Sotalol

Uses	Arrhythmias
Therapy	Anti-Arrhythmic
Side Effects	Tiredness or Weakness

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Molecule Description

Sotalol is an antiarrhythmic medicine. It corrects the irregularity of heartbeat.

Uses

Used in patients with a fast heartbeat
Used in patients with irregular heart rate

Contraindications

When should one not use Sotalol

There is a history of any allergic reaction with this medicine in the past
Patients with low blood pressure
Patients with a very slow heart rate
Patients with a history of asthma (difficulty in breathing)
Patients with kidney failure
Patients suﬀering from metabolic acidosis or diabetic ketoacidosis
Patients suﬀering from a condition causing discolouration (white or purple) of the hands and feet (Raynaud's syndrome)

Side effects

Common side effects of this drug are:

Side effects which might be seen with this medicine include headache, indigestion, dizziness, fatigue, weakness, tiredness, slow heart rate, pain in chest, diarrhea, nausea, vomiting, stomach upset, disturbance in sleep cycle, pain in arms and legs, decreased sexual ability, anxiety, depression, mood changes, tingling in feet and hands (pins and needles), fever, rash, hearing problems, problems with vision, changes in the way things taste.

Precautions and Warnings

Pregnancy

You should not take Sotalol during pregnancy unless your doctor thinks it is essential.

Breast Feeding

It is not advised to do breastfeeding during this course of medication.

Driving

It does not impair the driving ability but the patient should be careful if he/ she experiences a feeling of light-headedness or dizzy.

Alcohol

It is not advisable to consume alcohol if the patient is taking Sotalol, although a moderate amount of alcohol does not affect much.

Other General Warnings

Talk to your doctor if

Take Sotalol at the same time every day. Take medicine exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for a more extended period than the recommended schedule.

Mode of Action

How Does It Work?

This medicine uniformly prolongs the action potential duration in heart tissues. Its beta-blocking activity causes a reduction in heart rate and a limited decrease in the force of contraction of the heart. Like other beta-blocking medicines, Sotalol produces a gradual but significant reduction in blood pressure in high BP patients. With a single daily dose, you can maintain the control of blood pressure for 24 hours.

Interactions

Interactions with other medicines

Medicines for the treatment of high blood pressure, heart failure or an irregular heartbeat (e.g. Digoxin, Amiodarone, Verapamil, Disopyramide, Quinidine, Procainamide, and Bepridil)
Antidepressants like Terfenadine, Astemizole, Erythromycin, Halofantrine, Pentamidine, and Quinolone antibiotics
Floctafenine (a medicine used for the short term treatment of mild to moderate pain)
Calcium channel blockers e.g. Verapamil and Diltiazem
Diuretics (water tablet), Corticosteroids, Amphotericin IV and some laxatives as these lower potassium levels
Clonidine (sometimes used to treat headaches)
Insulin and other oral medicines for diabetes
Tubocurarin, Salbutamol (used in the treatment of asthma or emphysema)
Medicines for the treatment of allergies such as hay fever (e.g. antihistamines)

Interactions with food items

It has interactions with alcohol and multivitamins with minerals.

Dosage

Overdose

Symptoms of overdose include severe dizziness, fainting, unusually slower/ faster/ more irregular heartbeat, shortness of breath. The patient should consult the doctor as soon as possible.

Missed a Dose

If you miss taking a dose, do not worry, take it as soon as you remember unless it is nearly time for your next dose. Then continue as before. Do not take a double dose to make up for the skipped dose.

Frequently Asked Questions (FAQs)

You should not use this medicine if you are allergic to it or if you are pregnant or breastfeeding. Discuss all your medical conditions and allergies. Also, tell the lists of medications you are already taking.

Your doctor may get regular blood tests done to monitor sodium and potassium level, blood sugar level, kidney function and lung function while you are taking Sotalol medicine.

Patients should avoid drinking tea or coffee with Sotalol as caffeine can decrease the effectiveness of the drug.

The patient should avoid taking an antacid 2 hours before or after you take Sotalol because some antacids can make it harder for your body to absorb it.

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