Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol
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Molecule Summary
| Uses | Diabetic neuropathy |
| Therapy | Multivitamin |
| Side Effects | Headache, nausea, vomiting, stomach pain, diarrhea |
Medicines
available
19k pincodes
Molecule Description
Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol is a multivitamin supplement. It is used in patients with a condition called diabetic neuropathy. Diabetes neuropathy is a condition where certain nerves are damaged due to high blood sugar. It is characterised by an abnormal sensation of pain like needles and pins. Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol contains a combination of alpha-lipoic acid, folic acid, methylcobalamin, pyridoxine and vitamin D3 as active substances. Take this medicine in the exact dose and duration as prescribed by your doctor.
Uses
Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol is used for the treatment of diabetic neuropathy (a type of nerve damage that can occur with diabetes).
Contraindications
When should one not use Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol
- If you are allergic to this medicine or any other ingredients of Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol.
- If you have too much calcium in the blood.
- If you have malabsorption syndrome.
- If you have hypervitaminosis D (High levels of vitamin D in your body).
Side effects
Common side effects of this drug are:
- Headache
- Nausea
- Vomiting
- Stomach pain
- Diarrhoea
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You are pregnant, planning to have a baby or are breastfeeding. Do not take this medicine without consulting your doctor.
- If you have any existing medical conditions like diabetes, hypertension, kidney, liver or prostate problems or any other diseases, be sure to consult your doctor before starting Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol.
- You have a condition called malabsorption syndrome or megaloblastic anaemia.
- You have too much calcium in the blood.
- You are suffering from folate deficiency, and this medicine should be used with caution.
- You are on other medications, supplements or following any complementary or integrative health approaches.
- You should not take Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol if you are allergic to any of the components of this medicine.
- You are going to undergo any surgery or operation.
- You should avoid consuming alcohol in an excessive amount.
- You should avoid driving if you do not feel well or are unable to be alert.
- Your symptoms persist or worsen.
- This medicine should be taken in doses and duration prescribed by the doctor.
Mode of Action
How Does It Work?
- Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol works by the combined action of its five different constituents - alpha-lipoic acid, folic acid, methylcobalamin, pyridoxine, and vitamin D3.
- Alpha-lipoic acid is an antioxidant that helps in reducing the hyperglycemia-induced cell death of nerves. It can also reduce pain, abnormal sensation and numbness associated with diabetic neuropathy.
- Methylcobalamin is a form of vitamin B12 which helps in the formation of nerve cells and regeneration of damaged nerves in the brain.
- Vitamin D3 plays an important role in neuronal function, improves the synthesis of neuronal cells and can prevent damage to neurons.
- Folic acid is involved in certain reactions, such as methylation and synthesis of neurotransmitters and can improve nerve conduction in diabetic neuropathy.
- Pyridoxine, also known as vitamin B6, is a crucial component for various reactions and acts as a co-enzyme in the body.
Interactions
Interactions with other medicines
- Certain medicines can affect the way Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol works, or this medicine itself can affect the action of other medicines taken at the same time.
- You should always tell the doctor if you are taking any other medicines, herbal preparations and supplements to avoid any interaction.
- Concomitant use of Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol, along with medicines used to treat fits (phenobarbital phenytoin) and oral contraceptives, can alter its effects.
- Concomitant use along with Chloramphenicol injection may reduce the effectiveness of Chloramphenicol.
- Vitamin C, if taken along with this medicine, should be taken at least 2 hours after meals.
- Other medicines like Neomycin, Aminosalicylic acid, Isoniazid, Rifampicin (antibiotics), medicines used to treat stomach ulcers (Cimetidine, Omeprazole), Colchicine (used to treat gout), Penicillamine, Sulfasalazine (used to treat rheumatoid arthritis), Levodopa (used to treat Parkinson's disease) and potassium supplements should be used cautiously.
Dosage
Overdose
The symptoms of an overdose of Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol are headache, nausea, vomiting, constipation, diarrhoea, sweating, eating disorder, thirst, sleepiness and vertigo. If you experience any of the symptoms or in case of an overdose, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you have missed any dose of Pyridoxine Hydrochloride+Vitamin B9 / Folic Acid / Folate+Alpha Lipoic Acid+Vitamin B12 / Mecobalamin / Cynocobalamin / Methylcobalamin+Vitamin D3 / Cholecalciferol, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.
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References:
- Di Somma C, Scarano E, Barrea L, Zhukouskaya VV, Savastano S, Mele C, et al. Vitamin d and neurological diseases: an endocrine view. Int J Mol Sci [Internet]. 2022 [cited 15 June 2026]
- Mottaghi T, Khorvash F, Maracy M, Bellissimo N, Askari G. Effect of folic acid supplementation on nerve conduction velocity in diabetic polyneuropathy patients. Neurol Res.[cited 15 Jun 2026]
- Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study - PubMed [cited 15 Jun 2026]
- Effect of Combined Folic Acid, Vitamin B6, and Vitamin B12 on Cancer Risk: Results from a Randomized TrialKirke PN, Mills JL, Molloy AM, Brody LC, Scott JM. Impact of the MTHFR C677T polymorphism on risk of neural tube defects: Case-control study. BMJ. 2004 Nov 20 [cited 15 Jun 2026]
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