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Isopropamide+Trifluoperazine

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Molecule Summary

Uses
Irritable bowel syndrome, peptic ulcers, stress-induced acidity, medicine-induced diarrhoea.
Therapy
Drugs For Irritable Bowel Syndrome
Side Effects
Nausea, dry mouth, difficulty swallowing, weight gain, excessive thirst, blurry vision.
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Molecule Description

Isopropamide+Trifluoperazine combines two active ingredients, namely Isopropamide and Trifluoperazine. It helps relax the gastrointestinal tract muscles and bring about a calming effect on the patient's overall mood.

Uses

  • Treatment of irritable bowel syndrome.
  • Treatment of Peptic ulcers.
  • Treatment of Nervous hyperacidity (dyspepsia).
  • Management of other conditions of the stomach and intestines causing hyperacidity like irritable colon, gastritis, functional diarrhoea, or duodenitis.
  • Treatment of genitourinary spasms.

Contraindications

When should one not use Isopropamide+Trifluoperazine

If you have high blood pressure.

Side effects

Common side effects of this drug are:

  • Nausea
  • Dry mouth
  • Excessive thirst
  • Weight gain
  • Blurred vision
  • Constipation
  • Urinary retention
  • Low blood pressure

Precautions and Warnings

Pregnancy

Pregnancy

No, Isopropamide+Trifluoperazine is not prescribed during pregnancy as limited studies have shown harmful effects on the foetus. Please consult your physician if you are pregnant or planning a pregnancy while on Isopropamide+Trifluoperazine medication.

Breast Feeding

Breast Feeding

No, Isopropamide+Trifluoperazine is not advised during breastfeeding as it is known to pass through breast milk to the baby and can cause side effects like constipation, urinary retention and blurred vision.

Driving

Driving

No, you are not advised to drive or handle other heavy machinery as there is a chance you may experience side-effects of Isopropamide+Trifluoperazine like blurry vision, nausea and uncoordinated thoughts.

Alcohol

Alcohol

Alcohol is prohibited while on therapy with Isopropamide+Trifluoperazine as it carries a risk of increasing the severity of side effects like blurry vision, sleepiness and uncontrolled thinking.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have persistent side-effects, which worsen over time.
  • You want to stop taking Isopropamide+Trifluoperazine.
  • You feel there is no improvement.
  • You develop an allergy to Isopropamide+Trifluoperazine (rashes, hives, swelling on the hands or face).
  • You have missed a dose or doses of the medication.
  • You experience any other medical issues that arise after you start taking Isopropamide+Trifluoperazine.
  • Isopropamide+Trifluoperazine may worsen certain conditions like low blood pressure. Therefore, at the start of the treatment, it is advised to stand up slowly from a sitting/ lying position.

Mode of Action

How Does It Work?

Isopropamide+Trifluoperazine contains two active ingredients:

Interactions

Interactions with other medicines

  • When taken along with Anticholinergic Medications (which cause relaxation and dilation of body pathways) like Opioids, Zonisamide, Clozapine and Secretin, Isopropamide+Trifluoperazine can slow down movement immensely through the gastrointestinal tract and cause severe constipation or urinary retention.
  • If oral potassium supplements are taken along with Isopropamide+Trifluoperazine, they can cause an ulcer if the potassium remains in the stomach or intestine too long.
  • Antipsychotics like Phenothiazine can increase side effects like dry mouth, sleepiness, blurry vision and constipation when taken along with Isopropamide+Trifluoperazine.
  • Antiepileptics like Topiramate can increase your chances of getting a heat stroke when taken along with Isopropamide+Trifluoperazine. Symptoms include excessive dehydration, thirst, cold and clammy skin, rapid heart rate and breathing or urinating much less than usual.

Interactions with food items

  • Isopropamide+Trifluoperazine has no major reported cases of adverse food reactions.

Dosage

Overdose

  • Overdose of Isopropamide+Trifluoperazine can cause severe side-effects like dilated pupils, high fever, very high pulse rate, increased breathing and uncoordinated thoughts. Severe overdose can also cause depression and cardiac collapse.
  • Any overdose of Isopropamide+Trifluoperazine should be immediately reported to the emergency department or your nearest healthcare provider.

Missed a Dose

If you miss a dose of Isopropamide+Trifluoperazine, you can take the missed dose as soon as you realise that you have missed the dose. If the next scheduled dose is only a few hours away, it is advised not to take the missed dose and directly take the next scheduled dose and then continue as usual. Do not double your dose without consulting your physician.

Frequently Asked Questions (FAQs)

Isopropamide+Trifluoperazine is used along with other medications to treat stomach and intestinal problems related to hyperacidity and diarrhoea. You may notice an improvement in your condition in 3-7 days of starting the treatment.

Isopropamide+Trifluoperazine can be taken before or after meals depending on what is prescribed by your physician after evaluating your condition. It is recommended to take Isopropamide+Trifluoperazine always as prescribed.

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