Pholcodine+Promethazine

Uses	Dry cough, allergy symptoms
Therapy	Cough Cold Preparation
Side Effects	Nausea, vomiting, constipation, sleepiness, dizziness, rash, excitement, confusion, breathlessness

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Molecule Description

Pholcodine+Promethazine helps relieve dry cough. Reducing the symptoms of allergies such as stuffy nose, sneezing, runny nose, watery eyes, throat irritation, etc., are the primary uses of Pholcodine+Promethazine. The active ingredients of Pholcodine+Promethazine are promethazine and pholcodine. Promethazine is an antiallergic medicine (reduces symptoms of allergies), and pholcodine is a cough suppressant (lowers dry cough).

Uses

As per CDSCO, Pholcodine+Promethazine is indicated in treating
Dry, ticklish, unproductive cough in children over one year of age.
Symptoms of allergies such as sneezing, runny nose, congestion, watery eyes, and irritation.

Contraindications

When should one not use Pholcodine+Promethazine

If you have a known hypersensitive reaction to any of the ingredients of Pholcodine+Promethazine.
If you are using other medicines for depression or other psychological disorders.
If you have a history of asthma or other severe breathing problems.
If you currently have any severe liver or kidney impairment.
If you are at risk of severe respiratory failure and respiratory depression (slow and steady decline of breathing).

Side effects

Common side effects of this drug are:

Nausea
Dizziness
Drowsiness
Vomiting
Rash
Upset stomach
Constipation
Sweating

Precautions and Warnings

Pregnancy

Pholcodine+Promethazine is not recommended for pregnant women. It contains pholcodine that can cross the placenta and lead to withdrawal symptoms, such as irritation, vomiting, depression, etc., in the foetus. It can also cause stomach problems like constipation, indigestion, raised risk of vomiting, and aspiration pneumonia in pregnant women. Developmental defects in the baby are not well studied. Please consult a doctor before taking Pholcodine+Promethazine during pregnancy.

Breast Feeding

Pholcodine+Promethazine should not be used by nursing mothers unless indicated by the doctor. A few studies have suggested that a small amount of this medication may pass into the breastmilk. Using Pholcodine+Promethazine for the long term or in larger doses can cause excessive drowsiness and other side effects in the breastfed baby.

Driving

Do not drive after taking Pholcodine+Promethazine. It can cause side effects such as sleepiness, dizziness, and lack of focus, impairing your ability to drive or operate heavy machinery.

Alcohol

Do not consume alcohol with Pholcodine+Promethazine. It can interfere with the working of this medicine and cause increased side effects like nausea, drowsiness, dizziness, etc.

Other General Warnings

Talk to your doctor if

You have a history of any chronic condition such as heart diseases, diabetes, hyperthyroidism, etc.
You are an older adult.
You have a chronic and persistent cough along with excessive phlegm or mucous secretion.

Mode of Action

How Does It Work?

Pholcodine+Promethazine contains two active ingredients: promethazine and pholcodine.

Interactions

Interactions with other medicines

Do not use other cold and cough medicines containing similar ingredients to Pholcodine+Promethazine, as this can cause symptoms of an overdose and other side effects such as nausea, drowsiness, etc.
The use of antidepressant medications like MAOIs (monoamine oxidase inhibitors), sertraline, and amitriptyline, along with Pholcodine+Promethazine, can increase their side effects.
Some antipsychotic medicine (Haloperidol, Chlorpromazine, Clozapine) can interact with this medicine and the combination can cause muscle spasms or stiffness and difficulty in swallowing.
Pholcodine+Promethazine can reduce the effectiveness of specific antibiotics such as ciprofloxacin.
Use of any antipsychotic medicines (haloperidol), sleeping medication (alprazolam), opioid pain relievers (codeine and tramadol), muscle relaxants, and anti-seizure medicines along with Pholcodine+Promethazine can prolong the effects of drowsiness.

Interactions with food items

There is not much information available on the effects of Pholcodine+Promethazine on food. You can take this medicine with or without food.

Dosage

Overdose

An overdose of Pholcodine+Promethazine can cause excitation, confusion, respiratory depression such as slow or shallow breathing, tiredness, daytime sleepiness, low blood pressure, depression, and shortness of breath. If you experience these symptoms after taking Pholcodine+Promethazine, consult a doctor and seek medical treatment immediately.

Missed a Dose

If you have missed a single dose of Pholcodine+Promethazine, take it as soon as you remember. If you recall missing a dose when it's almost the time to take the next dose of this medicine, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Frequently Asked Questions (FAQs)

There is not enough information to indicate that Pholcodine+Promethazine affects fertility. Consult your doctor if you are planning for a pregnancy.

It isn't recommended to stop taking Pholcodine+Promethazine before consulting a doctor. Suddenly stopping this medicine may cause withdrawal symptoms such as irritation, sweating, vomiting, etc. Your cough may also return.

It is not recommended to take Pholcodine+Promethazine for a longer duration than recommended by the doctor. Using it for longer than necessary will not provide any additional benefits and may result in unwanted side effects.

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