Isosorbide Dinitrate

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Molecule Description

Isosorbide Dinitrate is an ‘organic nitrate’ medicine used to treat heart disease.

Uses

Prevention and treatment of angina (chest pain), which is caused by heart disease. It is used alone or with other medicines.

Contraindications

When should one not use Isosorbide Dinitrate

Do not take this medicine if:
You are allergic to the medicine
Your haemoglobin count is low
You had a heart attack
You had a bleeding in the brain
You had a head injury
You had a low blood pressure
You have low blood volume
You are taking medicine such as Sildenafil or Riociguat

Side effects

Common side effects of this drug are:

Swelling of face or throat
Giddiness
Headache at the start of treatment
Weakness
Dizziness
Tired feeling
Rapid heartbeat

Precautions and Warnings

Pregnancy

No data available for effects of this medicine in an unborn baby when taken during pregnancy, consult your doctor before taking this medicine.

Breast Feeding

No data available whether this medicine passes into breast milk or not, consult your doctor before taking this medicine in breastfeeding.

Driving

This medicine can cause dizziness, tiredness and headache; avoid driving in such a situation.

Alcohol

Drinking alcohol with this medicine can cause dizziness and fainting; avoid drinking if you are taking this medicine.

Other General Warnings

Talk to your doctor if

You have heart disease, liver disease, kidney disease, underactive thyroid gland (hypothyroidism) or lung disease
You are under nourished
You are taking medicines for high blood pressure, depression, anxiety, migraine or medical condition called phenylketonuria

Mode of Action

How Does It Work?

This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart.

Interactions

Interactions with other medicines

This medicine should not be taken with Phosphodiesterase inhibitors such as Sildenafil (which is used in erectile dysfunction) and Riociguat (which is used in pulmonary hypertension).

Interactions with food items

No information is available on interactions of Isosorbide Dinitrate when taken with food, consult your doctor or pharmacist for further details.

Dietary Restrictions

No information is available on dietary restrictions while you are taking this medicine, consult your doctor or pharmacist for details.

Dosage

Overdose

Overdose symptoms may include severe headache, fever, confusion, dizziness or an episode of collapse. Consult with your doctor as soon as possible.

Missed a Dose

Take medicine as soon as you remember the missed dose. If your next dose is less than two hours away, skip the missed dose and use the medicine at your regular dosage schedule.

Frequently Asked Questions (FAQs)

Talk to your doctor if:You are malnourished (underfed)You have liver or kidney diseaseYou suffer from shallow body temperatureYou suffer from feeble circulationYou have been diagnosed with any of the heart conditionsYou have an abnormally low level of oxygen in the blood and impaired gas exchange due to lung disease or ischaemic heart disease

There should be a minimum gap of 6 - 8 hours between two doses of this medicine.

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