Perindopril

Molecule Description

Perindopril is an Angiotensin Converting Enzyme inhibitors (ACE inhibitors). It

is used for controlling high blood pressure. By lowering the blood pressure, it helps to reduce the risk of stroke and heart attack.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Perindopril

High blood pressure (hypertension)
Congestive Heart failure (a condition when the heart is unable to pump enough blood to meet the body's needs)
Prevents heart attack (a situation where the blood supply to the heart is reduced or blocked) and stroke
Preserves kidney function and retina in persons with diabetes
Reduce proteinuria in diabetic and non-diabetic renal disease
Scleroderma crisis

Contraindications of Perindopril

When should one not use Perindopril

Do not take it if you are allergic to Perindopril
Do not take this medicine in pregnancy (third trimester)
Do not take if severe skin rashes with previous ACE inhibitor treatment
Do not take if you have diabetes or impaired kidney function
Do not take if you are treated with a blood pressure lowering medicine containing Aliskiren

Side effects of Perindopril

Common side effects of this drug are:

Dry cough
Swelling of the face, tongue or throat (angioedema)
Taste disturbances
Low blood pressure (hypotension)
Increases Serum Potassium in the blood
Raised liver enzymes
Headache and dizziness
Breathing difficulty, wheezing
Kidney impairment

Precautions and Warnings of Perindopril

Pregnancy

Can I take Perindopril during pregnancy?

Perindopril is not recommended in early pregnancy and should not be taken in women more than three months pregnant, as it may cause serious harm to the unborn baby (fetus).

Breast Feeding

Can I take Perindopril while breastfeeding?

Perindopril is not recommended for breastfeeding mothers. However, no significant information is available.

Driving

Can I drive if I have consumed Perindopril?

This medicine may cause dizziness or fatigue due to low blood pressure in some persons. This may affect your driving ability. Do not drive unless you are feeling well.

Alcohol

Can I consume alcohol with Perindopril?

You should avoid or should take a limited amount of alcoholic beverages during this medication, however no significant information available.

Other General Warnings

Talk to your doctor if

You have kidney disease
Perindopril should be used with precaution in persons with kidney disease. Dose adjustment is needed in such patients.
If you have liver disease, inform your doctor if you develop any signs and symptoms of jaundice or have raised liver enzymes while taking this medicine. In such cases, dose adjustment of this medicine...
Read more

Mode of Action of Perindopril

How Does It Work?

Perindopril inhibits Angiotensin Converting Enzyme (ACE). So, it decreases the activity of the Renin Angiotensin Aldosterone System (RAAS) and prevent the conversion of Angiotensin I to Angiotensin II...

Interactions of Perindopril

Interactions with other medicines

Analgesics such as Ibuprofen, Indomethacin can risk kidney problem
Water pills (Diuretics) can lower down the blood pressure
Mood stabilizer (Lithium)
Immunosuppressant medicines such as Cyclosporine
Potassium supplements or medications that raise Serum Potassium such as Spironolactone, Amiloride

Interactions with food items

You should avoid potassium supplements as they interact with Perindopril causing an increased risk of side effects. Avoid alcohol along with this medicine. Avoid excess salt, packed food, pickles, etc...

Dietary Restrictions of Perindopril

No information is available on dietary restrictions while you are taking Perindopril, consult your doctor or pharmacist for further details.

Dosage of Perindopril

Overdose

Overdose of this medicine may cause sudden kidney failure, increased heart rate (tachycardia), low blood pressure (hypotension), dizziness, anxiety, and cough, increased levels of potassium in the blo...

Missed a Dose

If you missed a dose, take the next dose as soon as you remember. Do not take a double dose if you have missed the dose.

Content Details

WRITTEN BY

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What are the precautions to take before starting this treatment?

A: While taking Perindopril, particularly during the first month of its use, preferably, it should be taken at bed time as it causes dizziness. Women should inform their doctor if they are pregnant, planning a pregnancy or are nursing mothers. You should give a history of liver or kidney disease, if any.

Q: At what time should I take medicine?

A: At the start, you should try to take it during bedtime because it may cause dizziness for the first few days.

Q: Can you take potassium supplements along with this medicine?

A: This medicine may increase the level of potassium in blood. So you should avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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