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Noradrenaline

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Molecule Summary

Uses
Hypotension, restoration of blood pressure
Therapy
Anti-Hypotensive
Side Effects
Headache, arrhythmias, anxiety, bradycardia, respiratory difficulty, ischemic (heart) injury
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Molecule Description

Noradrenaline, also known as norepinephrine, is a catecholamine used to restore blood pressure in adult patients with the acute hypotensive state.

Uses

  • Acute hypotension

Contraindications

When should one not use Noradrenaline

  • Allergy to noradrenaline

Side effects

Common side effects of this drug are:

  • Bradycardia (slow heart rate)
  • Cardiac arrhythmias (irregular heartbeat)
  • Anxiety
  • Headache
  • Respiratory difficulty

Precautions and Warnings

Pregnancy

Pregnancy

Noradrenaline may hamper blood supply to the placenta. It can also cause contractions of the uterus and lead to lack of oxygen and blood flow to the fetus in late pregnancy. Therefore, the risk and benefits should be assessed before administering Noradrenaline.

Driving

Driving

Noradrenaline is generally given in patients who are hospitalised.

Alcohol

Alcohol

No data is available for alcohol and Noradrenaline. Usually, it is given in a hospitalised patient, where alcohol consumption is completely banned.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have allergies

Mode of Action

How Does It Work?

Noradrenaline constricts the blood vessels by acting on alpha-adrenergic receptors and increases blood pressure. It also works as an inotropic stimulator of the heart.

Dosage

Overdose

Overdose may result in severe hypertension, slow heart rate (reflex bradycardia), increase in peripheral resistance and decreased cardiac output. In addition, headache, pallor, intense sweating and vomiting can be seen in overdosing. Immediate medical attention is needed for the same.

Missed a Dose

A missed dose is unlikely as it will be administered by a doctor in a hospitalised patient who is continuously being monitored.

Frequently Asked Questions (FAQs)

Noradrenaline is given by a healthcare professional in a hospital, with close monitoring, to treat acute low blood pressure. Your doctor will decide whether it is suitable for you.

When given along with furosemide, Noradrenaline may cause a drop in serum potassium levels. Tell your doctor if you are on furosemide.

Noradrenaline should be used cautiously in diabetic patients with monitoring and only when advised by a doctor.

You should give a brief medical history to your doctor, about any underlying diseases such as hypertension, hyperthyroidism, or any cardiovascular disorder and about all medicines or supplements you are currently taking.

Noradrenaline and Metformin can cause an increase in the serum concentration of norepinephrine in the blood, which can cause adverse effects. Tell your doctor if you are on Metformin for diabetes.

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