Pramipexole

Uses	Idiopathic Parkinson's disease
Therapy	Anti-Parkinsonian
Side Effects	Nausea, vomiting, headache

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Molecule Description

Pramipexole is used for treating the signs and symptoms of idiopathic Parkinson's disease. This medicine is not recommended for use in children and adolescents. It should be taken as directed by the doctor and in doses and duration as prescribed. Pramipexole can be taken with or without food. Before using this medicine, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.

Uses

Pramipexole is used to treat the signs and symptoms of idiopathic Parkinson's disease.

Contraindications

When should one not use Pramipexole

If you are allergic to Pramipexole or any other ingredient of this medicine.

Side effects

Common side effects of this drug are:

Headache, dizziness
Nausea, vomiting
Constipation
Tiredness
Sleepiness
Decreased appetite, weight loss
Swelling in the lower legs or hands
Abnormal uncontrolled movements
Hallucinations, confusion, insomnia, abnormal dreams

Precautions and Warnings

Pregnancy

Pramipexole should not be used during pregnancy, as there is limited information about its safety in human pregnancy. However, your doctor may give you this medicine only if it is really needed and benefit outweighs the risk. You should consult your doctor if you are pregnant or think you may be or are planning for a baby, before starting this medicine.

Breast Feeding

Pramipexole should not be used while breastfeeding as it can reduce the production of breast milk. It is also unknown if Pramipexole passes into breast milk, hence you should not breast feed, while taking this medicine. An alternative medicine is a better option and especially when nursing a new-born or premature baby.

Driving

Pramipexole may make you feel dizzy and sleepy, you should avoid driving if you do not feel well or are unable to be alert.

Alcohol

You should avoid consuming alcohol while on treatment with Pramipexole.

Other General Warnings

Talk to your doctor if

You have any problems with your kidney
You are suffering from any heart or blood vessels related diseases
You notice that you are hallucinating, develop any abnormal, uncontrolled movements, cannot keep your body upright, sleepiness, problems with your vision while on treatment with Pramipexole. You should immediately contact your doctor.
You notice any urge to behave in any abnormal way or notice any addicting behaviour like gambling, eating, etc.
You or any of your family members notice that your are suffering from any mental health problems (depression, anxiety, etc) after taking this medicine.
Pramipexole is not recommended for use in patients less than 18 years of age.

Mode of Action

How Does It Work?

Pramipexole works by stimulating the dopamine receptors in the brain, this triggers the nerve impulses that helps in controlling the body movements.

Interactions

Interactions with other medicines

Pramipexole may interact with other medicines, discuss with your doctor about all the medicines, supplements, or herbal preparations you are taking. Also, you should inform your doctor if you have a planned surgery or vaccination scheduled.
You should be cautious if you are taking any sedatives to calm you down along with this medicine.
When you start taking Pramipexole along with taking levodopa (also used to treat Parkinson's disease), your doctor will reduce the dose of levodopa.
Medicines like cimetidine (used in stomach ulcers), amantadine (used to treat Parkinson's disease), mexiletine, procainamide (used in heart problems), zidovudine (used to treat HIV infection), cisplatin (used in cancer), quinine (used in malaria) should be used with caution along with Pramipexole.

Interactions with food items

Pramipexole can be taken with or without food.

Dosage

Overdose

Symptoms of overdose include nausea, vomiting, excessive movement, hallucinations, agitation and low blood pressure. Seek urgent medical attention in case you have consumed too much of Pramipexole.

Missed a Dose

In case you've missed any dose of Pramipexole, take it as soon as you remember it. If it is almost time for the next dose, then skip the missed dose. Avoid taking a double dose to compensate for the missed dose.

Frequently Asked Questions (FAQs)

Pramipexole is used to treat the signs and symptoms of idiopathic Parkinson's disease.

No, you should not suddenly stop taking Pramipexole without first consulting your doctor. Your doctor will decrease your dose gradually over weeks before stopping it.

Pramipexole should be taken as directed by your doctor. Take it with a glass of water, with or without food. Do not cut, break or chew the medicine.

Inform the doctor about your detailed medical & surgical history Inform your doctor if you have heart, liver or kidney disease Inform your doctor if you are pregnant, breastfeeding or planning to have a baby Pramipexole may interact with other medicines, hence, inform your doctor if you are taking any other medicines including supplements or herbal products. Also inform your doctor if you are stopping any medicine.

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