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Paclitaxel Nanoparticle

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Molecule Summary

Uses
Anti-cancer
Therapy
Anti-Neoplastic
Side Effects
Nausea, vomiting, diarrhoea, constipation
3 Step Quality
Assurance
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NPPA
Regulated

Molecule Description

Paclitaxel Nanoparticle is an anti-cancer medication containing paclitaxel as its main component. It is used in the treatment of ovarian cancer, lung cancer (non-small cell lung cancer) and breast cancer and may be given alone or in combination with other medicines. This medicine will be given to you in a hospital or clinic by a doctor or nurse. You should avoid self-injecting. Other medications can interact with this medicine, so disclose all current medications to your doctor. Before taking this medicine, inform your doctor if you have heart, liver, or kidney issues or are on infection treatment. It is not recommended during pregnancy or breastfeeding, and effective contraception is essential for both males and females during treatment to prevent pregnancy.

Uses

For the treatment of ovarian cancer, lung cancer (non-small cell lung cancer), and breast cancer.

Contraindications

When should one not use Paclitaxel Nanoparticle

  • If you are allergic to paclitaxel or any other ingredients of Paclitaxel Nanoparticle
  • If you have a low white blood cell (WBC) count, ask the doctor if you are unsure.
  • If you are a breastfeeding woman.

Side effects

Common side effects of this drug are:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Fatigue
  • Loss of appetite
  • Weakness
  • Headache
  • Dizziness
  • Chills
  • Fever
  • Cough
  • Pain in joints & muscles
  • Skin rash
  • Hair loss
  • Sleep problems
  • Weight loss
  • Low blood platelets
  • Anaemia
  • Low WBCs

Precautions and Warnings

Pregnancy

Pregnancy

Paclitaxel Nanoparticle should not be used during pregnancy & in women not using effective contraception, unless your doctor considers it essential after assessing the benefits over risks. Use effective contraception during treatment & for about 6 months after stopping the treatment. Men should also use effective contraception during treatment, as advised by your doctor.

Breast Feeding

Breast Feeding

Breastfeeding must be discontinued while on treatment with Paclitaxel Nanoparticle.

Driving

Driving

This medicine may make you feel dizzy; caution is needed while driving or operating machines.

Alcohol

Alcohol

Avoid consuming alcohol while on treatment with this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You had or still have problems with your heart, liver or kidneys
  • You notice any abnormal bruising or bleeding or develop any signs of infection while on treatment
  • You experience muscle weakness, numbness, pricking sensation, tingling, difficulty in breathing, dry cough
  • This medicine is not recommended for use in patients below 18 years of age

Mode of Action

How Does It Work?

Paclitaxel, a chemotherapy medication, works by interfering with microtubules, which are essential structures within cells. Microtubules help cells divide and function properly. Paclitaxel stabilizes microtubules, preventing them from breaking down as they normally should. This disruption in the cell division process can lead to cell death, particularly in cancer cells.

Interactions

Interactions with other medicines

  • Tell your doctor about all the medicines, supplements, or herbs you are taking to avoid any possible interaction. Also, you should inform your doctor if you have a planned surgery or vaccination schedule.
  • Especially if you are taking medicine to treat infections, psychiatric illnesses, fits, stomach ulcers, blood cholesterol levels, HIV infection or are taking blood thinning medications.

Dosage

Overdose

This medicine will be given to you by a doctor or nurse. Therefore, it is less likely that you may get an overdose on this medicine. If you experience any symptoms right after receiving this medicine, seek medical help.

Missed a Dose

The doctor or nurse usually gives this medicine in the hospital or clinic. Therefore, the chances of missing a dose are less. However, if you feel that a dose has been missed, please inform your doctor and nurse.

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