Overdose
Missed a Dose
Content Details
Dr. Ravi Kakarla
MBBS, MBA
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What should I discuss with my healthcare expert before taking this medicine?
- You cannot take this drug if you are allergic to it or other drugs of the same group like Prazosin, Terazosin, Doxazosin, etc.
- Inform your physician:
- If you have severe kidney or liver disease
- If you have low blood pressure and heart disease
- If you are on a low salt diet
- If you are taking any water pill (Diuretic)
- If you have a personal or family history of prostate cancer
Q: Does Tamsulosin cure prostate enlargement?
Q: How long can I take Tamsulosin?
- Tamsulosin needs to be taken for long periods, usually years
- It is generally a safe medicine and is well tolerated in most patients
- However, it is advised to take this medicine as prescribed and not to self-medicate or self-adjust the dose









